Terms: = Lung cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
150 results:
1. Genomic Landscape of Pulmonary Sarcomatoid Carcinoma.
Kwon HJ; Lee S; Han YB; Lee J; Kwon S; Kim H; Chung JH
Cancer Res Treat; 2024 Apr; 56(2):442-454. PubMed ID: 37973906
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2. Tetrahydrobiopterin from cyanide-degrading bacterium Bacillus pumilus strain SVD06 induces apoptosis in human lung adenocarcinoma cell (A549).
Mahendran R; Selvaraj SP; Dhanapal AR; Sarasa SB; Mathias BM; Thankappan B; Femil Selta DR; Naveen P; Poorani R; Sundhar N; Pillai MM; Selvakumar R; Huang CY; Eswaran R; Angayarkanni J
Biotechnol Appl Biochem; 2023 Dec; 70(6):2052-2068. PubMed ID: 37731306
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3. Combination Therapy With mdm2 and MEK Inhibitors Is Effective in Patient-Derived Models of lung Adenocarcinoma With Concurrent Oncogenic Drivers and mdm2 Amplification.
Elkrief A; Odintsov I; Markov V; Caeser R; Sobczuk P; Tischfield SE; Bhanot U; Vanderbilt CM; Cheng EH; Drilon A; Riely GJ; Lockwood WW; de Stanchina E; Tirunagaru VG; Doebele RC; Quintanal-Villalonga Á; Rudin CM; Somwar R; Ladanyi M
J Thorac Oncol; 2023 Sep; 18(9):1165-1183. PubMed ID: 37182602
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4. Targeting neddylation as a novel approach to lung cancer treatment (Review).
Tian Z; Li J; Ma R; Li T; Sun Z; Huang S
Int J Oncol; 2023 May; 62(5):. PubMed ID: 37083098
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5. Mutational Damages in Malignant lung Tumors.
Yermekova S; Orazgaliyeva M; Goncharova T; Rakhimbekova F; Dushimova Z; Vasilieva T
Asian Pac J Cancer Prev; 2023 Feb; 24(2):709-716. PubMed ID: 36853323
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6. Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models.
Tucker ER; Jiménez I; Chen L; Bellini A; Gorrini C; Calton E; Gao Q; Che H; Poon E; Jamin Y; Martins Da Costa B; Barker K; Shrestha S; Hutchinson JC; Dhariwal S; Goodman A; Del Nery E; Gestraud P; Bhalshankar J; Iddir Y; Saberi-Ansari E; Saint-Charles A; Geoerger B; Marques Da Costa ME; Pierre-Eugène C; Janoueix-Lerosey I; Decaudin D; Nemati F; Carcaboso AM; Surdez D; Delattre O; George SL; Chesler L; Tweddle DA; Schleiermacher G
Clin Cancer Res; 2023 Apr; 29(7):1317-1331. PubMed ID: 36602782
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7. Design, synthesis, and biological evaluation of novel protopanoxadiol derivatives based PROTACs technology for the treatment of lung cancer.
Wang P; Zhu H; Liu J; Xie S; Xu S; Chen Y; Xu J; Zhao Y; Zhu Z; Xu J
Bioorg Chem; 2023 Feb; 131():106327. PubMed ID: 36549254
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8. Atezolizumab Plus Bevacizumab as First-line treatment for Patients With Metastatic Nonsquamous Non-Small Cell lung cancer With High Tumor Mutation Burden: A Nonrandomized Controlled Trial.
Provencio M; Ortega AL; Coves-Sarto J; Calvo V; Marsé-Fabregat R; Dómine M; Guirado M; Carcereny E; Fernández N; Álvarez R; Blanco R; León-Mateos L; Sánchez-Torres JM; Sullivan IG; Cobo M; Sánchez-Hernández A; Massuti B; Sierra-Rodero B; Mártinez-Toledo C; Serna-Blasco R; Romero A; Cruz-Bermúdez A
JAMA Oncol; 2023 Mar; 9(3):344-353. PubMed ID: 36520426
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9. Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis.
