BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND MYC, c-Myc, 4609, ENSG00000136997 AND Treatment
551 results:

  • 1. The TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability.
    Abad E; Sandoz J; Romero G; Zadra I; Urgel-Solas J; Borredat P; Kourtis S; Ortet L; Martínez CM; Weghorn D; Sdelci S; Janic A
    J Exp Clin Cancer Res; 2024 Apr; 43(1):127. PubMed ID: 38685100
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Transitioning to a Personalized Approach in Molecularly Subtyped Small-Cell lung cancer (SCLC).
    Grenda A; Krawczyk P; Obara A; Gajek Ł; Łomża-Łaba A; Milanowski J
    Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673793
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. NDRG2 acts as a negative regulator of the progression of small-cell lung cancer through the modulation of the PTEN-AKT-mTOR signalling cascade.
    Ma Z; Ma Y; Feng J; Xu Z; Cheng C; Qin J; Li S; Jiang J; Kong R
    Toxicol Appl Pharmacol; 2024 Apr; 485():116915. PubMed ID: 38537875
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer.
    Zhang YZ; Lai HL; Huang C; Jiang ZB; Yan HX; Wang XR; Xie C; Huang JM; Ren WK; Li JX; Zhai ZR; Yao XJ; Wu QB; Leung EL
    Phytomedicine; 2024 Jun; 128():155431. PubMed ID: 38537440
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Polyphyllin I enhances tumor necrosis factor-related apoptosis-inducing ligand-induced inhibition of human osteosarcoma cell growth downregulating the Wnt/β-catenin pathway.
    Junli C; Fulai Z; Xingyuan S; Xiaoping MA; Peng Z; Chujie Z; Binhao S; Wenchao GU; Yongjun W; Yanping Y
    J Tradit Chin Med; 2024 Apr; 44(2):251-259. PubMed ID: 38504531
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Evolutionary trajectories of small cell lung cancer under therapy.
    George J; Maas L; Abedpour N; Cartolano M; Kaiser L; Fischer RN; Scheel AH; Weber JP; Hellmich M; Bosco G; Volz C; Mueller C; Dahmen I; John F; Alves CP; Werr L; Panse JP; Kirschner M; Engel-Riedel W; Jürgens J; Stoelben E; Brockmann M; Grau S; Sebastian M; Stratmann JA; Kern J; Hummel HD; Hegedüs B; Schuler M; Plönes T; Aigner C; Elter T; Toepelt K; Ko YD; Kurz S; Grohé C; Serke M; Höpker K; Hagmeyer L; Doerr F; Hekmath K; Strapatsas J; Kambartel KO; Chakupurakal G; Busch A; Bauernfeind FG; Griesinger F; Luers A; Dirks W; Wiewrodt R; Luecke A; Rodermann E; Diel A; Hagen V; Severin K; Ullrich RT; Reinhardt HC; Quaas A; Bogus M; Courts C; Nürnberg P; Becker K; Achter V; Büttner R; Wolf J; Peifer M; Thomas RK
    Nature; 2024 Mar; 627(8005):880-889. PubMed ID: 38480884
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Acquired Cross-Resistance in Small Cell lung cancer due to Extrachromosomal DNA Amplification of myc Paralogs.
    Pal Choudhuri S; Girard L; Lim JYS; Wise JF; Freitas B; Yang D; Wong E; Hamilton S; Chien VD; Kim YJ; Gilbreath C; Zhong J; Phat S; Myers DT; Christensen CL; Mazloom-Farsibaf H; Stanzione M; Wong KK; Hung YP; Farago AF; Meador CB; Dyson NJ; Lawrence MS; Wu S; Drapkin BJ
    Cancer Discov; 2024 May; 14(5):804-827. PubMed ID: 38386926
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. C-myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer.
    Lang C; Megyesfalvi Z; Lantos A; Oberndorfer F; Hoda MA; Solta A; Ferencz B; Fillinger J; Solyom-Tisza A; Querner AS; Egger F; Boettiger K; Klikovits T; Timelthaler G; Renyi-Vamos F; Aigner C; Hoetzenecker K; Laszlo V; Schelch K; Dome B
    World J Surg Oncol; 2024 Feb; 22(1):57. PubMed ID: 38369463
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Influence of
    Naqash AR; Floudas CS; Aber E; Maoz A; Nassar AH; Adib E; Choucair K; Xiu J; Baca Y; Ricciuti B; Alessi JV; Awad MM; Kim C; Judd J; Raez LE; Lopes G; Nieva JJ; Borghaei H; Takebe N; Ma PC; Halmos B; Kwiatkowski DJ; Liu SV; Mamdani H
    JCO Precis Oncol; 2024 Feb; 8():e2300371. PubMed ID: 38330261
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Lineage-specific intolerance to oncogenic drivers restricts histological transformation.
