BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND ERBB3, c-erbB3, 2065, P21860, p180-ErbB3, c-erbB-3, ErbB-3, MDA-BF-1, HER3, p85-sErbB3, MGC88033, p45-sErbB3, ENSG00000065361, erbB3-S AND Treatment
198 results:

  • 1. DB-1310, an ADC comprised of a novel anti-her3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of her3-positive solid tumors.
    Li X; Yao J; Qu C; Luo L; Li B; Zhang Y; Zhu Z; Qiu Y; Hua H
    J Transl Med; 2024 Apr; 22(1):362. PubMed ID: 38632563
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Translational insights and overall survival in the U31402-A-U102 study of patritumab deruxtecan (her3-DXd) in EGFR-mutated NSCLC.
    Yu HA; Baik C; Kim DW; Johnson ML; Hayashi H; Nishio M; Yang JC; Su WC; Gold KA; Koczywas M; Smit EF; Steuer CE; Felip E; Murakami H; Kim SW; Su X; Sato S; Fan PD; Fujimura M; Tanaka Y; Patel P; Sternberg DW; Sellami D; Jänne PA
    Ann Oncol; 2024 May; 35(5):437-447. PubMed ID: 38369013
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Leucine Zipper Downregulated in cancer-1 Interacts with Clathrin Adaptors to Control Epidermal Growth Factor Receptor (EGFR) Internalization and Gefitinib Response in EGFR-Mutated Non-Small Cell lung cancer.
    Huang HN; Hung PF; Chen YP; Lee CH
    Int J Mol Sci; 2024 Jan; 25(3):. PubMed ID: 38338651
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Targeting her3 to overcome EGFR TKI resistance in NSCLC.
    Chen Q; Jia G; Zhang X; Ma W
    Front Immunol; 2023; 14():1332057. PubMed ID: 38239350
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.
    Hosni S; Kilian V; Klümper N; Gabbia D; Sieckmann K; Corvino D; Winkler A; Saponaro M; Wörsdörfer K; Schmidt D; Hahn O; Zanotto I; Bertlich M; Toma M; Bald T; Eckstein M; Hölzel M; Geyer M; Ritter M; Wachten D; De Martin S; Alajati A
    Cancer Res; 2024 Mar; 84(5):725-740. PubMed ID: 38175774
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements.
    Zhang X; Li L; Gao F; Liu B; Li J; Ren S; Peng S; Qiu W; Pu X; Ye Q
    Diagn Pathol; 2024 Jan; 19(1):1. PubMed ID: 38173003
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. HERTHENA-lung02: phase III study of patritumab deruxtecan in advanced
    Mok T; Jänne PA; Nishio M; Novello S; Reck M; Steuer C; Wu YL; Fougeray R; Fan PD; Meng J; Sternberg DW; Esker S; Yu HA
    Future Oncol; 2024 May; 20(15):969-980. PubMed ID: 38095056
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the erbb3/STAT3 signaling pathway.
    Liu YN; Tsai MF; Wu SG; Chang TH; Shih JY
    Life Sci; 2024 Jan; 336():122345. PubMed ID: 38092140
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. her3: Toward the Prognostic Significance, Therapeutic Potential, Current Challenges, and Future Therapeutics in Different Types of cancer.
    Majumder A
    Cells; 2023 Oct; 12(21):. PubMed ID: 37947595
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Patritumab Deruxtecan (her3-DXd), a Human Epidermal Growth Factor Receptor 3-Directed Antibody-Drug Conjugate, in Patients With Previously Treated Human Epidermal Growth Factor Receptor 3-Expressing Metastatic Breast cancer: A Multicenter, Phase I/II Trial.
