Terms: = Lung cancer AND CRTC1, Q6UUV9, 23373, ENSG00000105662, KIAA0616, TORC1, MECT1, WAMTP1, FLJ14027
26 results:
1. Current diagnosis and treatment of salivary gland-type tumors of the lung.
Horio Y; Kuroda H; Masago K; Matsushita H; Sasaki E; Fujiwara Y
Jpn J Clin Oncol; 2024 Mar; 54(3):229-247. PubMed ID: 38018262
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2. Novel NCOA2/3-rearranged low-grade fibroblastic spindle cell tumors: A report of five cases.
Bakhshwin A; Armstrong SM; Duckworth LA; Stoehr R; Konishi E; Rubin BP; Fritchie KJ; Dickson BC; Agaimy A; Dermawan JK
Genes Chromosomes Cancer; 2024 Jan; 63(1):e23203. PubMed ID: 37724942
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3. Targeting NFE2L2/KEAP1 Mutations in Advanced NSCLC With the torc1/2 Inhibitor TAK-228.
Paik PK; Fan PD; Qeriqi B; Namakydoust A; Daly B; Ahn L; Kim R; Plodkowski A; Ni A; Chang J; Fanaroff R; Ladanyi M; de Stanchina E; Rudin CM
J Thorac Oncol; 2023 Apr; 18(4):516-526. PubMed ID: 36240971
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4. Thymic Mucoepidermoid Carcinoma: A Clinicopathologic and Molecular Study.
Murase T; Nakano S; Sakane T; Domen H; Chiyo M; Nagasaka S; Tanaka M; Kawahara Y; Toishi M; Tanaka T; Nakamura S; Sawabata N; Okami J; Mukaida H; Tzankov A; Szolkowska M; Porubsky S; Marx A; Roden AC; Inagaki H
Am J Surg Pathol; 2022 Aug; 46(8):1160-1169. PubMed ID: 35319525
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5. Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation.
Zhou X; Li JW; Chen Z; Ni W; Li X; Yang R; Shen H; Liu J; DeMayo FJ; Lu J; Kaye FJ; Wu L
Elife; 2021 Jun; 10():. PubMed ID: 34142658
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6. Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations.
Ogino A; Choi J; Lin M; Wilkens MK; Calles A; Xu M; Adeni AE; Chambers ES; Capelletti M; Butaney M; Gray NS; Gokhale PC; Palakurthi S; Kirschmeier P; Oxnard GR; Sholl LM; Jänne PA
Mol Oncol; 2021 Jan; 15(1):27-42. PubMed ID: 32191822
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7. Vistusertib (dual m-torc1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer.
Basu B; Krebs MG; Sundar R; Wilson RH; Spicer J; Jones R; Brada M; Talbot DC; Steele N; Ingles Garces AH; Brugger W; Harrington EA; Evans J; Hall E; Tovey H; de Oliveira FM; Carreira S; Swales K; Ruddle R; Raynaud FI; Purchase B; Dawes JC; Parmar M; Turner AJ; Tunariu N; Banerjee S; de Bono JS; Banerji U
Ann Oncol; 2018 Sep; 29(9):1918-1925. PubMed ID: 30016392
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8. Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review.
Li X; Guo Z; Liu J; Wei S; Ren D; Chen G; Xu S; Chen J
Thorac Cancer; 2018 Feb; 9(2):316-323. PubMed ID: 29388384
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9. Clinicopathologic and genetic features of primary bronchopulmonary mucoepidermoid carcinoma: the MD Anderson cancer Center experience and comprehensive review of the literature.
