Terms: = Lung cancer AND ERBB3, c-erbB3, 2065, P21860, p180-ErbB3, c-erbB-3, ErbB-3, MDA-BF-1, HER3, p85-sErbB3, MGC88033, p45-sErbB3, ENSG00000065361, erbB3-S
426 results:
1. DB-1310, an ADC comprised of a novel anti-her3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of her3-positive solid tumors.
Li X; Yao J; Qu C; Luo L; Li B; Zhang Y; Zhu Z; Qiu Y; Hua H
J Transl Med; 2024 Apr; 22(1):362. PubMed ID: 38632563
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2. Translational insights and overall survival in the U31402-A-U102 study of patritumab deruxtecan (her3-DXd) in EGFR-mutated NSCLC.
Yu HA; Baik C; Kim DW; Johnson ML; Hayashi H; Nishio M; Yang JC; Su WC; Gold KA; Koczywas M; Smit EF; Steuer CE; Felip E; Murakami H; Kim SW; Su X; Sato S; Fan PD; Fujimura M; Tanaka Y; Patel P; Sternberg DW; Sellami D; Jänne PA
Ann Oncol; 2024 May; 35(5):437-447. PubMed ID: 38369013
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3. Leucine Zipper Downregulated in cancer-1 Interacts with Clathrin Adaptors to Control Epidermal Growth Factor Receptor (EGFR) Internalization and Gefitinib Response in EGFR-Mutated Non-Small Cell lung cancer.
Huang HN; Hung PF; Chen YP; Lee CH
Int J Mol Sci; 2024 Jan; 25(3):. PubMed ID: 38338651
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4. Targeting her3 to overcome EGFR TKI resistance in NSCLC.
Chen Q; Jia G; Zhang X; Ma W
Front Immunol; 2023; 14():1332057. PubMed ID: 38239350
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5. Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.
Hosni S; Kilian V; Klümper N; Gabbia D; Sieckmann K; Corvino D; Winkler A; Saponaro M; Wörsdörfer K; Schmidt D; Hahn O; Zanotto I; Bertlich M; Toma M; Bald T; Eckstein M; Hölzel M; Geyer M; Ritter M; Wachten D; De Martin S; Alajati A
Cancer Res; 2024 Mar; 84(5):725-740. PubMed ID: 38175774
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6. Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements.
Zhang X; Li L; Gao F; Liu B; Li J; Ren S; Peng S; Qiu W; Pu X; Ye Q
Diagn Pathol; 2024 Jan; 19(1):1. PubMed ID: 38173003
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7. HERTHENA-lung02: phase III study of patritumab deruxtecan in advanced
Mok T; Jänne PA; Nishio M; Novello S; Reck M; Steuer C; Wu YL; Fougeray R; Fan PD; Meng J; Sternberg DW; Esker S; Yu HA
Future Oncol; 2024 May; 20(15):969-980. PubMed ID: 38095056
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8. CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the erbb3/STAT3 signaling pathway.
Liu YN; Tsai MF; Wu SG; Chang TH; Shih JY
Life Sci; 2024 Jan; 336():122345. PubMed ID: 38092140
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9. her3: Toward the Prognostic Significance, Therapeutic Potential, Current Challenges, and Future Therapeutics in Different Types of cancer.
Majumder A
Cells; 2023 Oct; 12(21):. PubMed ID: 37947595
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10. Association of the m
Li Y; Cao J; Wang J; Wu W; Jiang L; Sun X
Cancer; 2024 Feb; 130(3):356-374. PubMed ID: 37861451
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11. Patritumab Deruxtecan (her3-DXd), a Human Epidermal Growth Factor Receptor 3-Directed Antibody-Drug Conjugate, in Patients With Previously Treated Human Epidermal Growth Factor Receptor 3-Expressing Metastatic Breast cancer: A Multicenter, Phase I/II Trial.
