BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND EML4, ENSG00000143924, 27436
837 results:

  • 1. Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce lung cancer Regrowth after Crizotinib Treatment.
    Horvat NK; Chocarro S; Marques O; Bauer TA; Qiu R; Diaz-Jimenez A; Helm B; Chen Y; Sawall S; Sparla R; Su L; Klingmüller U; Barz M; Hentze MW; Sotillo R; Muckenthaler MU
    ACS Nano; 2024 Apr; 18(17):11025-11041. PubMed ID: 38626916
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. [A case of crizotinib-associated renal cysts].
    Quan LL; Huang P; Liang YC; Chen FW; Liu SB; Xin WW
    Zhonghua Jie He He Hu Xi Za Zhi; 2024 Apr; 47(4):356-359. PubMed ID: 38599812
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Impact of Tumor-intrinsic Molecular Features on Survival and Acquired Tyrosine Kinase Inhibitor Resistance in ALK-positive NSCLC.
    Nakazawa M; Harada G; Ghanem P; Bubie A; Kiedrowski LA; Murray JC; Marrone KA; Scott SC; Houseknecht S; Falcon CJ; Evans P; Feliciano J; Hann CL; Ettinger DS; Smith KN; Anagnostou V; Forde PM; Brahmer JR; Levy B; Drilon A; Lam VK
    Cancer Res Commun; 2024 Mar; 4(3):786-795. PubMed ID: 38407352
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Case report: Clinical complete response in advanced ALK-positive lung squamous cell carcinoma: a case study of successful anti-PD-1 immunotherapy post ALK-TKIs failure.
    Yang C; Zeng R; Zha Y; Li Y; Wang T; Zhao R; Li M; Zhang J
    Front Immunol; 2024; 15():1360671. PubMed ID: 38380327
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Expansion of targeted degradation by Gilteritinib-Warheaded PROTACs to ALK fusion proteins.
    Yokoo H; Tsuji G; Inoue T; Naito M; Demizu Y; Ohoka N
    Bioorg Chem; 2024 Apr; 145():107204. PubMed ID: 38377822
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A novel eml4-NTRK3 fusion in lung adenocarcinoma with dramatic response to entrectinib.
    Batra U; Nathany S; Sharma M; Jain P; Mehta A; Bansal A
    J Cancer Res Ther; 2023 Oct; 19(7):2045-2047. PubMed ID: 38376315
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Deterministic reprogramming and signaling activation following targeted therapy in non-small cell lung cancer driven by mutations or oncogenic fusions.
    Rosell R; Pedraz-Valdunciel C; Jain A; Shivamallu C; Aguilar A
    Expert Opin Investig Drugs; 2024 Mar; 33(3):171-182. PubMed ID: 38372666
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Longitudinal plasma proteomic profiling of eml4-ALK positive lung cancer receiving ALK-TKIs therapy.
    Wang S; Hao X; Dai L; Lou N; Fan G; Gao R; Yang M; Xing P; Liu Y; Wang L; Zhang Z; Yao J; Tang L; Shi Y; Han X
    Lung Cancer; 2024 Mar; 189():107503. PubMed ID: 38359741
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Mitoxantrone and abacavir: An ALK protein-targeted in silico proposal for the treatment of non-small cell lung cancer.
    Faya Castillo JE; Zapata Dongo RJ; Wong Chero PA; Infante Varillas SF
    PLoS One; 2024; 19(2):e0295966. PubMed ID: 38319906
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. lung carcinoma with diffuse cysts repeatedly misdiagnosed as pulmonary infections and lymphoid interstitial pneumonia: A case report.
    Li Y; Lu J; Yuan J
    Medicine (Baltimore); 2024 Feb; 103(5):e37002. PubMed ID: 38306516
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. eml4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation.
    Qin Z; Yue M; Tang S; Wu F; Sun H; Li Y; Zhang Y; Izumi H; Huang H; Wang W; Xue Y; Tong X; Mori S; Taki T; Goto K; Jin Y; Li F; Li FM; Gao Y; Fang Z; Fang Y; Hu L; Yan X; Xu G; Chen H; Kobayashi SS; Ventura A; Wong KK; Zhu X; Chen L; Ren S; Chen LN; Ji H
    J Exp Med; 2024 Mar; 221(3):. PubMed ID: 38284990
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. lung adenocarcinoma with brain metastasis detected dual fusion of LOC399815-ALK and ALK-eml4 in combined treatment of Alectinib and CyberKnife: A case report.
    Li Y; Lu S; Yao P; Huang W; Huang Y; Zhou Y; Yuan Y; Cheng S; Wu F
    Medicine (Baltimore); 2024 Jan; 103(3):e36992. PubMed ID: 38241569
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Left total pneumonectomy performed after alectinib treatment for anaplastic lymphoma kinase-positive lung adenocarcinoma: a case report.
    Wang Z; Shi Y; Zhang P; Chen Y
    Chin Clin Oncol; 2023 Dec; 12(6):70. PubMed ID: 38195077
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Frequency and functional characterization of fusion genes in squamous cell carcinoma of the lung.
    Alidousty C; Becker A; Binot E; Hillmer AM; Merkelbach-Bruse S; Budde B; Bäßmann I; Rappl G; Wolf J; Eich ML; Noh KW; Buettner R; Schultheis AM
    Gene; 2024 Feb; 895():148018. PubMed ID: 37981082
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. eml4-ALK fusion protein in lung cancer cells enhances venous thrombogenicity through the pERK1/2-AP-1-tissue factor axis.
    Su Y; Yi J; Zhang Y; Leng D; Huang X; Shi X; Zhang Y
    J Thromb Thrombolysis; 2024 Jan; 57(1):67-81. PubMed ID: 37940761
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Comparison of gene mutation profile in different lung adenocarcinoma subtypes by targeted next-generation sequencing.
    Zhang S; Dong P; Pan Z; Chen Q; Zhu J; Mao Z
    Med Oncol; 2023 Nov; 40(12):349. PubMed ID: 37935925
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Neoadjuvant Lorlatinib Induces Pathological Complete Response in Advanced ALK-Positive lung cancer: A Case Report.
    Li J; Liu J; Zhang G; Hu W; Wang X; Liu J
    Am J Case Rep; 2023 Nov; 24():e942150. PubMed ID: 37934724
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Transformation of NSCLC to SCLC harboring eml4-ALK fusion with V1180L mutation after alectinib resistance and response to lorlatinib: A case report and literature review.
    Lingling X; Maoxi C; Wei Y; Jieting Z; Yuanyuan Y; Ning X
    Lung Cancer; 2023 Dec; 186():107415. PubMed ID: 37907052
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. A non-small cell lung carcinoma patient responded to crizotinib therapy after alectinib-induced interstitial lung disease.
    Sun W; Zheng J; Zhou J; Zhou J
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2023 Oct; 52(5):583-587. PubMed ID: 37899398
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Non-Small Cell lung cancer: Targetable Variants in Concurrent Tissue and Liquid Biopsy Testing in a North Indian Cohort.
    Paturu R; Lingaiah R; Kumari N; Singh S; Krishnani N; Srivastava S; Siddiqui SH; Nath A
    Asian Pac J Cancer Prev; 2023 Oct; 24(10):3467-3475. PubMed ID: 37898852
    [TBL] [Abstract] [Full Text] [Related]  


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