Terms: = Liver cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1
163 results:
1. Systemic loss of CD36 aggravates NAFLD-related HCC through mek1/2-ERK1/2 signaling pathway.
Zheng E; Chen Q; Xiao A; Luo X; Lu Q; Tian C; Liu H; Zhao J; Wei L; Yang P; Chen Y
Biochem Biophys Res Commun; 2024 May; 707():149781. PubMed ID: 38492244
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2. CircPCNXL2 promotes tumor growth and metastasis by interacting with STRAP to regulate ERK signaling in intrahepatic cholangiocarcinoma.
Liu S; Wang Y; Wang T; Shi K; Fan S; Li C; Chen R; Wang J; Jiang W; Zhang Y; Chen Y; Xu X; Yu Y; Li C; Li X
Mol Cancer; 2024 Feb; 23(1):35. PubMed ID: 38365721
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3. CENPL accelerates cell proliferation, cell cycle, apoptosis, and glycolysis via the mek1/2-ERK1/2 pathway in hepatocellular carcinoma.
He K; Xie M; Hong W; Li Y; Yin Y; Gao X; He Y; Chen Y; You C; Li J
Int J Biochem Cell Biol; 2024 Jan; 166():106481. PubMed ID: 37914022
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4. Identification and validation of microtubule depolymerizing agent, CYT997, as a potential drug candidate for hepatocellular carcinoma.
Ahmad F; Ma L; Wei W; Liu Y; Hakim I; Daugherty A; Mujahid S; Radin AA; Chua MS; So S
Liver Int; 2023 Dec; 43(12):2794-2807. PubMed ID: 37833852
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5. The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.
Entrialgo-Cadierno R; Cueto-Ureña C; Welch C; Feliu I; Macaya I; Vera L; Morales X; Michelina SV; Scaparone P; Lopez I; Darbo E; Erice O; Vallejo A; Moreno H; Goñi-Salaverri A; Lara-Astiaso D; Halberg N; Cortes-Dominguez I; Guruceaga E; Ambrogio C; Lecanda F; Vicent S
Mol Cancer; 2023 May; 22(1):86. PubMed ID: 37210549
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6. Genetic variants of SOS2, map2k1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients.
Lin Q; Qiu M; Wei X; Xiang Z; Zhou Z; Ji I; Liang X; Zhou X; Wen Q; Liu Y; Yu H
Arch Toxicol; 2023 Jun; 97(6):1599-1611. PubMed ID: 37029817
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7. Utilizing Estra-1,3,5,16-Tetraene Scaffold: Design and Synthesis of Nitric Oxide Donors as Chemotherapeutic Resistance Combating Agents in liver cancer.
Abou-Salim MA; Shaaban MA; Abd El Hameid MK; Alanazi MM; Halaweish F; Elshaier YAMM
Molecules; 2023 Mar; 28(6):. PubMed ID: 36985726
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8. 5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Wu C; Liu D; Zhang L; Wang J; Ding Y; Sun Z; Wang W
Front Med; 2023 Jun; 17(3):476-492. PubMed ID: 36973570
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9. Pharmacological inhibition of mek1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression.
Verzijl CRC; van de Peppel IP; Eilers RE; Bloks VW; Wolters JC; Koehorst M; Kloosterhuis NJ; Havinga R; Jalving M; Struik D; Jonker JW
Biomed Pharmacother; 2023 Mar; 159():114270. PubMed ID: 36680812
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10. Cobimetinib Plus Vemurafenib in Patients With Colorectal cancer With
Klute KA; Rothe M; Garrett-Mayer E; Mangat PK; Nazemzadeh R; Yost KJ; Duvivier HL; Ahn ER; Cannon TL; Alese OB; Krauss JC; Thota R; Calfa CJ; Denlinger CS; O'Lone R; Halabi S; Grantham GN; Schilsky RL
JCO Precis Oncol; 2022 Nov; 6():e2200191. PubMed ID: 36409971
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11. Insulin Downregulates the Expression of ATP-binding Cassette Transporter A-I in Human Hepatoma Cell Line HepG2 in a FOXO1 and LXR Dependent Manner.
