Terms: = Lung cancer AND EZH2, ENX-1, 2146, ENSG00000106462, Q15910, MGC9169 AND Treatment
111 results:
1. PROTAC ezh2 degrader-1 overcomes the resistance of podophyllotoxin derivatives in refractory small cell lung cancer with leptomeningeal metastasis.
Shi MX; Ding X; Tang L; Cao WJ; Su B; Zhang J
BMC Cancer; 2024 Apr; 24(1):504. PubMed ID: 38644473
[TBL] [Abstract] [Full Text] [Related]
2. treatment of Thoracic SMARCA4-Deficient Undifferentiated Tumors: Where We Are and Where We Will Go.
Longo V; Catino A; Montrone M; Montagna ES; Pesola F; Marech I; Pizzutilo P; Nardone A; Perrone A; Gesualdo M; Galetta D
Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542211
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3. ezh2 Inhibition Promotes Tumor Immunogenicity in lung Squamous Cell Carcinomas.
DuCote TJ; Song X; Naughton KJ; Chen F; Plaugher DR; Childress AR; Gellert AR; Skaggs EM; Qu X; Liu J; Liu J; Li F; Wong KK; Brainson CF
Cancer Res Commun; 2024 Feb; 4(2):388-403. PubMed ID: 38265267
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4. Combined Inhibition of ezh2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma.
Badhai J; Landman N; Pandey GK; Song JY; Hulsman D; Krijgsman O; Chandrasekaran G; Berns A; van Lohuizen M
Cancer Res Commun; 2024 Jan; 4(1):18-27. PubMed ID: 38054839
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5. Long Non-coding RNA
Endo I; Amatya VJ; Kushitani K; Nakagiri T; Aoe K; Takeshima Y
Anticancer Res; 2023 Dec; 43(12):5367-5376. PubMed ID: 38030172
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6. Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells.
Wu DD; Lau ATY; Xu YM; Reinders-Luinge M; Koncz M; Kiss A; Timens W; Rots MG; Hylkema MN
Epigenetics; 2023 Dec; 18(1):2175522. PubMed ID: 38016026
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7. Conformationally constrained potent inhibitors for enhancer of zeste homolog 2 (ezh2).
Xu X; Chen J; Wang G; Zhang X; Li Q; Zhou X; Guo F; Li M
Bioorg Med Chem Lett; 2024 Jan; 97():129558. PubMed ID: 37956762
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8. Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in lung Adenocarcinoma.
Saggese P; Pandey A; Alcaraz M; Fung E; Hall A; Yanagawa J; Rodriguez EF; Grogan TR; Giurato G; Nassa G; Salvati A; Shirihai OS; Weisz A; Dubinett SM; Scafoglio C
Cancer Res; 2024 Jan; 84(2):305-327. PubMed ID: 37934116
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9. Brucea javanica oil inhibits tongue squamous cell invasion and metastasis by regulating miR-138-ezh2 pathway.
Jiang L; Zhou J; Wu Y; Zhou L; Zhang C; Zhu J; Fang Z; Shao Y; Wang W
J Stomatol Oral Maxillofac Surg; 2023 Dec; 124(6S):101611. PubMed ID: 37619672
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10. Molecular alterations and potential actionable mutations in peritoneal mesothelioma: a scoping review of high-throughput sequencing studies.
Dietz MV; van Kooten JP; Paats MS; Aerts JGVJ; Verhoef C; Madsen EVE; Dubbink HJ; von der Thüsen JH
ESMO Open; 2023 Aug; 8(4):101600. PubMed ID: 37453150
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11. Dysregulation of SWI/SNF Chromatin Remodelers in NSCLC: Its Influence on cancer Therapies including Immunotherapy.
Shi Y; Shin DS
Biomolecules; 2023 Jun; 13(6):. PubMed ID: 37371564
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12. FZKA reverses gefitinib resistance by regulating ezh2/Snail/EGFR signaling pathway in lung adenocarcinoma.
Tang Q; Xu M; Long S; Yu Y; Ma C; Wang R; Li J; Wang X; Fang F; Han L; Wu W; Wang S
J Ethnopharmacol; 2024 Jan; 318(Pt A):116646. PubMed ID: 37269912
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13. LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer.
Dai J; Qu T; Yin D; Cui Y; Zhang C; Zhang E; Guo R
Cell Death Dis; 2023 May; 14(5):312. PubMed ID: 37156816
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14. LncRNA MALAT1 promotes growth and metastasis of head and neck squamous cell carcinoma by repressing VHL through a non-canonical function of ezh2.
Duan Y; Yue K; Ye B; Chen P; Zhang J; He Q; Wu Y; Lai Q; Li H; Wu Y; Jing C; Wang X
Cell Death Dis; 2023 Feb; 14(2):149. PubMed ID: 36813772
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15. Design, Synthesis, and Biological Evaluation of a Potent Dual ezh2-BRD4 Inhibitor for the treatment of Some Solid Tumors.
Huang N; Liao P; Zuo Y; Zhang L; Jiang R
J Med Chem; 2023 Feb; 66(4):2646-2662. PubMed ID: 36774555
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16. The pharmacological and biological importance of ezh2 signaling in lung cancer.
Entezari M; Taheriazam A; Paskeh MDA; Sabouni E; Zandieh MA; Aboutalebi M; Kakavand A; Rezaei S; Hejazi ES; Saebfar H; Salimimoghadam S; Mirzaei S; Hashemi M; Samarghandian S
Biomed Pharmacother; 2023 Apr; 160():114313. PubMed ID: 36738498
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17. MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer.
Kitajima S; Tani T; Springer BF; Campisi M; Osaki T; Haratani K; Chen M; Knelson EH; Mahadevan NR; Ritter J; Yoshida R; Köhler J; Ogino A; Nozawa RS; Sundararaman SK; Thai TC; Homme M; Piel B; Kivlehan S; Obua BN; Purcell C; Yajima M; Barbie TU; Lizotte PH; Jänne PA; Paweletz CP; Gokhale PC; Barbie DA
Cancer Cell; 2022 Oct; 40(10):1128-1144.e8. PubMed ID: 36150391
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18. The role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting ezh2 and regulating FBP1 expression.
Chen Z; Tang W; Zhou Y; He Z
Biol Direct; 2022 Sep; 17(1):23. PubMed ID: 36050791
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19. m6A methyltransferase METTL3-induced lncRNA SNHG17 promotes lung adenocarcinoma gefitinib resistance by epigenetically repressing LATS2 expression.
Zhang H; Wang SQ; Wang L; Lin H; Zhu JB; Chen R; Li LF; Cheng YD; Duan CJ; Zhang CF
Cell Death Dis; 2022 Jul; 13(7):657. PubMed ID: 35902569
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20. A nucleus-targeting peptide antagonist towards ezh2 displays therapeutic efficacy for lung cancer.
Jiang M; Fang X; Ma L; Liu M; Chen M; Liu J; Yang Y; Wang C
Int J Pharm; 2022 Jun; 622():121894. PubMed ID: 35680109
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