Salem A; Bell D; Sepesi B; Papadimitrakopoulou V; El-Naggar A; Moran CA; Kalhor N
Virchows Arch; 2017 Jun; 470(6):619-626. PubMed ID: 28343305
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10. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Lu Y; Day FR; Gustafsson S; Buchkovich ML; Na J; Bataille V; Cousminer DL; Dastani Z; Drong AW; Esko T; Evans DM; Falchi M; Feitosa MF; Ferreira T; Hedman ÅK; Haring R; Hysi PG; Iles MM; Justice AE; Kanoni S; Lagou V; Li R; Li X; Locke A; Lu C; Mägi R; Perry JR; Pers TH; Qi Q; Sanna M; Schmidt EM; Scott WR; Shungin D; Teumer A; Vinkhuyzen AA; Walker RW; Westra HJ; Zhang M; Zhang W; Zhao JH; Zhu Z; Afzal U; Ahluwalia TS; Bakker SJ; Bellis C; Bonnefond A; Borodulin K; Buchman AS; Cederholm T; Choh AC; Choi HJ; Curran JE; de Groot LC; De Jager PL; Dhonukshe-Rutten RA; Enneman AW; Eury E; Evans DS; Forsen T; Friedrich N; Fumeron F; Garcia ME; Gärtner S; Han BG; Havulinna AS; Hayward C; Hernandez D; Hillege H; Ittermann T; Kent JW; Kolcic I; Laatikainen T; Lahti J; Mateo Leach I; Lee CG; Lee JY; Liu T; Liu Y; Lobbens S; Loh M; Lyytikäinen LP; Medina-Gomez C; Michaëlsson K; Nalls MA; Nielson CM; Oozageer L; Pascoe L; Paternoster L; Polašek O; Ripatti S; Sarzynski MA; Shin CS; Narančić NS; Spira D; Srikanth P; Steinhagen-Thiessen E; Sung YJ; Swart KM; Taittonen L; Tanaka T; Tikkanen E; van der Velde N; van Schoor NM; Verweij N; Wright AF; Yu L; Zmuda JM; Eklund N; Forrester T; Grarup N; Jackson AU; Kristiansson K; Kuulasmaa T; Kuusisto J; Lichtner P; Luan J; Mahajan A; Männistö S; Palmer CD; Ried JS; Scott RA; Stancáková A; Wagner PJ; Demirkan A; Döring A; Gudnason V; Kiel DP; Kühnel B; Mangino M; Mcknight B; Menni C; O'Connell JR; Oostra BA; Shuldiner AR; Song K; Vandenput L; van Duijn CM; Vollenweider P; White CC; Boehnke M; Boettcher Y; Cooper RS; Forouhi NG; Gieger C; Grallert H; Hingorani A; Jørgensen T; Jousilahti P; Kivimaki M; Kumari M; Laakso M; Langenberg C; Linneberg A; Luke A; Mckenzie CA; Palotie A; Pedersen O; Peters A; Strauch K; Tayo BO; Wareham NJ; Bennett DA; Bertram L; Blangero J; Blüher M; Bouchard C; Campbell H; Cho NH; Cummings SR; Czerwinski SA; Demuth I; Eckardt R; Eriksson JG; Ferrucci L; Franco OH; Froguel P; Gansevoort RT; Hansen T; Harris TB; Hastie N; Heliövaara M; Hofman A; Jordan JM; Jula A; Kähönen M; Kajantie E; Knekt PB; Koskinen S; Kovacs P; Lehtimäki T; Lind L; Liu Y; Orwoll ES; Osmond C; Perola M; Pérusse L; Raitakari OT; Rankinen T; Rao DC; Rice TK; Rivadeneira F; Rudan I; Salomaa V; Sørensen TI; Stumvoll M; Tönjes A; Towne B; Tranah GJ; Tremblay A; Uitterlinden AG; van der Harst P; Vartiainen E; Viikari JS; Vitart V; Vohl MC; Völzke H; Walker M; Wallaschofski H; Wild S; Wilson JF; Yengo L; Bishop DT; Borecki IB; Chambers JC; Cupples LA; Dehghan A; Deloukas P; Fatemifar G; Fox C; Furey TS; Franke L; Han J; Hunter DJ; Karjalainen J; Karpe F; Kaplan RC; Kooner JS; McCarthy MI; Murabito JM; Morris AP; Bishop JA; North KE; Ohlsson C; Ong KK; Prokopenko I; Richards JB; Schadt EE; Spector TD; Widén E; Willer CJ; Yang J; Ingelsson E; Mohlke KL; Hirschhorn JN; Pospisilik JA; Zillikens MC; Lindgren C; Kilpeläinen TO; Loos RJ
Nat Commun; 2016 Feb; 7():10495. PubMed ID: 26833246
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11. [Pulmonary Mucoepidermoid Carcinoma--A Case Report].
