Terms: = Lung cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132 AND Prognosis
58 results:
1. Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in
Pillai R; LeBoeuf SE; Hao Y; New C; Blum JLE; Rashidfarrokhi A; Huang SM; Bahamon C; Wu WL; Karadal-Ferrena B; Herrera A; Ivanova E; Cross M; Bossowski JP; Ding H; Hayashi M; Rajalingam S; Karakousi T; Sayin VI; Khanna KM; Wong KK; Wild R; Tsirigos A; Poirier JT; Rudin CM; Davidson SM; Koralov SB; Papagiannakopoulos T
Sci Adv; 2024 Mar; 10(13):eadm9859. PubMed ID: 38536921
[TBL] [Abstract] [Full Text] [Related]
2. keap1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC.
Li J; Shi D; Li S; Shi X; Liu Y; Zhang Y; Wang G; Zhang C; Xia T; Piao HL; Liu HX
Cell Death Dis; 2024 Feb; 15(2):175. PubMed ID: 38413563
[TBL] [Abstract] [Full Text] [Related]
3. The prognostic impact of KRAS, TP53, STK11 and keap1 mutations and their influence on the NLR in NSCLC patients treated with immunotherapy.
Proulx-Rocray F; Routy B; Nassabein R; Belkaid W; Tran-Thanh D; Malo J; Tonneau M; Ouarzadi OE; Florescu M; Tehfe M; Blais N
Cancer Treat Res Commun; 2023; 37():100767. PubMed ID: 37832364
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4.
Lu J; Ding Y; Zhang W; Qi Y; Zhou J; Xu N; Zhang Y; Xie W
Cells; 2023 Apr; 12(9):. PubMed ID: 37174639
[TBL] [Abstract] [Full Text] [Related]
5. Machine learning-based immune phenotypes correlate with STK11/keap1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial.
Rakaee M; Andersen S; Giannikou K; Paulsen EE; Kilvaer TK; Busund LR; Berg T; Richardsen E; Lombardi AP; Adib E; Pedersen MI; Tafavvoghi M; Wahl SGF; Petersen RH; Bondgaard AL; Yde CW; Baudet C; Licht P; Lund-Iversen M; Grønberg BH; Fjellbirkeland L; Helland Å; Pøhl M; Kwiatkowski DJ; Donnem T
Ann Oncol; 2023 Jul; 34(7):578-588. PubMed ID: 37100205
[TBL] [Abstract] [Full Text] [Related]
6. Long-Term Outcomes and Molecular Correlates of Sotorasib Efficacy in Patients With Pretreated
Dy GK; Govindan R; Velcheti V; Falchook GS; Italiano A; Wolf J; Sacher AG; Takahashi T; Ramalingam SS; Dooms C; Kim DW; Addeo A; Desai J; Schuler M; Tomasini P; Hong DS; Lito P; Tran Q; Jones S; Anderson A; Hindoyan A; Snyder W; Skoulidis F; Li BT
J Clin Oncol; 2023 Jun; 41(18):3311-3317. PubMed ID: 37098232
[No Abstract] [Full Text] [Related]
7. Overall survival in patients with advanced non-small cell lung cancer with KRAS G12C mutation with or without STK11 and/or keap1 mutations in a real-world setting.
Julian C; Pal N; Gershon A; Evangelista M; Purkey H; Lambert P; Shi Z; Zhang Q
BMC Cancer; 2023 Apr; 23(1):352. PubMed ID: 37069542
[TBL] [Abstract] [Full Text] [Related]
8. Machine learning reveals two heterogeneous subtypes to assist immune therapy based on lipid metabolism in lung adenocarcinoma.
Gu X; Wei S; Li Z; Xu H
Front Immunol; 2022; 13():1022149. PubMed ID: 36238302
[TBL] [Abstract] [Full Text] [Related]
9. Transcription factor Nrf2 binds to circRNAPIBF1 to regulate SOD2 in lung adenocarcinoma progression.
Zhang Z; Chen Q; Huang C; Rao D; Sang C; Zhu S; Gu L; Xie C; Tang Z; Xu X
Mol Carcinog; 2022 Dec; 61(12):1161-1176. PubMed ID: 36193777
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10. Survival Outcomes and Treatment Patterns in Patients With NFE2L2 and/or keap1 Mutation-Positive Advanced Squamous Cell NSCLC Using a Real-World Clinico-Genomic Database.
