BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND TCF7L2, ENSG00000148737, 6934, TCF-4
55 results:

  • 1. Wnt/β-catenin signaling regulates amino acid metabolism through the suppression of CEBPA and FOXA1 in liver cancer cells.
    Nakagawa S; Yamaguchi K; Takane K; Tabata S; Ikenoue T; Furukawa Y
    Commun Biol; 2024 Apr; 7(1):510. PubMed ID: 38684876
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis.
    Sanceau J; Poupel L; Joubel C; Lagoutte I; Caruso S; Pinto S; Desbois-Mouthon C; Godard C; Hamimi A; Montmory E; Dulary C; Chantalat S; Roehrig A; Muret K; Saint-Pierre B; Deleuze JF; Mouillet-Richard S; Forné T; Grosset CF; Zucman-Rossi J; Colnot S; Gougelet A
    Mol Ther; 2024 Apr; 32(4):1125-1143. PubMed ID: 38311851
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Pathway-driven analysis of synthetic lethal interactions in cancer using perturbation screens.
    Karimpour M; Totonchi M; Behmanesh M; Montazeri H
    Life Sci Alliance; 2024 Jan; 7(1):. PubMed ID: 37863651
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Identification of odontogenic ameloblast associated as a novel target gene of the Wnt/β-catenin signaling pathway.
    Yamaguchi K; Horie C; Takane K; Ikenoue T; Nakagawa S; Isobe Y; Ota Y; Ushiku T; Tanaka M; Fujishiro J; Hoshino N; Arisue A; Nishizuka S; Aikou S; Shida D; Furukawa Y
    Cancer Sci; 2023 Mar; 114(3):948-960. PubMed ID: 36382598
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. β-catenin cancer-enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma.
    Gulati R; Johnston M; Rivas M; Cast A; Kumbaji M; Hanlon MA; Lee S; Zhou P; Lake C; Schepers E; Min KW; Yoon JH; Karns R; Reid LM; Lopez-Terrada D; Timchenko L; Parameswaran S; Weirauch MT; Ranganathan S; Bondoc A; Geller J; Tiao G; Shin S; Timchenko N
    Hepatol Commun; 2022 Oct; 6(10):2950-2963. PubMed ID: 36000549
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Ubiquitin-specific protease 28 deubiquitinates tcf7l2 to govern the action of the Wnt signaling pathway in hepatic carcinoma.
    Sun X; Cai M; Wu L; Zhen X; Chen Y; Peng J; Han S; Zhang P
    Cancer Sci; 2022 Oct; 113(10):3463-3475. PubMed ID: 35880246
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Circ_0000775 promotes the migration, invasion and EMT of hepatic carcinoma cells by recruiting IGF2BP2 to stabilize CDC27.
    Zhao C; Sun J; Dang Z; Su Q; Yang J
    Pathol Res Pract; 2022 Jul; 235():153908. PubMed ID: 35561648
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Kindlin-2-miR-1258-TCF4 feedback loop promotes hepatocellular carcinoma invasion and metastasis.
    Lin W; Lin J; Li J; Lin Y; Chen S; Wu Y; Chen L; Cheng H; Liu L; Chen X; Ye Y
    J Gastroenterol; 2022 May; 57(5):372-386. PubMed ID: 35244769
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The role of transcription factor 7-like 2 in metabolic disorders.
    Zhang Z; Xu L; Xu X
    Obes Rev; 2021 May; 22(5):e13166. PubMed ID: 33615650
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs.
    Foster DJ; Chang HM; Haswell JR; Gregory RI; Slack FJ
    Cell Cycle; 2020 Sep; 19(18):2314-2326. PubMed ID: 32816599
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism.
    Ali N; Nguyen CB; Chandrakesan P; Wolf RF; Qu D; May R; Goretsky T; Fazili J; Barrett TA; Li M; Huycke MM; Bronze MS; Houchen CW
    Sci Rep; 2020 Jun; 10(1):10578. PubMed ID: 32601309
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer.
    Dietinger V; García de Durango CR; Wiechmann S; Boos SL; Michl M; Neumann J; Hermeking H; Kuster B; Jung P
    Cell Commun Signal; 2020 Jun; 18(1):102. PubMed ID: 32586342
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The β-catenin/tcf-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis.
    Huang WJ; Tian XP; Bi SX; Zhang SR; He TS; Song LY; Yun JP; Zhou ZG; Yu RM; Li M
    Oncogene; 2020 Jun; 39(23):4538-4550. PubMed ID: 32372060
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes.
    Liu P; Liang B; Liu M; Lebbink JHG; Li S; Qian M; Lavrijsen M; Peppelenbosch MP; Chen X; Smits R
    Gastroenterology; 2020 Mar; 158(4):1029-1043.e10. PubMed ID: 31857074
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. KIFC1 is activated by tcf-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity.
    Teng K; Wei S; Zhang C; Chen J; Chen J; Xiao K; Liu J; Dai M; Guan X; Yun J; Xie D
    J Exp Clin Cancer Res; 2019 Jul; 38(1):329. PubMed ID: 31340839
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Long Noncoding RNA MALAT1 Regulates cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of tcf7l2.
    Malakar P; Stein I; Saragovi A; Winkler R; Stern-Ginossar N; Berger M; Pikarsky E; Karni R
    Cancer Res; 2019 May; 79(10):2480-2493. PubMed ID: 30914432
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. [Genes and molecular mechanisms affecting the correlation between liver cancer and diabetes mellitus].
    Yang Y; Zhang BH; Gong JP
    Zhonghua Gan Zang Bing Za Zhi; 2018 Sep; 26(9):718-720. PubMed ID: 30481877
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Canonical Wnt Signaling Remodels Lipid Metabolism in Zebrafish Hepatocytes following Ras Oncogenic Insult.
    Yao Y; Sun S; Wang J; Fei F; Dong Z; Ke AW; He R; Wang L; Zhang L; Ji MB; Li Q; Yu M; Shi GM; Fan J; Gong Z; Wang X
    Cancer Res; 2018 Oct; 78(19):5548-5560. PubMed ID: 30065049
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Hsa-let-7b inhibits cell proliferation by targeting PLK1 in HCC.
    He Z; Deng W; Jiang B; Liu S; Tang M; Liu Y; Zhang J
    Gene; 2018 Oct; 673():46-55. PubMed ID: 29913237
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The transcription factor 7 like 2‑binding protein TIP5 activates β‑catenin/transcription factor signaling in hepatocellular carcinoma.
    Li C; Wu W; Ding H; Li Q; Xie K
    Mol Med Rep; 2018 Jun; 17(6):7645-7651. PubMed ID: 29620186
    [TBL] [Abstract] [Full Text] [Related]  


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