BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND TGFBR2, AAT3, 7048, ENSG00000163513, P37173, TGFbeta-RII, RIIC, TAAD2, FAA3, TGFR-2, MFS2, HNPCC6
34 results:

  • 1. TGF-β1 induces PD-1 expression in macrophages through SMAD3/STAT3 cooperative signaling in chronic inflammation.
    Lei Z; Tang R; Wu Y; Mao C; Xue W; Shen J; Yu J; Wang X; Qi X; Wei C; Xu L; Zhu J; Li Y; Zhang X; Ye C; Chen X; Yang X; Zhou S; Su C
    JCI Insight; 2024 Mar; 9(7):. PubMed ID: 38441961
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Potential crosstalk between SPP1 + TAMs and CD8 + exhausted T cells promotes an immunosuppressive environment in gastric metastatic cancer.
    Du Y; Lin Y; Gan L; Wang S; Chen S; Li C; Hou S; Hu B; Wang B; Ye Y; Shen Z
    J Transl Med; 2024 Feb; 22(1):158. PubMed ID: 38365757
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma.
    Yang X; Lian B; Zhang N; Long J; Li Y; Xue J; Chen X; Wang Y; Wang Y; Xun Z; Piao M; Zhu C; Wang S; Sun H; Song Z; Lu L; Dong X; Wang A; Liu W; Pan J; Hou X; Guan M; Huo L; Shi J; Zhang H; Zhou J; Lu Z; Mao Y; Sang X; Wu L; Yang X; Wang K; Zhao H
    BMC Med; 2024 Jan; 22(1):42. PubMed ID: 38281914
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. ST6GALNAC4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation.
    Man D; Jiang Y; Zhang D; Wu J; Ding B; Liu H; Xu G; Lu J; Ru J; Tong R; Zheng S; Chen D; Wu J
    J Transl Med; 2023 Jun; 21(1):420. PubMed ID: 37381011
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Frequent loss of metastatic ability in subclones of Apc, Kras, tgfbr2, and Trp53 mutant intestinal tumor organoids.
    Morita A; Nakayama M; Wang D; Murakami K; Oshima M
    Cancer Sci; 2023 Apr; 114(4):1437-1450. PubMed ID: 36576236
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Down-regulation of hepatic expression of GHR/STAT5/IGF-1 signaling pathway fosters development and aggressiveness of HCV-related hepatocellular carcinoma: Crosstalk with Snail-1 and type 2 transforming growth factor-beta receptor.
    Abu El-Makarem MA; Kamel MF; Mohamed AA; Ali HA; Mohamed MR; Mohamed AEM; El-Said AM; Ameen MG; Hassnine AA; Hassan HA
    PLoS One; 2022; 17(11):e0277266. PubMed ID: 36374927
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Risk Factors for Postoperative Bleeding Following Breast cancer Surgery: A Nationwide Database Study of 477,108 Cases in Japan.
    Konishi T; Fujiogi M; Shigemi D; Matsui H; Fushimi K; Tanabe M; Seto Y; Yasunaga H
    World J Surg; 2022 Dec; 46(12):3062-3071. PubMed ID: 36155832
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Imbalance of TGF-β1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness.
    Ning J; Ye Y; Bu D; Zhao G; Song T; Liu P; Yu W; Wang H; Li H; Ren X; Ying G; Zhao Y; Yu J
    Mol Ther; 2021 Jun; 29(6):2067-2087. PubMed ID: 33601054
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Targeted sequencing of cancer-related genes in nasopharyngeal carcinoma identifies mutations in the TGF-β pathway.
    Chung AK; OuYang CN; Liu H; Chao M; Luo JD; Lee CY; Lu YJ; Chung IC; Chen LC; Wu SM; Tsang NM; Chang KP; Hsu CL; Li HP; Chang YS
    Cancer Med; 2019 Sep; 8(11):5116-5127. PubMed ID: 31328403
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.
