Terms: = Liver cancer AND MAP3K1, ENSG00000095015, 4214, Q13233, MEKK1, MEKK, MAPKKK1
22 results:
1. Whole exome sequencing identifies map3k1, MSH2, and MLH1 as potential cancer-predisposing genes in familial early-onset colorectal cancer.
Fatemi N; Tu SJ; Chung CC; Moghadam PK; Mojarad EN; Sadeghi A; Totonchi M; Aghdaei HA; Chang JG
Kaohsiung J Med Sci; 2023 Sep; 39(9):896-903. PubMed ID: 37314251
[TBL] [Abstract] [Full Text] [Related]
2. Asperulosidic Acid Restrains Hepatocellular Carcinoma Development and Enhances Chemosensitivity Through Inactivating the mekk1/NF-κB Pathway.
Li L; Qiu H
Appl Biochem Biotechnol; 2024 Jan; 196(1):1-17. PubMed ID: 37097403
[TBL] [Abstract] [Full Text] [Related]
3. Molecular profile and its clinical impact of IDH1 mutated versus IDH1 wild type intrahepatic cholangiocarcinoma.
Rimini M; Fabregat-Franco C; Burgio V; Lonardi S; Niger M; Scartozzi M; Rapposelli IG; Aprile G; Ratti F; Pedica F; Verdaguer H; Rizzato M; Nichetti F; Lai E; Cappetta A; Macarulla T; Fassan M; De Braud F; Pretta A; Simionato F; De Cobelli F; Aldrighetti L; Fornaro L; Cascinu S; Casadei-Gardini A
Sci Rep; 2022 Nov; 12(1):18775. PubMed ID: 36335135
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4. HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Yuan J; Lv T; Yang J; Wu Z; Yan L; Yang J; Shi Y; Jiang L
Cell Mol Gastroenterol Hepatol; 2023; 15(2):307-325. PubMed ID: 36244648
[TBL] [Abstract] [Full Text] [Related]
5. Preoperative serum ctDNA predicts early hepatocellular carcinoma recurrence and response to systemic therapies.
Fu Y; Yang Z; Hu Z; Yang Z; Pan Y; Chen J; Wang J; Hu D; Zhou Z; Xu L; Chen M; Zhang Y
Hepatol Int; 2022 Aug; 16(4):868-878. PubMed ID: 35674872
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6. Small-molecule IKKβ activation modulator (IKAM) targets map3k1 and inhibits pancreatic tumor growth.
Napoleon JV; Sagar S; Kubica SP; Boghean L; Kour S; King HM; Sonawane YA; Crawford AJ; Gautam N; Kizhake S; Bialk PA; Kmiec E; Mallareddy JR; Patil PP; Rana S; Singh S; Prahlad J; Grandgenett PM; Borgstahl GEO; Ghosal G; Alnouti Y; Hollingsworth MA; Radhakrishnan P; Natarajan A
Proc Natl Acad Sci U S A; 2022 May; 119(18):e2115071119. PubMed ID: 35476515
[TBL] [Abstract] [Full Text] [Related]
7. Sarcomatoid hepatocellular carcinoma: From clinical features to cancer genome.
Zhang C; Feng S; Tu Z; Sun J; Rui T; Zhang X; Huang H; Ling Q; Zheng S
Cancer Med; 2021 Sep; 10(18):6227-6238. PubMed ID: 34331411
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8. Effect of RFA and TACE combined with postoperative cytokine-induced killer cell immunotherapy in primary hepatocellular carcinoma.
Ji Q; Fu Y; Zhu X; Wang L; Ling C
J BUON; 2021; 26(1):235-242. PubMed ID: 33721457
[TBL] [Abstract] [Full Text] [Related]
9. Long noncoding RNA FOXD2-AS1 aggravates hepatocellular carcinoma tumorigenesis by regulating the miR-206/map3k1 axis.
Hu W; Feng H; Xu X; Huang X; Huang X; Chen W; Hao L; Xia W
Cancer Med; 2020 Aug; 9(15):5620-5631. PubMed ID: 32558350
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10. Establishment of a hepatocellular carcinoma patient-derived xenograft platform and its application in biomarker identification.