Shavva VS; Babina AV; Nekrasova EV; Lisunov AV; Dizhe EB; Oleinikova GN; Orlov SV
Cell Biochem Biophys; 2023 Mar; 81(1):151-160. PubMed ID: 36251137
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12. Robotic pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: Analysis of surgical outcomes and long-term prognosis in a high-volume center.
Zhang XP; Xu S; Zhao ZM; Liu Q; Zhao GD; Hu MG; Tan XL; Liu R
Hepatobiliary Pancreat Dis Int; 2023 Apr; 22(2):140-146. PubMed ID: 36171169
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13. ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma.
Wang Y; Zhang Y; Mi J; Jiang C; Wang Q; Li X; Zhao M; Geng Z; Song X; Li J; Zuo L; Ge S; Zhang Z; Wen H; Wang Z; Su F
Oncogene; 2022 Jul; 41(29):3680-3693. PubMed ID: 35725908
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14. A linkage between effectual genes in progression of CRC through canonical and non-canonical TGF-β signaling pathways.
Shirin M; Madadi S; Peyravian N; Pezeshkian Z; Rejali L; Hosseini M; Moradi A; Khanabadi B; Sherkat G; Aghdaei HA; Nazemalhosseini-Mojarad E
Med Oncol; 2022 Jan; 39(4):40. PubMed ID: 35092502
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15. CircNFIB inhibits tumor growth and metastasis through suppressing mek1/ERK signaling in intrahepatic cholangiocarcinoma.
Du J; Lan T; Liao H; Feng X; Chen X; Liao W; Hou G; Xu L; Feng Q; Xie K; Liao M; Chen X; Huang J; Yuan K; Zeng Y
Mol Cancer; 2022 Jan; 21(1):18. PubMed ID: 35039066
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16. Activation of ERK and p38 Reduces AZD8055-Mediated Inhibition of Protein Synthesis in Hepatocellular Carcinoma HepG2 Cell Line.
Jee HY; Lee YG; Lee S; Elvira R; Seo HE; Lee JY; Han J; Lee K
Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34769253
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17. Connecting copper and cancer: from transition metal signalling to metalloplasia.
Ge EJ; Bush AI; Casini A; Cobine PA; Cross JR; DeNicola GM; Dou QP; Franz KJ; Gohil VM; Gupta S; Kaler SG; Lutsenko S; Mittal V; Petris MJ; Polishchuk R; Ralle M; Schilsky ML; Tonks NK; Vahdat LT; Van Aelst L; Xi D; Yuan P; Brady DC; Chang CJ
Nat Rev Cancer; 2022 Feb; 22(2):102-113. PubMed ID: 34764459
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18. Clinical study of map2k1-mutated Langerhans cell histiocytosis in children.
Yang Y; Wang C; Wang D; Cui L; Li N; Lian H; Ma H; Zhao Y; Zhang L; Liu W; Wang Y; Wu W; Zhang R; Li Z; Wang T
J Cancer Res Clin Oncol; 2022 Sep; 148(9):2517-2527. PubMed ID: 34595543
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19. Computational Analysis of Cholangiocarcinoma Phosphoproteomes Identifies Patient-Specific Drug Targets.
Khorsandi SE; Dokal AD; Rajeeve V; Britton DJ; Illingworth MS; Heaton N; Cutillas PR
Cancer Res; 2021 Nov; 81(22):5765-5776. PubMed ID: 34551960
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20. Integrative pan-cancer analysis of mek1 aberrations and the potential clinical implications.
Zhou Z; Peng B; Li J; Gao K; Cai Y; Xu Z; Yan Y
Sci Rep; 2021 Sep; 11(1):18366. PubMed ID: 34526571
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