Terms: = Lung cancer AND JAK2, ENSG00000096968, O60674, JTK10, 3717 AND Treatment
122 results:
1. A coumarin-furoxan hybrid as novel nitric oxide donor induced cell apoptosis and ferroptosis in NSCLC by promoting S-nitrosylation of STAT3 and negative regulation of jak2-STAT3 pathway.
Cao F; Li M; Wang W; Yi Y; Chen Y; Liu H
Biochem Pharmacol; 2024 Apr; 222():116068. PubMed ID: 38387529
[TBL] [Abstract] [Full Text] [Related]
2. SOCS2 inhibits hepatoblastoma metastasis via downregulation of the jak2/STAT5 signal pathway.
Lv Y; Xie X; Zou G; Kong M; Yang J; Chen J; Xiang B
Sci Rep; 2023 Dec; 13(1):21814. PubMed ID: 38071211
[TBL] [Abstract] [Full Text] [Related]
3. Identifying survival of pan-cancer patients under immunotherapy using genomic mutation signature with large sample cohorts.
Zhang L; Wang Y; Wang L; Wang M; Li S; He J; Ji J; Li K; Cao L
J Mol Med (Berl); 2024 Jan; 102(1):69-79. PubMed ID: 37978056
[TBL] [Abstract] [Full Text] [Related]
4. Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in jak2V617F myeloproliferative neoplasms.
Guy A; Garcia G; Gourdou-Latyszenok V; Wolff-Trombini L; Josserand L; Kimmerlin Q; Favre S; Kilani B; Marty C; Boulaftali Y; Labrouche-Colomer S; Mansier O; James C
J Thromb Haemost; 2024 Jan; 22(1):172-187. PubMed ID: 37678548
[TBL] [Abstract] [Full Text] [Related]
5. JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
Zhang C; Sun Q; Zhao J; Jiang N; Hao Y; Luo J; Karim S; Wu L; de Perrot M; Peng C; Zhao X
Mol Carcinog; 2023 Dec; 62(12):1888-1901. PubMed ID: 37642305
[TBL] [Abstract] [Full Text] [Related]
6. Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer.
Jia T; Miao R; Zhang J; Zhu H; Zhang C; Zeng L; Zhao Y; Cheng W; Shao J
Bioorg Med Chem; 2023 Aug; 91():117384. PubMed ID: 37356356
[TBL] [Abstract] [Full Text] [Related]
7. Resveratrol Loaded by Folate-Modified Liposomes Inhibits Osteosarcoma Growth and lung Metastasis via Regulating jak2/STAT3 Pathway.
Zhu WT; Zeng XF; Yang H; Jia ML; Zhang W; Liu W; Liu SY
Int J Nanomedicine; 2023; 18():2677-2691. PubMed ID: 37228445
[TBL] [Abstract] [Full Text] [Related]
8. Cardiovascular Toxicities Associated with Anaplastic Lymphoma Kinase Inhibitors: A Disproportionality Analysis of the WHO Pharmacovigilance Database (VigiBase).
Niimura T; Miyata K; Hamano H; Nounin Y; Unten H; Yoshino M; Mitsuboshi S; Aizawa F; Yagi K; Koyama T; Goda M; Kanda Y; Izawa-Ishizawa Y; Zamami Y; Ishizawa K
Drug Saf; 2023 Jun; 46(6):545-552. PubMed ID: 37106270
[TBL] [Abstract] [Full Text] [Related]
9. Congenital peribronchial myofibroblastic tumor (CPMT): a case report with long term follow-up and next-generation sequencing (NGS).
Zhou P; Li S; Wang W; Tang Y; Jiang L
BMC Pediatr; 2023 Apr; 23(1):184. PubMed ID: 37081446
[TBL] [Abstract] [Full Text] [Related]
10. A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/jak2/STAT3 signaling pathway in lung adenocarcinoma.
Liang Q; Gong M; Zou JH; Luo MY; Jiang LL; Wang C; Shen NX; Zhang MC; Xu L; Lei HM; Zhang KR; Zhang R; Zhuang G; Zhu L; Chen HZ; Zhou L; Shen Y
Drug Resist Updat; 2023 May; 68():100957. PubMed ID: 36990047
[TBL] [Abstract] [Full Text] [Related]