Hu B; Li H; Guo W; Sun YF; Zhang X; Tang WG; Yang LX; Xu Y; Tang XY; Ding GH; Qiu SJ; Zhou J; Li YX; Fan J; Yang XR
Int J Cancer; 2020 Mar; 146(6):1606-1617. PubMed ID: 31310010
[TBL] [Abstract] [Full Text] [Related]
11. Systematic Analysis of Quantitative Logic Model Ensembles Predicts Drug Combination Effects on Cell Signaling Networks.
Morris MK; Clarke DC; Osimiri LC; Lauffenburger DA
CPT Pharmacometrics Syst Pharmacol; 2016 Oct; 5(10):544-553. PubMed ID: 27567007
[TBL] [Abstract] [Full Text] [Related]
12. Association between diabetes mellitus and cirrhosis mortality: the Singapore Chinese Health Study.
Goh GB; Pan A; Chow WC; Yuan JM; Koh WP
Liver Int; 2017 Feb; 37(2):251-258. PubMed ID: 27566448
[TBL] [Abstract] [Full Text] [Related]
13. T-Cell-Specific Deletion of map3k1 Reveals the Critical Role for mekk1 and Jnks in Cdkn1b-Dependent Proliferative Expansion.
Suddason T; Anwar S; Charlaftis N; Gallagher E
Cell Rep; 2016 Jan; 14(3):449-457. PubMed ID: 26774476
[TBL] [Abstract] [Full Text] [Related]
14. Receptor for activated C kinase 1 promotes hepatocellular carcinoma growth by enhancing mitogen-activated protein kinase kinase 7 activity.
Guo Y; Wang W; Wang J; Feng J; Wang Q; Jin J; Lv M; Li X; Li Y; Ma Y; Shen B; Zhang J
Hepatology; 2013 Jan; 57(1):140-51. PubMed ID: 22903704
[TBL] [Abstract] [Full Text] [Related]
15. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
Bai Y; Luo Y; Liu S; Zhang L; Shen K; Dong Y; Walls CD; Quilliam LA; Wells CD; Cao Y; Zhang ZY
J Biol Chem; 2011 Dec; 286(49):42316-42324. PubMed ID: 22009749
[TBL] [Abstract] [Full Text] [Related]
16. Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathological development of hepatocellular carcinoma.
Chien MH; Yeh KT; Li YC; Hsieh YH; Lin CH; Weng MS; Kuo WH; Yang SF
J Surg Oncol; 2011 Sep; 104(3):299-304. PubMed ID: 21462191
[TBL] [Abstract] [Full Text] [Related]
17. Protein O-N-acetylglucosaminylation modulates promoter activities of cyclic AMP response element and activator protein 1 and enhances E-selectin expression on HuH-7 human hepatoma cells.
Azuma Y; Miura K; Higai K; Matsumoto K
Biol Pharm Bull; 2007 Dec; 30(12):2284-9. PubMed ID: 18057713
[TBL] [Abstract] [Full Text] [Related]
18. Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells.
Chiao PJ; Na R; Niu J; Sclabas GM; Dong Q; Curley SA
Cancer; 2002 Oct; 95(8):1696-705. PubMed ID: 12365017
[TBL] [Abstract] [Full Text] [Related]
19. mekk1 induces c-Jun complexes that act as negative regulators for cell survival and proliferation of HCC cells.
Komoda F; Shino Y; Hirano T; Okutomi Y; Okamoto H; Hayashi Y; Suyama T; Ebara M; Saisho H; Shirasawa H
Int J Oncol; 2002 Sep; 21(3):553-9. PubMed ID: 12168099
[TBL] [Abstract] [Full Text] [Related]
20. Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components.
Schuringa JJ; Jonk LJ; Dokter WH; Vellenga E; Kruijer W
Biochem J; 2000 Apr; 347 Pt 1(Pt 1):89-96. PubMed ID: 10727406
[TBL] [Abstract] [Full Text] [Related]
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