BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND KMT2C, ENSG00000055609, MLL3, 58508
33 results:

  • 1. Complex Genomic Rearrangement Patterns in Malignant Pleural Mesothelioma due to Environmental Asbestos Exposure.
    Tuncel T; Ak G; Güneş HV; Metintaş M
    J Environ Pathol Toxicol Oncol; 2024; 43(2):13-27. PubMed ID: 38505910
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. CRISPR/Cas9 model of prostate cancer identifies kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression.
    Cai H; Zhang B; Ahrenfeldt J; Joseph JV; Riedel M; Gao Z; Thomsen SK; Christensen DS; Bak RO; Hager H; Vendelbo MH; Gao X; Birkbak N; Thomsen MK
    Nat Commun; 2024 Mar; 15(1):2088. PubMed ID: 38453924
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Genomic profiling of tissue and blood predicts survival outcomes in patients with resected pleural mesothelioma.
    de Miguel-Perez D; Pickering EM; Malapelle U; Grier W; Pepe F; Pisapia P; Russo G; Pinto JA; Russo A; Troncone G; Culligan MJ; Scilla KA; Mehra R; Mohindra P; Arrieta O; Cardona AF; Del Re M; Sachdeva A; Hirsch FR; Wolf A; Friedberg JS; Rolfo C
    Eur J Cancer; 2024 Jan; 196():113457. PubMed ID: 38008032
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
    Chen W; Wang F; Yu X; Qi J; Dong H; Cui B; Zhang Q; Wu Y; An J; Ni N; Liu C; Han Y; Zhang S; Schmitt CA; Deng J; Yu Y; Du J
    Oncogene; 2024 May; 43(18):1328-1340. PubMed ID: 37950038
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Deciphering Brain Metastasis Stem Cell Properties From Colorectal cancer Highlights Specific Stemness Signature and Shared Molecular Features.
    Desette A; Guichet PO; Emambux S; Masliantsev K; Cortes U; Ndiaye B; Milin S; George S; Faigner M; Tisserand J; Gaillard A; Brot S; Wager M; Tougeron D; Karayan-Tapon L
    Cell Mol Gastroenterol Hepatol; 2023; 16(5):757-782. PubMed ID: 37482243
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Genomic characteristics and prognosis of lung cancer patients with MSI-H: A cohort study.
    Tian J; Wang H; Lu C; Liu L; Zhang X; Xie Y; Li R; Lv X; Fu D; Zhang L; Fang X; Wang X; Hu J; Liu X; Huang X; Zhao Q; Luo N; Tang H; Zhong Z; He Y; Li L
    Lung Cancer; 2023 Jul; 181():107255. PubMed ID: 37244039
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Frequently mutated genes in predicting the relapse of stage I lung adenocarcinoma.
    Rao W; Yang L; Dai N; Zhang L; Liu J; Yang B; Li M; Shan J; Wang Q; Wang D
    Clin Transl Oncol; 2023 Jun; 25(6):1767-1778. PubMed ID: 36739576
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genomic analyses of high-grade neuroendocrine gynecological malignancies reveal a unique mutational landscape and therapeutic vulnerabilities.
    Mahdi H; Joehlin-Price A; Elishaev E; Dowlati A; Abbas A
    Mol Oncol; 2021 Dec; 15(12):3545-3558. PubMed ID: 34245124
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Transformation of advanced lung adenocarcinoma to acquired T790M resistance mutation adenosquamous carcinoma following tyrosine kinase inhibitor: a case report.
    Liu Q; Wu L; Zhang S
    Tumori; 2021 Dec; 107(6):NP5-NP10. PubMed ID: 33896242
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Recruitment of kmt2c/mll3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in cancer.
    Chang A; Liu L; Ashby JM; Wu D; Chen Y; O'Neill SS; Huang S; Wang J; Wang G; Cheng D; Tan X; Petty WJ; Pasche BC; Xiang R; Zhang W; Sun P
    Cancer Res; 2021 Jun; 81(12):3358-3373. PubMed ID: 33853832
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Integration of comprehensive genomic profiling, tumor mutational burden, and PD-L1 expression to identify novel biomarkers of immunotherapy in non-small cell lung cancer.
    Shi Y; Lei Y; Liu L; Zhang S; Wang W; Zhao J; Zhao S; Dong X; Yao M; Wang K; Zhou Q
    Cancer Med; 2021 Apr; 10(7):2216-2231. PubMed ID: 33655698
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Targeted next-generation sequencing for cancer-associated gene mutation and copy number detection in 206 patients with non-small-cell lung cancer.
    Zheng S; Wang X; Fu Y; Li B; Xu J; Wang H; Huang Z; Xu H; Qiu Y; Shi Y; Li K
    Bioengineered; 2021 Dec; 12(1):791-802. PubMed ID: 33629637
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Mutation profile of non-small cell lung cancer revealed by next generation sequencing.
    Chang YS; Tu SJ; Chen YC; Liu TY; Lee YT; Yen JC; Fang HY; Chang JG
    Respir Res; 2021 Jan; 22(1):3. PubMed ID: 33407425
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. [Analysis of the feasibility and prognostic value of circulating tumor DNA in detecting gene mutations in small cell lung cancer].
    Jin Y; Chen YM; Hu X; Tang HR; Yu XM; Fan Y; Xu YJ; Xu HM; Li PS; Li Q; Chang LP; Guan YF; Chen M
    Zhonghua Yi Xue Za Zhi; 2020 Dec; 100(45):3614-3621. PubMed ID: 33333686
    [No Abstract]    [Full Text] [Related]  