    Gardner EE; Earlie EM; Li K; Thomas J; Hubisz MJ; Stein BD; Zhang C; Cantley LC; Laughney AM; Varmus H
    Science; 2024 Feb; 383(6683):eadj1415. PubMed ID: 38330136
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas.
    Liu S; Chai T; Garcia-Marques F; Yin Q; Hsu EC; Shen M; Shaw Toland AM; Bermudez A; Hartono AB; Massey CF; Lee CS; Zheng L; Baron M; Denning CJ; Aslan M; Nguyen HM; Nolley R; Zoubeidi A; Das M; Kunder CA; Howitt BE; Soh HT; Weissman IL; Liss MA; Chin AI; Brooks JD; Corey E; Pitteri SJ; Huang J; Stoyanova T
    Cell Rep Med; 2024 Feb; 5(2):101381. PubMed ID: 38244540
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Transformation to small cell lung cancer is irrespective of EGFR and accelerated by SMAD4-mediated ASCL1 transcription independently of RB1 in non-small cell lung cancer.
    Ding X; Shi MX; Liu D; Cao JX; Zhang KX; Zhang RD; Zhang LP; Ai KX; Su B; Zhang J
    Cell Commun Signal; 2024 Jan; 22(1):45. PubMed ID: 38233864
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The radiation- and chemo-sensitizing capacity of diclofenac can be predicted by a decreased lactate metabolism and stress response.
    Schwab M; Dezfouli AB; Khosravi M; Alkotub B; Bauer L; Birgani MJT; Multhoff G
    Radiat Oncol; 2024 Jan; 19(1):7. PubMed ID: 38229111
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. LINC00629, a HOXB4-downregulated long noncoding RNA, inhibits glycolysis and ovarian cancer progression by destabilizing c-myc.
    Liu J; Zhu Y; Wang H; Han C; Wang Y; Tang R
    Cancer Sci; 2024 Mar; 115(3):804-819. PubMed ID: 38182548
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. ZAP-70 augments tonic B-cell receptor and CCR7 signaling in IGHV-unmutated chronic lymphocytic leukemia.
    Chen J; Sathiaseelan V; Reddy Chilamakuri CS; Roamio Franklin VN; Jakwerth CA; D'Santos C; Ringshausen I
    Blood Adv; 2024 Mar; 8(5):1167-1178. PubMed ID: 38113463
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity.
    Kwon J; Zhang J; Mok B; Allsup S; Kim C; Toretsky J; Han C
    Mol Cancer; 2023 Dec; 22(1):204. PubMed ID: 38093367
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Inhibition of demethylase by IOX1 modulates chromatin accessibility to enhance NSCLC radiation sensitivity through attenuated PIF1.
    Li Q; Qin K; Tian Y; Chen B; Zhao G; Xu S; Wu L
    Cell Death Dis; 2023 Dec; 14(12):817. PubMed ID: 38086789
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Metformin Suppresses Stemness of Non-Small-Cell lung cancer Induced by Paclitaxel through FOXO3a.
    Tang Z; Zhang Y; Yu Z; Luo Z
    Int J Mol Sci; 2023 Nov; 24(23):. PubMed ID: 38068934
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation.
    Yu S; Zhang Y; Yang J; Xu H; Lan S; Zhao B; Luo M; Ma X; Zhang H; Wang S; Shen H; Zhang Y; Xu Y; Li R
    Eur J Med Chem; 2024 Jan; 263():115924. PubMed ID: 37992518
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells.
    Zhang K; Sun T; Li W; Guo Y; Li A; Hsieh M; Wang J; Wu J; Arvanitis L; Raz DJ
    Cell Commun Signal; 2023 Nov; 21(1):319. PubMed ID: 37946202
    [TBL] [Abstract] [Full Text] [Related]  


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