BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND XPO1, DKFZp686B1823, 7514, ENSG00000082898, O14980, CRM1 AND Treatment
13 results:

  • 1. Selinexor demonstrates anti-tumor efficacy in paired patient-derived xenograft models and hydrogel-embedded histoculture drug sensitivity test of penile cancer.
    He Y; Mei J; Hao H; Liu F; Yi Y; Hu C; Zou F; Lu X
    J Cancer Res Clin Oncol; 2023 Aug; 149(10):6931-6941. PubMed ID: 36840755
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. xpo1 intensifies sorafenib resistance by stabilizing acetylation of NPM1 and enhancing epithelial-mesenchymal transition in hepatocellular carcinoma.
    Wang Z; Pan B; Yao Y; Qiu J; Zhang X; Wu X; Tang N
    Biomed Pharmacother; 2023 Apr; 160():114402. PubMed ID: 36791564
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Selinexor decreases HIF-1α via inhibition of crm1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity.
    von Fallois M; Kosyna FK; Mandl M; Landesman Y; Dunst J; Depping R
    J Cancer Res Clin Oncol; 2021 Jul; 147(7):2025-2033. PubMed ID: 33856525
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Advanced liver disease outcomes after hepatitis C eradication by human immunodeficiency virus infection in PITER cohort.
    Quaranta MG; Ferrigno L; Monti M; Filomia R; Biliotti E; Iannone A; Migliorino G; Coco B; Morisco F; Vinci M; D'Ambrosio R; Chemello L; Massari M; Ieluzzi D; Russo FP; Blanc P; Verucchi G; Puoti M; Rumi MG; Barbaro F; Santantonio TA; Federico A; Chessa L; Gentile I; Zuin M; Parruti G; Morsica G; Kondili LA;
    Hepatol Int; 2020 May; 14(3):362-372. PubMed ID: 32279177
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. First-line treatment with FOLFOXIRI for advanced pancreatic cancer in clinical practice: Patients' outcome and analysis of prognostic factors.
    Vivaldi C; Caparello C; Musettini G; Pasquini G; Catanese S; Fornaro L; Lencioni M; Falcone A; Vasile E
    Int J Cancer; 2016 Aug; 139(4):938-45. PubMed ID: 27038273
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-crm1 interaction and changing the cellular compartmentalization of p53 protein.
    Ortega JF; de Conti A; Tryndyak V; Furtado KS; Heidor R; Horst MA; Fernandes LH; Tavares PE; Pogribna M; Shpyleva S; Beland FA; Pogribny IP; Moreno FS
    Oncotarget; 2016 Apr; 7(17):24339-47. PubMed ID: 27013579
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Oncogenic role of p21 in hepatocarcinogenesis suggests a new treatment strategy.
    Ohkoshi S; Yano M; Matsuda Y
    World J Gastroenterol; 2015 Nov; 21(42):12150-6. PubMed ID: 26576099
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. KPT-330 inhibitor of xpo1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma.
    Zheng Y; Gery S; Sun H; Shacham S; Kauffman M; Koeffler HP
    Cancer Chemother Pharmacol; 2014 Sep; 74(3):487-95. PubMed ID: 25030088
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Targeting the nuclear transport machinery by rational drug design.
    Mao L; Yang Y
    Curr Pharm Des; 2013; 19(12):2318-25. PubMed ID: 23082981
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Role of HSP90, CDC37, and crm1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.
    Pascale RM; Simile MM; Calvisi DF; Frau M; Muroni MR; Seddaiu MA; Daino L; Muntoni MD; De Miglio MR; Thorgeirsson SS; Feo F
    Hepatology; 2005 Dec; 42(6):1310-9. PubMed ID: 16317707
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Temporal and spatial control of nucleophosmin by the Ran-crm1 complex in centrosome duplication.
    Wang W; Budhu A; Forgues M; Wang XW
    Nat Cell Biol; 2005 Aug; 7(8):823-30. PubMed ID: 16041368
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif.
    Li W; Jain MR; Chen C; Yue X; Hebbar V; Zhou R; Kong AN
    J Biol Chem; 2005 Aug; 280(31):28430-8. PubMed ID: 15917227
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha.
    Buck M; Zhang L; Halasz NA; Hunter T; Chojkier M
    EMBO J; 2001 Dec; 20(23):6712-23. PubMed ID: 11726507
    [TBL] [Abstract] [Full Text] [Related]  


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