    Wang B; Xu X; Yang Z; Zhang L; Liu Y; Ma A; Xu G; Tang M; Jing T; Wu L; Liu Y
    EBioMedicine; 2019 Mar; 41():320-332. PubMed ID: 30745168
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Long Noncoding RNA HOTTIP Promotes Mouse Hepatic Stellate Cell Activation via Downregulating miR-148a.
    Li Z; Wang J; Zeng Q; Hu C; Zhang J; Wang H; Yan J; Li H; Yu Z
    Cell Physiol Biochem; 2018; 51(6):2814-2828. PubMed ID: 30562760
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. HANR promotes hepatocellular carcinoma progression via miR-214/EZH2/TGF-β axis.
    Shi Y; Yang X; Xue X; Sun D; Cai P; Song Q; Zhang B; Qin L
    Biochem Biophys Res Commun; 2018 Nov; 506(1):189-193. PubMed ID: 30342849
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A Transforming Growth Factor-β and H19 Signaling Axis in Tumor-Initiating Hepatocytes That Regulates Hepatic Carcinogenesis.
    Zhang J; Han C; Ungerleider N; Chen W; Song K; Wang Y; Kwon H; Ma W; Wu T
    Hepatology; 2019 Apr; 69(4):1549-1563. PubMed ID: 30014520
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A mutational signature associated with alcohol consumption and prognostically significantly mutated driver genes in esophageal squamous cell carcinoma.
    Li XC; Wang MY; Yang M; Dai HJ; Zhang BF; Wang W; Chu XL; Wang X; Zheng H; Niu RF; Zhang W; Chen KX
    Ann Oncol; 2018 Apr; 29(4):938-944. PubMed ID: 29351612
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Combined Mutation of
    Sakai E; Nakayama M; Oshima H; Kouyama Y; Niida A; Fujii S; Ochiai A; Nakayama KI; Mimori K; Suzuki Y; Hong CP; Ock CY; Kim SJ; Oshima M
    Cancer Res; 2018 Mar; 78(5):1334-1346. PubMed ID: 29282223
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Unravelling the link between embryogenesis and cancer metastasis.
    Shah K; Patel S; Mirza S; Rawal RM
    Gene; 2018 Feb; 642():447-452. PubMed ID: 29162510
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. YAP-1 Promotes Tregs Differentiation in Hepatocellular Carcinoma by Enhancing tgfbr2 Transcription.
    Fan Y; Gao Y; Rao J; Wang K; Zhang F; Zhang C
    Cell Physiol Biochem; 2017; 41(3):1189-1198. PubMed ID: 28472799
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic cancer.
    Zhong Y; Macgregor-Das A; Saunders T; Whittle MC; Makohon-Moore A; Kohutek ZA; Poling J; Herbst BT; Javier BM; Cope L; Leach SD; Hingorani SR; Iacobuzio-Donahue CA
    Clin Cancer Res; 2017 Mar; 23(6):1607-1620. PubMed ID: 27637888
    [No Abstract]    [Full Text] [Related]  

  • 19. Interferon-microRNA signalling drives liver precancerous lesion formation and hepatocarcinogenesis.
    Yang Y; Lin X; Lu X; Luo G; Zeng T; Tang J; Jiang F; Li L; Cui X; Huang W; Hou G; Chen X; Ouyang Q; Tang S; Sun H; Chen L; Gonzalez FJ; Wu M; Cong W; Chen L; Wang H
    Gut; 2016 Jul; 65(7):1186-201. PubMed ID: 26860770
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.
    Ruzzenente A; Fassan M; Conci S; Simbolo M; Lawlor RT; Pedrazzani C; Capelli P; D'Onofrio M; Iacono C; Scarpa A; Guglielmi A
    Ann Surg Oncol; 2016 May; 23(5):1699-707. PubMed ID: 26717940
    [TBL] [Abstract] [Full Text] [Related]  


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