Wei RQ; Zhang WM; Liang Z; Piao C; Zhu G
Can Respir J; 2022; 2022():1394088. PubMed ID: 36072642
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10. p53 as a unique target of action of cisplatin in acute leukaemia cells.
Kumar S; Tchounwou PB
J Cell Mol Med; 2022 Sep; 26(17):4727-4739. PubMed ID: 35946055
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11. MIR4435-2HG Is a Potential Pan-cancer Biomarker for Diagnosis and Prognosis.
Zhong C; Xie Z; Zeng LH; Yuan C; Duan S
Front Immunol; 2022; 13():855078. PubMed ID: 35784328
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12. IDO1 plays a tumor-promoting role via mdm2-mediated suppression of the p53 pathway in diffuse large B-cell lymphoma.
Sun C; Li M; Zhang L; Sun F; Chen H; Xu Y; Lan Y; Zhang L; Lu S; Zhu J; Huang J; Wang J; Hu Y; Feng Y; Zhang Y
Cell Death Dis; 2022 Jun; 13(6):572. PubMed ID: 35760783
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13. Genomic landscape of non-small-cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency.
Ashok Kumar P; Graziano SL; Danziger N; Pavlick D; Severson EA; Ramkissoon SH; Huang RSP; Decker B; Ross JS
Cancer Med; 2023 Jan; 12(2):1157-1166. PubMed ID: 35747993
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14. Genome-wide CRISPR/Cas9 screening for therapeutic targets in NSCLC carrying wild-type TP53 and receptor tyrosine kinase genes.
Wang Q; Li J; Zhu J; Mao J; Duan C; Liang X; Zhu L; Zhu M; Zhang Z; Lin F; Guo R
Clin Transl Med; 2022 Jun; 12(6):e882. PubMed ID: 35692096
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15. 2-Methoxy-5((3,4,5-trimethosyphenyl) seleninyl) phenol causes G2/M cell cycle arrest and apoptosis in NSCLC cells through mitochondrial apoptotic pathway and mdm2 inhibition.
Liu Y; Meng Y; Bian J; Liu B; Li X; Guan Q; Li Z; Zhang W; Wu Y; Zuo D
J Biochem Mol Toxicol; 2022 Jul; 36(7):e23066. PubMed ID: 35384151
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16. Zebrafish patient-derived xenograft models predict lymph node involvement and treatment outcome in non-small cell lung cancer.
Ali Z; Vildevall M; Rodriguez GV; Tandiono D; Vamvakaris I; Evangelou G; Lolas G; Syrigos KN; Villanueva A; Wick M; Omar S; Erkstam A; Schueler J; Fahlgren A; Jensen LD
J Exp Clin Cancer Res; 2022 Feb; 41(1):58. PubMed ID: 35139880
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17. PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell lung cancer.
Yun M; Yingzi L; Jie G; Guanxin L; Zimei Z; Zhen C; Zhi L; Yingjie N; Lunquan S; Tao C; Yuezhen D; Chengzhi Z
Int J Biol Sci; 2022; 18(1):214-228. PubMed ID: 34975328
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18. Prediction of Genes Involved in lung cancer with a Systems Biology Approach Based on Comprehensive Gene Information.
Parvin S; Sedighian H; Sohrabi E; Mahboobi M; Rezaei M; Ghasemi D; Rezaei E
Biochem Genet; 2022 Aug; 60(4):1253-1273. PubMed ID: 34855070
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19. USP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer.
Huang YT; Cheng AC; Tang HC; Huang GC; Cai L; Lin TH; Wu KJ; Tseng PH; Wang GG; Chen WY
Cell Death Dis; 2021 Sep; 12(10):880. PubMed ID: 34580281
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20. High-Throughput Screen of Natural Compounds and Biomarkers for NSCLC treatment by Differential Expression and Weighted Gene Coexpression Network Analysis (WGCNA).
Kui L; Li M; Yang X; Yang L; Kong Q; Pan Y; Xu Z; Wang S; Mo D; Dong Y; Liu Y; Miao J
Biomed Res Int; 2021; 2021():5955343. PubMed ID: 34485520
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