11. Triptolide reduces PD-L1 through the EGFR and IFN-γ/IRF1 dual signaling pathways.
Xie Y; Ding J; Gao J; Zhang J; Cen S; Zhou J
Int Immunopharmacol; 2023 May; 118():109993. PubMed ID: 36931170
[TBL] [Abstract] [Full Text] [Related]
12. Anemoside A3 Inhibits Macrophage M2-Like Polarization to Prevent Triple-Negative Breast cancer Metastasis.
Liu P; Liu Y; Chen L; Fan Z; Luo Y; Cui Y
Molecules; 2023 Feb; 28(4):. PubMed ID: 36838599
[TBL] [Abstract] [Full Text] [Related]
13. Exogenous Thymosin Beta 4 Suppresses IPF-lung cancer in Mice: Possibly Associated with Its Inhibitory Effect on the jak2/STAT3 Signaling Pathway.
Yu R; Gao D; Bao J; Sun R; Cui M; Mao Y; Li K; Hu E; Zhai Y; Liu Y; Gao Y; Xiao T; Zhou H; Yang C; Xu J
Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835236
[TBL] [Abstract] [Full Text] [Related]
14. Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
Hong L; Aminu M; Li S; Lu X; Petranovic M; Saad MB; Chen P; Qin K; Varghese S; Rinsurongkawong W; Rinsurongkawong V; Spelman A; Elamin YY; Negrao MV; Skoulidis F; Gay CM; Cascone T; Gandhi SJ; Lin SH; Lee PP; Carter BW; Wu CC; Antonoff MB; Sepesi B; Lewis J; Gibbons DL; Vaporciyan AA; Le X; Jack Lee J; Roy-Chowdhuri S; Routbort MJ; Gainor JF; Heymach JV; Lou Y; Wu J; Zhang J; Vokes NI
Nat Commun; 2023 Feb; 14(1):695. PubMed ID: 36755027
[TBL] [Abstract] [Full Text] [Related]
15. Telocinobufagin inhibits osteosarcoma growth and metastasis by inhibiting the jak2/STAT3 signaling pathway.
Ma X; Xu W; Jin X; Mu H; Wang Z; Hua Y; Cai Z; Zhang T
Eur J Pharmacol; 2023 Mar; 942():175529. PubMed ID: 36690054
[TBL] [Abstract] [Full Text] [Related]
16. Ubenimex Combined with Pemetrexed Upregulates SOCS1 to Inhibit lung Adenocarcinoma Progression via the jak2-STAT3 Signaling Pathway.
Chen Q; Wu B; Ge P; Zhang P; Chen X
Dis Markers; 2022; 2022():5614939. PubMed ID: 35789603
[TBL] [Abstract] [Full Text] [Related]
17. Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of jak2 Via the jak2-STAT3-PDL1.
Jing D; Wu W; Chen X; Xiao H; Zhang Z; Chen F; Zhang Z; Liu J; Shao Z; Pu F
Pharmacol Res; 2022 Aug; 182():106287. PubMed ID: 35671921
[TBL] [Abstract] [Full Text] [Related]
18. Role of chemokine-mediated angiogenesis in resistance towards crizotinib and its reversal by anlotinib in EML4-ALK positive NSCLC.
Wang S; Lou N; Luo R; Hao X; Liu Y; Wang L; Shi Y; Han X
J Transl Med; 2022 May; 20(1):248. PubMed ID: 35642002
[TBL] [Abstract] [Full Text] [Related]
19. TGF-β1/SH2B3 axis regulates anoikis resistance and EMT of lung cancer cells by modulating jak2/STAT3 and SHP2/Grb2 signaling pathways.
Wang LN; Zhang ZT; Wang L; Wei HX; Zhang T; Zhang LM; Lin H; Zhang H; Wang SQ
Cell Death Dis; 2022 May; 13(5):472. PubMed ID: 35589677
[TBL] [Abstract] [Full Text] [Related]
20. Gene expression profile of high PD-L1 non-small cell lung cancers refractory to pembrolizumab.
Talb J; Takam Kamga P; Mayenga M; Costantini A; Julié C; Dumenil C; Dumoulin J; Ouaknine J; Giraud V; Dujon C; Azarian R; Glaser C; Emile JF; Giroux Leprieur E
Cancer Immunol Immunother; 2022 Nov; 71(11):2791-2799. PubMed ID: 35435450
[TBL] [Abstract] [Full Text] [Related]
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