Terms: = Lung cancer AND CDK12, KIAA0904, CRKRS, 51755, ENSG00000167258, CRK7, CRKR, Q9NYV4
22 results:
1. Trans-Regulation of Alternative
Larsen TV; Maansson CT; Daugaard TF; Andresen BS; Sorensen BS; Nielsen AL
Cells; 2023 Dec; 12(24):. PubMed ID: 38132164
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2. E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma.
Liu K; Wang L; Lou Z; Guo L; Xu Y; Qi H; Fang Z; Mei L; Chen X; Zhang X; Shao J; Xiang X
Biochem Pharmacol; 2023 Dec; 218():115854. PubMed ID: 37863324
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3. cdk12 loss inhibits cell proliferation by regulating TBK1 in non-small cell lung cancer cells.
Liu X; Liu Y; Chai W; Yan M; Li H; Li J; Sun L; Cao Y; Liu Q; Sun Y; Pan H
Mol Cell Probes; 2023 Oct; 71():101923. PubMed ID: 37517598
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4. PhosphoDisco: A Toolkit for Co-regulated Phosphorylation Module Discovery in Phosphoproteomic Data.
Schraink T; Blumenberg L; Hussey G; George S; Miller B; Mathew N; González-Robles TJ; Sviderskiy V; Papagiannakopoulos T; Possemato R; Fenyö D; Ruggles KV
Mol Cell Proteomics; 2023 Aug; 22(8):100596. PubMed ID: 37394063
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5. Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort.
Leibowitz BD; Dougherty BV; Bell JSK; Kapilivsky J; Michuda J; Sedgewick AJ; Munson WA; Chandra TA; Dry JR; Beaubier N; Igartua C; Taxter T
BMC Cancer; 2022 May; 22(1):587. PubMed ID: 35643464
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6. Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer.
Necchi A; Cucchiara V; Grivas P; Bratslavsky G; Jacob J; Spiess PE; Sokol ES; Killian JK; Lin D; Ramkissoon S; Huang RSP; Madison RW; Venstrom JM; Schrock AB; Danziger N; Decker B; Gjoerup O; Graf RP; Oxnard GR; Tukachinsky H; Ross JS
Cancer; 2021 Dec; 127(24):4557-4564. PubMed ID: 34379803
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7. Poor prognosis of male triple-positive breast cancer patients: a propensity score matched SEER analysis and molecular portraits.
Wang B; Wang H; Zhao A; Zhang M; Yang J
BMC Cancer; 2021 May; 21(1):523. PubMed ID: 33964913
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8. Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium.
Lin BM; Grinde KE; Brody JA; Breeze CE; Raffield LM; Mychaleckyj JC; Thornton TA; Perry JA; Baier LJ; de Las Fuentes L; Guo X; Heavner BD; Hanson RL; Hung YJ; Qian H; Hsiung CA; Hwang SJ; Irvin MR; Jain D; Kelly TN; Kobes S; Lange L; Lash JP; Li Y; Liu X; Mi X; Musani SK; Papanicolaou GJ; Parsa A; Reiner AP; Salimi S; Sheu WH; Shuldiner AR; Taylor KD; Smith AV; Smith JA; Tin A; Vaidya D; Wallace RB; Yamamoto K; Sakaue S; Matsuda K; Kamatani Y; Momozawa Y; Yanek LR; Young BA; Zhao W; Okada Y; Abecasis G; Psaty BM; Arnett DK; Boerwinkle E; Cai J; Yii-Der Chen I; Correa A; Cupples LA; He J; Kardia SL; Kooperberg C; Mathias RA; Mitchell BD; Nickerson DA; Turner ST; Vasan RS; Rotter JI; Levy D; Kramer HJ; Köttgen A; Nhlbi Trans-Omics For Precision Medicine TOPMed Consortium ; TOPMed Kidney Working Group ; Rich SS; Lin DY; Browning SR; Franceschini N
EBioMedicine; 2021 Jan; 63():103157. PubMed ID: 33418499
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9. Mutation profile of non-small cell lung cancer revealed by next generation sequencing.
Chang YS; Tu SJ; Chen YC; Liu TY; Lee YT; Yen JC; Fang HY; Chang JG
Respir Res; 2021 Jan; 22(1):3. PubMed ID: 33407425
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10. Differences in Genomic Alterations Between Brain Metastases and Primary Tumors.