Yokouchi H; Miyazaki M; Miyamoto T; Minami T; Tsuji F; Murata K; Ohishi K
Gan To Kagaku Ryoho; 2015 Nov; 42(12):1830-2. PubMed ID: 26805187
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12. Pathological complete response to gefitinib in a 10-year-old boy with EGFR-negative pulmonary mucoepidermoid carcinoma: a case report and literature review.
Li S; Zhang Z; Tang H; He Z; Gao Y; Ma W; Chang Y; Wei B; Ma J; Liu K; Ma Z; Wang Q
Clin Respir J; 2017 May; 11(3):346-351. PubMed ID: 26148572
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13. Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer.
Faber AC; Farago AF; Costa C; Dastur A; Gomez-Caraballo M; Robbins R; Wagner BL; Rideout WM; Jakubik CT; Ham J; Edelman EJ; Ebi H; Yeo AT; Hata AN; Song Y; Patel NU; March RJ; Tam AT; Milano RJ; Boisvert JL; Hicks MA; Elmiligy S; Malstrom SE; Rivera MN; Harada H; Windle BE; Ramaswamy S; Benes CH; Jacks T; Engelman JA
Proc Natl Acad Sci U S A; 2015 Mar; 112(11):E1288-96. PubMed ID: 25737542
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14. Role of LKB1-crtc1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer.
Cao C; Gao R; Zhang M; Amelio AL; Fallahi M; Chen Z; Gu Y; Hu C; Welsh EA; Engel BE; Haura EB; Cress WD; Wu L; Zajac-Kaye M; Kaye FJ
J Natl Cancer Inst; 2015 Jan; 107(1):358. PubMed ID: 25465874
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15. Investigational drug MLN0128, a novel torc1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models.
Gökmen-Polar Y; Liu Y; Toroni RA; Sanders KL; Mehta R; Badve S; Rommel C; Sledge GW
Breast Cancer Res Treat; 2012 Dec; 136(3):673-82. PubMed ID: 23085766
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16. The crtc1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
Feng Y; Wang Y; Wang Z; Fang Z; Li F; Gao Y; Liu H; Xiao T; Li F; Zhou Y; Zhai Q; Liu X; Sun Y; Bardeesy N; Wong KK; Chen H; Xiong ZQ; Ji H
Cancer Res; 2012 Dec; 72(24):6502-11. PubMed ID: 23074285
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17. crtc1-MAML2 gene fusion in mucoepidermoid carcinoma of the lacrimal gland.
Von Holstein SL; Fehr A; Heegaard S; Therkildsen MH; Stenman G
Oncol Rep; 2012 May; 27(5):1413-6. PubMed ID: 22323114
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18. GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway.
Wallin JJ; Edgar KA; Guan J; Berry M; Prior WW; Lee L; Lesnick JD; Lewis C; Nonomiya J; Pang J; Salphati L; Olivero AG; Sutherlin DP; O'Brien C; Spoerke JM; Patel S; Lensun L; Kassees R; Ross L; Lackner MR; Sampath D; Belvin M; Friedman LS
Mol Cancer Ther; 2011 Dec; 10(12):2426-36. PubMed ID: 21998291
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19. Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer.
Yang X; Turke AB; Qi J; Song Y; Rexer BN; Miller TW; Jänne PA; Arteaga CL; Cantley LC; Engelman JA; Asara JM
Cancer Res; 2011 Sep; 71(18):5965-75. PubMed ID: 21775521
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20. Enhanced activity of the CREB co-activator crtc1 in LKB1 null lung cancer.
Komiya T; Coxon A; Park Y; Chen WD; Zajac-Kaye M; Meltzer P; Karpova T; Kaye FJ
Oncogene; 2010 Mar; 29(11):1672-80. PubMed ID: 20010869
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