Wu Y; Yin Y; Crossland V; Vincent S; Paik PK; Lineberry N; Faller DV
Clin Lung Cancer; 2022 Sep; 23(6):487-497. PubMed ID: 35705448
[TBL] [Abstract] [Full Text] [Related]
11. TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling.
Liu W; Zhao Y; Wang G; Feng S; Ge X; Ye W; Wang Z; Zhu Y; Cai W; Bai J; Zhou X
Redox Biol; 2022 Jul; 53():102344. PubMed ID: 35636015
[TBL] [Abstract] [Full Text] [Related]
12. E3 ligase TRIM15 facilitates non-small cell lung cancer progression through mediating keap1-Nrf2 signaling pathway.
Liang M; Wang L; Sun Z; Chen X; Wang H; Qin L; Zhao W; Geng B
Cell Commun Signal; 2022 May; 20(1):62. PubMed ID: 35534896
[TBL] [Abstract] [Full Text] [Related]
13. Deciphering the tumor microenvironment cell-infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC.
Chen H; Zhang T; Zhang Y; Wu H; Fang Z; Liu Y; Chen Y; Wang Z; Jia S; Ji X; Shang L; Du F; Liu J; Lu M; Chong W
JCI Insight; 2022 Jun; 7(12):. PubMed ID: 35511432
[TBL] [Abstract] [Full Text] [Related]
14. The genomic mutational landscape and its correlation with TMB, PD-L1 expression and CD8
Li Y; Shi X; Mao B; Wang L; Wu L; Li J; Jiao S
Lung Cancer; 2022 Apr; 166():161-169. PubMed ID: 35287068
[TBL] [Abstract] [Full Text] [Related]
15. Machine Learning Identifies Pan-cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes.
Li N; Zhan X
Oxid Med Cell Longev; 2022; 2022():8450087. PubMed ID: 35242279
[TBL] [Abstract] [Full Text] [Related]
16. An aging-related signature predicts favorable outcome and immunogenicity in lung adenocarcinoma.
Zhang W; Li Y; Lyu J; Shi F; Kong Y; Sheng C; Wang S; Wang Q
Cancer Sci; 2022 Mar; 113(3):891-903. PubMed ID: 34967077
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17. Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer.
Delgobo M; Gonçalves RM; Delazeri MA; Falchetti M; Zandoná A; Nascimento das Neves R; Almeida K; Fagundes AC; Gelain DP; Fracasso JI; Macêdo GB; Priori L; Bassani N; Bishop AJR; Forcelini CM; Moreira JCF; Zanotto-Filho A
Free Radic Biol Med; 2021 Dec; 177():58-71. PubMed ID: 34673143
[TBL] [Abstract] [Full Text] [Related]
18. Biomarkers of response to checkpoint inhibitors beyond PD-L1 in lung cancer.
Sholl LM
Mod Pathol; 2022 Jan; 35(Suppl 1):66-74. PubMed ID: 34608245
[TBL] [Abstract] [Full Text] [Related]
19. Comprehensive Analysis of TP53 and keap1 Mutations and Their Impact on Survival in Localized- and Advanced-Stage NSCLC.
Saleh MM; Scheffler M; Merkelbach-Bruse S; Scheel AH; Ulmer B; Wolf J; Buettner R
J Thorac Oncol; 2022 Jan; 17(1):76-88. PubMed ID: 34601169
[TBL] [Abstract] [Full Text] [Related]
20. keap1 and TP53 Frame Genomic, Evolutionary, and Immunologic Subtypes of lung Adenocarcinoma With Different Sensitivity to Immunotherapy.
Scalera S; Mazzotta M; Corleone G; Sperati F; Terrenato I; Krasniqi E; Pizzuti L; Barba M; Vici P; Gallo E; Buglioni S; Visca P; Pescarmona E; Marinelli D; De Nicola F; Ciuffreda L; Goeman F; Fanciulli M; Giusti R; Vecchione A; De Maria R; Cappuzzo F; Marchetti P; Ciliberto G; Maugeri-Saccà M
J Thorac Oncol; 2021 Dec; 16(12):2065-2077. PubMed ID: 34450259
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