  • 15. Comprehensive genomic profile of Chinese lung cancer patients and mutation characteristics of individuals resistant to icotinib/gefitinib.
    Shang Y; Li X; Liu W; Shi X; Yuan S; Huo R; Fang G; Han X; Zhang J; Wang K; Dou Z; Zhang Y; Zang A; Zhang L
    Sci Rep; 2020 Nov; 10(1):20243. PubMed ID: 33219256
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Association of clinico-genomic characteristics with tumor mutational burden in small cell lung cancer patients.
    Kachroo S; Shao C; Desai K; He J; Jin F; Sen S
    Future Oncol; 2021 Feb; 17(4):423-433. PubMed ID: 33198513
    [No Abstract]    [Full Text] [Related]  

  • 17. kmt2c promoter methylation in plasma-circulating tumor DNA is a prognostic biomarker in non-small cell lung cancer.
    Mastoraki S; Balgkouranidou I; Tsaroucha E; Klinakis A; Georgoulias V; Lianidou E
    Mol Oncol; 2021 Sep; 15(9):2412-2422. PubMed ID: 33159839
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. H3K4 Methylation Status and Lysine Specific Methyltransferase kmt2c Expression Correlate with Prognosis in lung Adenocarcinoma.
    Bosgana P; Nikou S; Dimitrakopoulos FI; Logotheti S; Tzelepi V; Kalophonos C; Bravou V; Kourea E; Sampsonas F; Zolota V
    Curr Mol Pharmacol; 2021; 14(6):1028-1036. PubMed ID: 32867667
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Development and validation of a genomic mutation signature to predict response to PD-1 inhibitors in non-squamous NSCLC: a multicohort study.
    Bai X; Wu DH; Ma SC; Wang J; Tang XR; Kang S; Fu QJ; Cao CH; Luo HS; Chen YH; Zhu HB; Yan HH; Wu YL; Dong ZY
    J Immunother Cancer; 2020 Jun; 8(1):. PubMed ID: 32606052
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Procarcinogen Activation and Mutational Signatures Model the Initiation of Carcinogenesis in Human Urothelial Tissues In Vitro.
    Baker SC; Mason AS; Southgate J
    Eur Urol; 2020 Aug; 78(2):143-147. PubMed ID: 32349929
    [TBL] [Abstract] [Full Text] [Related]  


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