BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7
96 results:

  • 1. [The association between baseline TPOAb and/or TgAb positivity and thyroid immune-related adverse events in patients with malignancies following treatment with immune checkpoint inhibitors].
    Gao Y; Ye T; Wu LG; Xu Y; Wang X; Cheng XQ; Zhang YL; Wang YY; Fan XR; Zhao HT; Liu H; Chai XF; Zhang L; Wang MZ; Li NS; Lian XL
    Zhonghua Yi Xue Za Zhi; 2024 Mar; 104(12):963-969. PubMed ID: 38514346
    [No Abstract]    [Full Text] [Related]  

  • 2. Nuclear translocation of metabolic enzyme PKM2 participates in high glucose-promoted HCC metastasis by strengthening immunosuppressive environment.
    Qian J; Huang C; Wang M; Liu Y; Zhao Y; Li M; Zhang X; Gao X; Zhang Y; Wang Y; Huang J; Li J; Zhou Q; Liu R; Wang X; Cui J; Yang Y
    Redox Biol; 2024 May; 71():103103. PubMed ID: 38471282
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Menin-mll1 Interaction Small Molecule Inhibitors: A Potential Therapeutic Strategy for Leukemia and cancers.
    Shi Q; Xu M; Kang Z; Zhang M; Luo Y
    Molecules; 2023 Mar; 28(7):. PubMed ID: 37049787
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
    Liao X; Li Z; Zheng H; Qian W; Zhang S; Chen S; Li X; Tang M; Xu Y; Yu R; Li M; Song L; Li J
    Mol Cancer Res; 2023 Jul; 21(7):648-663. PubMed ID: 36961398
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Calycosin-7-glucoside promotes mitochondria-mediated apoptosis in hepatocellular carcinoma by targeting thioredoxin 1 to regulate oxidative stress.
    Wei X; Zeng Y; Meng F; Wang T; Wang H; Yuan Y; Li D; Zhao Y
    Chem Biol Interact; 2023 Apr; 374():110411. PubMed ID: 36812960
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice.
    Qian F; Arner BE; Nettleford SK; Paulson RF; Prabhu KS
    J Vis Exp; 2023 Jan; (191):. PubMed ID: 36688561
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene.
    Jurutka PW; di Martino O; Reshi S; Mallick S; Sausedo MA; Moen GA; Lee IJ; Ivan DJ; Krall TD; Peoples SJ; Perez A; Tromba L; Le A; Khadka I; Petros R; Savage BM; Salama E; Salama J; Ziller JW; Noh Y; Lee MY; Liu W; Welch JS; Marshall PA; Wagner CE
    Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555852
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling.
    Huang WY; Liao ZB; Zhang JC; Zhang X; Zhang HW; Liang HF; Zhang ZY; Yang T; Yu J; Dong KS
    Cell Death Dis; 2022 Nov; 13(11):917. PubMed ID: 36319631
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Molecular deciphering of primary liver neuroendocrine neoplasms confirms their distinct existence with foregut-like profile.
    de Mestier L; Nicolle R; Poté N; Rebours V; Cauchy F; Hentic O; Maire F; Ronot M; Lebtahi R; Sauvanet A; Paradis V; Ruszniewski P; Couvelard A; Cros J
    J Pathol; 2022 Sep; 258(1):58-68. PubMed ID: 35681273
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Rat prostate tumors induce DNA synthesis in remote organs.
    Halin Bergström S; Lundholm M; Nordstrand A; Bergh A
    Sci Rep; 2022 May; 12(1):7908. PubMed ID: 35551231
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Global, regional and national burden of primary liver cancer by subtype.
    Rumgay H; Ferlay J; de Martel C; Georges D; Ibrahim AS; Zheng R; Wei W; Lemmens VEPP; Soerjomataram I
    Eur J Cancer; 2022 Jan; 161():108-118. PubMed ID: 34942552
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A human fetal liver-derived infant mll-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program.
    Rice S; Jackson T; Crump NT; Fordham N; Elliott N; O'Byrne S; Fanego MDML; Addy D; Crabb T; Dryden C; Inglott S; Ladon D; Wright G; Bartram J; Ancliff P; Mead AJ; Halsey C; Roberts I; Milne TA; Roy A
    Nat Commun; 2021 Nov; 12(1):6905. PubMed ID: 34824279
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Comparison of Interferon-α-based therapy and nucleos(t)ide analogs in preventing adverse outcomes in patients with chronic hepatitis B.
    Mao QG; Liang HQ; Yin YL; Tang JM; Yang JE; Wu CC; Chen Y; Zhang MY; Liu YY; Zheng XT; Zhuang LY; Chen SD
    Clin Res Hepatol Gastroenterol; 2022 Jan; 46(1):101758. PubMed ID: 34303003
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Design, synthesis and biological evaluations of diverse Michael acceptor-based phenazine hybrid molecules as TrxR1 inhibitors.
    Zhong Y; Liu J; Cheng X; Zhang H; Zhang C; Xia Z; Wu Z; Zhang L; Zheng Y; Gao Z; Jiang Z; Wang Z; Huang D; Lu Y; Jiang F
    Bioorg Chem; 2021 Apr; 109():104736. PubMed ID: 33640630
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression.
    Midorikawa Y; Yamamoto S; Tatsuno K; Renard-Guillet C; Tsuji S; Hayashi A; Ueda H; Fukuda S; Fujita T; Katoh H; Ishikawa S; Covington KR; Creighton CJ; Sugitani M; Wheeler DA; Shibata T; Nagae G; Takayama T; Aburatani H
    Cancer Res; 2020 Sep; 80(18):3810-3819. PubMed ID: 32641413
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. TXNIP induces growth arrest and enhances ABT263-induced apoptosis in mixed-lineage leukemia-rearranged acute myeloid leukemia cells.
    Noura M; Matsuo H; Koyama A; Adachi S; Masutani H
    FEBS Open Bio; 2020 Aug; 10(8):1532-1541. PubMed ID: 32511893
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Development of embryonic and adult leukemia mouse models driven by mll-ENL translocation.
    Sinha R; Porcheri C; d'Altri T; González J; Ruiz-Herguido C; Rabbitts T; Espinosa L; Bigas A
    Exp Hematol; 2020 May; 85():13-19. PubMed ID: 32437911
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer.
    González R; Rodríguez-Hernández MA; Negrete M; Ranguelova K; Rossin A; Choya-Foces C; Cruz-Ojeda P; Miranda-Vizuete A; Martínez-Ruiz A; Rius-Pérez S; Sastre J; Bárcena JA; Hueber AO; Padilla CA; Muntané J
    Redox Biol; 2020 Jul; 34():101528. PubMed ID: 32388267
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis.
    Ding W; Tan Y; Qian Y; Xue W; Wang Y; Jiang P; Xu X
    PLoS One; 2019; 14(10):e0223971. PubMed ID: 31618252
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas.
    Ding X; He M; Chan AWH; Song QX; Sze SC; Chen H; Man MKH; Man K; Chan SL; Lai PBS; Wang X; Wong N
    Gastroenterology; 2019 Dec; 157(6):1630-1645.e6. PubMed ID: 31560893
    [TBL] [Abstract] [Full Text] [Related]  


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