Krop IE; Masuda N; Mukohara T; Takahashi S; Nakayama T; Inoue K; Iwata H; Yamamoto Y; Alvarez RH; Toyama T; Takahashi M; Osaki A; Saji S; Sagara Y; O'Shaughnessy J; Ohwada S; Koyama K; Inoue T; Li L; Patel P; Mostillo J; Tanaka Y; Sternberg DW; Sellami D; Yonemori K
J Clin Oncol; 2023 Dec; 41(36):5550-5560. PubMed ID: 37801674
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12. Role of human epidermal growth factor receptor 3 in treatment resistance of anaplastic lymphoma kinase translocated non-small cell lung cancer.
Honkanen TJ; Luukkainen MEK; Koivunen JP
Cancer Biol Ther; 2023 Dec; 24(1):2256906. PubMed ID: 37722715
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13. Cellular responses after (neratinib plus pemetrexed) exposure in NSCLC cells.
Booth L; Poklepovic A; Hancock JF; Dent P
Anticancer Drugs; 2023 Oct; 34(9):1025-1034. PubMed ID: 37703296
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14. HERTHENA-lung01, a Phase II Trial of Patritumab Deruxtecan (her3-DXd) in Epidermal Growth Factor Receptor-Mutated Non-Small-Cell lung cancer After Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and Platinum-Based Chemotherapy.
Yu HA; Goto Y; Hayashi H; Felip E; Chih-Hsin Yang J; Reck M; Yoh K; Lee SH; Paz-Ares L; Besse B; Bironzo P; Kim DW; Johnson ML; Wu YL; John T; Kao S; Kozuki T; Massarelli E; Patel J; Smit E; Reckamp KL; Dong Q; Shrestha P; Fan PD; Patel P; Sporchia A; Sternberg DW; Sellami D; Jänne PA
J Clin Oncol; 2023 Dec; 41(35):5363-5375. PubMed ID: 37689979
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15. HER4 and EGFR Activate Cell Signaling in NRG1 Fusion-Driven cancers: Implications for HER2-her3-specific Versus Pan-HER Targeting Strategies.
Udagawa H; Nilsson MB; Robichaux JP; He J; Poteete A; Jiang H; Heeke S; Elamin YY; Shibata Y; Matsumoto S; Yoh K; Okazaki S; Masuko T; Odintsov I; Somwar R; Ladanyi M; Goto K; Heymach JV
J Thorac Oncol; 2024 Jan; 19(1):106-118. PubMed ID: 37678511
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16. Identification of Potent Inhibitors Targeting EGFR and her3 for Effective Treatment of Chemoresistance in Non-Small Cell lung cancer.
Dera AA; Zaib S; Areeba ; Hussain N; Rana N; Javed H; Khan I
Molecules; 2023 Jun; 28(12):. PubMed ID: 37375404
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17. Afatinib for the Treatment of NSCLC with Uncommon EGFR Mutations: A Narrative Review.
Jiang Y; Fang X; Xiang Y; Fang T; Liu J; Lu K
Curr Oncol; 2023 May; 30(6):5337-5349. PubMed ID: 37366888
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18. Clinicopathological Characteristics of NRG1 Fusion-Positive Solid Tumors in Korean Patients.
Cha YJ; Lee C; Joo B; Kim KA; Lee CK; Shim HS
Cancer Res Treat; 2023 Oct; 55(4):1087-1095. PubMed ID: 37321274
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19. Keeping It in the Family: her3 as a Target in Brain Metastases.
Kabraji S; Lin NU
Clin Cancer Res; 2023 Aug; 29(16):2961-2963. PubMed ID: 37306554
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20. AMT-562, a Novel her3-targeting Antibody-Drug Conjugate, Demonstrates a Potential to Broaden Therapeutic Opportunities for her3-expressing Tumors.
Weng W; Meng T; Pu J; Ma L; Shen Y; Wang Z; Pan R; Wang M; Chen C; Wang L; Zhang J; Zhou B; Shao S; Qian Y; Liu S; Hu W; Meng X
Mol Cancer Ther; 2023 Sep; 22(9):1013-1027. PubMed ID: 37302522
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