    Krop IE; Masuda N; Mukohara T; Takahashi S; Nakayama T; Inoue K; Iwata H; Yamamoto Y; Alvarez RH; Toyama T; Takahashi M; Osaki A; Saji S; Sagara Y; O'Shaughnessy J; Ohwada S; Koyama K; Inoue T; Li L; Patel P; Mostillo J; Tanaka Y; Sternberg DW; Sellami D; Yonemori K
    J Clin Oncol; 2023 Dec; 41(36):5550-5560. PubMed ID: 37801674
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Role of human epidermal growth factor receptor 3 in treatment resistance of anaplastic lymphoma kinase translocated non-small cell lung cancer.
    Honkanen TJ; Luukkainen MEK; Koivunen JP
    Cancer Biol Ther; 2023 Dec; 24(1):2256906. PubMed ID: 37722715
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Identification of Potent Inhibitors Targeting EGFR and her3 for Effective treatment of Chemoresistance in Non-Small Cell lung cancer.
    Dera AA; Zaib S; Areeba ; Hussain N; Rana N; Javed H; Khan I
    Molecules; 2023 Jun; 28(12):. PubMed ID: 37375404
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Afatinib for the treatment of NSCLC with Uncommon EGFR Mutations: A Narrative Review.
    Jiang Y; Fang X; Xiang Y; Fang T; Liu J; Lu K
    Curr Oncol; 2023 May; 30(6):5337-5349. PubMed ID: 37366888
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. HERTHENA-lung01: a phase II study of patritumab deruxtecan (her3-DXd) in previously treated metastatic
    Yu HA; Yang JC; Hayashi H; Goto Y; Felip E; Reck M; Vigliotti M; Dong Q; Cantero F; Fan PD; Kanai M; Sternberg DW; Jänne PA
    Future Oncol; 2023 Jun; 19(19):1319-1329. PubMed ID: 37212796
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Downregulation of circ_PLXND1 inhibits tumorigenesis of non-small cell lung carcinoma via miR-1287-5p/erbb3 axis.
    Wu J; Liu C; Yu G
    Thorac Cancer; 2023 Jun; 14(17):1543-1555. PubMed ID: 37073425
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Frequent Overexpression of her3 in Brain Metastases from Breast and lung cancer.
    Tomasich E; Steindl A; Paiato C; Hatziioannou T; Kleinberger M; Berchtold L; Puhr R; Hainfellner JA; Müllauer L; Widhalm G; Eckert F; Bartsch R; Heller G; Preusser M; Berghoff AS
    Clin Cancer Res; 2023 Aug; 29(16):3225-3236. PubMed ID: 37036472
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. ROS1 as a possible prognostic biomarker of cervical adenocarcinoma: An exploratory analysis with next-generation sequencing.
    Machida H; Matsuo K; Tanaka M; Kitatani K; Takase A; Yokoyama K; Kajiwara H; Yasaka M; Ikeda M; Yoshida H; Hirasawa T; Mikami M
    Gynecol Oncol; 2023 Apr; 171():59-66. PubMed ID: 36804622
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Targeting her3 for cancer treatment: a new horizon for an old target.
    Uliano J; Corvaja C; Curigliano G; Tarantino P
    ESMO Open; 2023 Feb; 8(1):100790. PubMed ID: 36764093
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Antibody-Exatecan Conjugates with a Novel Self-immolative Moiety Overcome Resistance in Colon and lung cancer.
    Weng W; Meng T; Zhao Q; Shen Y; Fu G; Shi J; Zhang Y; Wang Z; Wang M; Pan R; Ma L; Chen C; Wang L; Zhou B; Zhang H; Pu J; Zhang J; Hu YP; Hua G; Qian Y; Liu SH; Hu W; Meng X
    Cancer Discov; 2023 Apr; 13(4):950-973. PubMed ID: 36693125
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Targeting the EGF receptor family in non-small cell lung cancer-increased complexity and future perspectives.
    Boch T; Köhler J; Janning M; Loges S
    Cancer Biol Med; 2022 Dec; 19(11):1543-64. PubMed ID: 36476337
    [TBL] [Abstract] [Full Text] [Related]  


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