BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND PIM1, PIM, 5292, ENSG00000137193, P11309
58 results:

  • 1. pim Kinase Inhibition Attenuates the Malignant Progression of Metastatic Hepatoblastoma.
    Julson JR; Quinn CH; Butey S; Erwin MH; Marayati R; Nazam N; Stewart JE; Beierle EA
    Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203596
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Combined Hepatocellular-Cholangiocarcinoma With Ductal Plate Malformation Pattern: A Case Report With Molecular Analysis.
    Moon WS; Song JS; Yu HC; Kim KM; Ahn AR
    Int J Surg Pathol; 2024 Feb; 32(1):160-164. PubMed ID: 37128663
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Exosomal miR-200b-3p induce macrophage polarization by regulating transcriptional repressor ZEB1 in hepatocellular carcinoma.
    Xu Y; Luan G; Liu F; Zhang Y; Li Z; Liu Z; Yang T
    Hepatol Int; 2023 Aug; 17(4):889-903. PubMed ID: 36930410
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Discovery of new pyridine-quinoline hybrids as competitive and non-competitive pim-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities.
    El-Miligy MMM; Abdelaziz ME; Fahmy SM; Ibrahim TM; Abu-Serie MM; Mahran MA; Hazzaa AA
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2152810. PubMed ID: 36629075
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Collaborative multi-feature extraction and scale-aware semantic information mining for medical image segmentation.
    Zhang R; He Z; Zhu J; Yuan X; Huang G; Pun CM; Peng J; Lin J; Zhou J
    Phys Med Biol; 2022 Oct; 67(20):. PubMed ID: 36170875
    [No Abstract]    [Full Text] [Related]  

  • 6. Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and pim kinase inhibition.
    Aboukhatwa SM; Ibrahim AO; Aoyama H; Al-Behery AS; Shaldam MA; El-Ashmawy G; Tawfik HO
    Bioorg Chem; 2022 Dec; 129():106126. PubMed ID: 36108589
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Ventilagolin Suppresses Migration, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells by Downregulating pim-1.
    Liu Y; Cheng DH; Lai KD; Su H; Lu GS; Wang L; Lv JH
    Drug Des Devel Ther; 2021; 15():4885-4899. PubMed ID: 34880599
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. LncRNA RGMB-AS1 facilitates pancreatic cancer cell proliferation and migration but inhibits cell apoptosis via miR-574-3p/pim3 axis.
    Song W; Shi C
    Am J Physiol Gastrointest Liver Physiol; 2021 Nov; 321(5):G477-G488. PubMed ID: 34468207
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. CRISPR/Cas9-mediated knockout of pim3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells.
    Marayati R; Stafman LL; Williams AP; Bownes LV; Quinn CH; Markert HR; Easlick JL; Stewart JE; Crossman DK; Mroczek-Musulman E; Beierle EA
    Cancer Gene Ther; 2022 May; 29(5):558-572. PubMed ID: 33864024
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches.
    Boraei ATA; Eltamany EH; Ali IAI; Gebriel SM; Nafie MS
    Bioorg Chem; 2021 Jun; 111():104877. PubMed ID: 33839579
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Therapeutic Efficacy of Combined JAK1/2, Pan-pim, and CDK4/6 Inhibition in Myeloproliferative Neoplasms.
    Rampal RK; Pinzon-Ortiz M; Somasundara AVH; Durham B; Koche R; Spitzer B; Mowla S; Krishnan A; Li B; An W; Derkach A; Devlin S; Rong X; Longmire T; Eisman SE; Cordner K; Whitfield JT; Vanasse G; Cao ZA; Levine RL
    Clin Cancer Res; 2021 Jun; 27(12):3456-3468. PubMed ID: 33782031
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. pim447 inhibits oncogenesis and potentiates cisplatin effects in hepatoblastoma.
    Wadhwani N; Markert HR; Marayati R; Bownes LV; Quinn CH; Aye JM; Stewart JE; Yoon KJ; Beierle EA
    J Pediatr Surg; 2021 Jun; 56(6):1157-1164. PubMed ID: 33762119
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. pim kinases mediate resistance to cisplatin chemotherapy in hepatoblastoma.
    Marayati R; Stafman LL; Williams AP; Bownes LV; Quinn CH; Aye JM; Stewart JE; Yoon KJ; Anderson JC; Willey CD; Beierle EA
    Sci Rep; 2021 Mar; 11(1):5984. PubMed ID: 33727604
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. pim2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway.
    Tang X; Cao T; Zhu Y; Zhang L; Chen J; Liu T; Ming X; Fang S; Yuan YF; Jiang L; Huang JD; Guan XY
    Cell Death Dis; 2020 Jul; 11(7):510. PubMed ID: 32641749
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Determining the Relative Gene Expression Level of Hypoxia Related Genes in Different cancer Cell Lines.
    Baqlouq L; Zihlif M; Hammad H; Thaib TMA
    Curr Mol Pharmacol; 2021; 14(1):52-59. PubMed ID: 32436837
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Arsenic trioxide-induced upregulation of miR-1294 suppresses tumor growth in hepatocellular carcinoma by targeting TEAD1 and pim1.
    Cai X; Yu L; Chen Z; Ye F; Ren Z; Jin P
    Cancer Biomark; 2020; 28(2):221-230. PubMed ID: 32280078
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. miR24-2 accelerates progression of liver cancer cells by activating pim1 through tri-methylation of Histone H3 on the ninth lysine.
    Yang Y; Song S; Meng Q; Wang L; Li X; Xie S; Chen Y; Jiang X; Wang C; Lu Y; Xin X; Pu H; Gui X; Li T; Xu J; Li J; Jia S; Lu D
    J Cell Mol Med; 2020 Mar; 24(5):2772-2790. PubMed ID: 32030886
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex.
    Carr RM; Romecin Duran PA; Tolosa EJ; Ma C; Oseini AM; Moser CD; Banini BA; Huang J; Asumda F; Dhanasekaran R; Graham RP; Toruner MD; Safgren SL; Almada LL; Wang S; Patnaik MM; Roberts LR; Fernandez-Zapico ME
    J Biol Chem; 2020 Feb; 295(9):2698-2712. PubMed ID: 31988246
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Midazolam inhibits proliferation and accelerates apoptosis of hepatocellular carcinoma cells by elevating microRNA-124-3p and suppressing pim-1.
    Qi Y; Yao X; Du X
    IUBMB Life; 2020 Mar; 72(3):452-464. PubMed ID: 31651086
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The presence of pim3 increases hepatoblastoma tumorigenesis and tumor initiating cell phenotype and is associated with decreased patient survival.
    Stafman LL; Waldrop MG; Williams AP; Aye JM; Stewart JE; Mroczek-Musulman E; Yoon KJ; Whelan K; Beierle EA
    J Pediatr Surg; 2019 Jun; 54(6):1206-1213. PubMed ID: 30898394
    [TBL] [Abstract] [Full Text] [Related]  


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