Dono A; Takayasu T; Yan Y; Bundrant BE; Arevalo O; Lopez-Garcia CA; Esquenazi Y; Ballester LY
Neurosurgery; 2021 Feb; 88(3):592-602. PubMed ID: 33369669
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11. Isoorientin induces the apoptosis and cell cycle arrest of A549 human lung cancer cells via the ROS‑regulated MAPK, STAT3 and NF‑κB signaling pathways.
Xu WT; Shen GN; Li TZ; Zhang Y; Zhang T; Xue H; Zuo WB; Li YN; Zhang DJ; Jin CH
Int J Oncol; 2020 Aug; 57(2):550-561. PubMed ID: 32626938
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12. cdk12 Promotes Breast cancer Progression and Maintains Stemness by Activating c-myc/β -catenin Signaling.
Peng F; Yang C; Kong Y; Huang X; Chen Y; Zhou Y; Xie X; Liu P
Curr Cancer Drug Targets; 2020; 20(2):156-165. PubMed ID: 31744448
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13. Enhancement of Radiosensitivity by Eurycomalactone in Human NSCLC Cells Through G₂/M Cell Cycle Arrest and Delayed DNA Double-Strand Break Repair.
Dukaew N; Konishi T; Chairatvit K; Autsavapromporn N; Soonthornchareonnon N; Wongnoppavich A
Oncol Res; 2020 Mar; 28(2):161-175. PubMed ID: 31727206
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14. Ex vivo screen identifies cdk12 as a metastatic vulnerability in osteosarcoma.
Bayles I; Krajewska M; Pontius WD; Saiakhova A; Morrow JJ; Bartels C; Lu J; Faber ZJ; Fedorov Y; Hong ES; Karnuta JM; Rubin B; Adams DJ; George RE; Scacheri PC
J Clin Invest; 2019 Oct; 129(10):4377-4392. PubMed ID: 31498151
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15. Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic lung Adenocarcinoma and Validate a Novel Somatic Mutation cdk12-G879V.
Zhang X; Nguyen KD; Rudnick PA; Roper N; Kawaler E; Maity TK; Awasthi S; Gao S; Biswas R; Venugopalan A; Cultraro CM; Fenyö D; Guha U
Mol Cell Proteomics; 2019 Apr; 18(4):622-641. PubMed ID: 30617155
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16. Anti-proliferative effect of 8α-tigloyloxyhirsutinolide-13-O-acetate (8αTGH) isolated from Vernonia cinerea on oral squamous cell carcinoma through inhibition of STAT3 and STAT2 phosphorylation.
Pouyfung P; Choonate S; Wongnoppavich A; Rongnoparut P; Chairatvit K
Phytomedicine; 2019 Jan; 52():238-246. PubMed ID: 30599904
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17. Expression of cyclin B1, D1 and K in non‑small cell lung cancer H1299 cells following treatment with sulforaphane.
Żuryń A; Krajewski A; Klimaszewska-Wiśniewska A; Grzanka A; Grzanka D
Oncol Rep; 2019 Feb; 41(2):1313-1323. PubMed ID: 30535470
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18. Structural Alterations Driving Castration-Resistant Prostate cancer Revealed by Linked-Read Genome Sequencing.
Viswanathan SR; Ha G; Hoff AM; Wala JA; Carrot-Zhang J; Whelan CW; Haradhvala NJ; Freeman SS; Reed SC; Rhoades J; Polak P; Cipicchio M; Wankowicz SA; Wong A; Kamath T; Zhang Z; Gydush GJ; Rotem D; ; Love JC; Getz G; Gabriel S; Zhang CZ; Dehm SM; Nelson PS; Van Allen EM; Choudhury AD; Adalsteinsson VA; Beroukhim R; Taplin ME; Meyerson M
Cell; 2018 Jul; 174(2):433-447.e19. PubMed ID: 29909985
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19. Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors.
Gao Y; Zhang T; Terai H; Ficarro SB; Kwiatkowski N; Hao MF; Sharma B; Christensen CL; Chipumuro E; Wong KK; Marto JA; Hammerman PS; Gray NS; George RE
Cell Chem Biol; 2018 Feb; 25(2):135-142.e5. PubMed ID: 29276047
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20. Screening of gene mutations associated with bone metastasis in nonsmall cell lung cancer.
Zhang K; Zhang M; Zhu J; Hong W
J Cancer Res Ther; 2016 Dec; 12(Supplement):C186-C190. PubMed ID: 28230015
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