Terms: = Lung cancer AND MYCN, N-myc, 4613, ENSG00000134323, NMYC, MODED, ODED AND Treatment
59 results:
1. NDRG2 acts as a negative regulator of the progression of small-cell lung cancer through the modulation of the PTEN-AKT-mTOR signalling cascade.
Ma Z; Ma Y; Feng J; Xu Z; Cheng C; Qin J; Li S; Jiang J; Kong R
Toxicol Appl Pharmacol; 2024 Apr; 485():116915. PubMed ID: 38537875
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2. C-Myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer.
Lang C; Megyesfalvi Z; Lantos A; Oberndorfer F; Hoda MA; Solta A; Ferencz B; Fillinger J; Solyom-Tisza A; Querner AS; Egger F; Boettiger K; Klikovits T; Timelthaler G; Renyi-Vamos F; Aigner C; Hoetzenecker K; Laszlo V; Schelch K; Dome B
World J Surg Oncol; 2024 Feb; 22(1):57. PubMed ID: 38369463
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3. A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors.
Bauer TM; Moore KN; Rader JS; Simpkins F; Mita AC; Beck JT; Hart L; Chu Q; Oza A; Tinker AV; Imedio ER; Kumar S; Mugundu G; Jenkins S; Chmielecki J; Jones S; Spigel D; Fu S
Target Oncol; 2023 Jul; 18(4):517-530. PubMed ID: 37278879
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4. Mistletoe lectin inhibits growth of Myc-amplified small-cell lung cancer.
Shatat MA; Gauthier B; Yoon S; Yuan E; Yang P; Narla G; Dowlati A; Lee RT
Cancer Med; 2023 Apr; 12(7):8378-8387. PubMed ID: 36562288
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5. An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies.
Orlando E; Medo M; Bensimon A; Quintin A; Riedo R; Roth SM; Riether C; Marti TM; Aebersold DM; Medová M; Aebersold R; Zimmer Y
Cell Mol Life Sci; 2022 Dec; 80(1):6. PubMed ID: 36494469
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6. YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma.
Yu W; Zhang C; Wang Y; Tian X; Miao Y; Meng F; Ma L; Zhang X; Xia J
Cancer Gene Ther; 2023 Jan; 30(1):149-162. PubMed ID: 36123390
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7. Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors
Khazan N; Kim KK; Hansen JN; Singh NA; Moore T; Snyder CWA; Pandita R; Strawderman M; Fujihara M; Takamura Y; Jian Y; Battaglia N; Yano N; Teramoto Y; Arnold LA; Hopson R; Kishor K; Nayak S; Ojha D; Sharon A; Ashton JM; Wang J; Milano MT; Miyamoto H; Linehan DC; Gerber SA; Kawar N; Singh AP; Tabdanov ED; Dokholyan NV; Kakuta H; Jurutka PW; Schor NF; Rowswell-Turner RB; Singh RK; Moore RG
J Med Chem; 2022 Apr; 65(8):6039-6055. PubMed ID: 35404047
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8. Real-world circulating tumor DNA analysis depicts resistance mechanism and clonal evolution in ALK inhibitor-treated lung adenocarcinoma patients.
Hua G; Zhang X; Zhang M; Wang Q; Chen X; Yu R; Bao H; Liu J; Wu X; Shao Y; Liang B; Lu K
ESMO Open; 2022 Feb; 7(1):100337. PubMed ID: 35123209
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9. Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins.
Chi YH; Yeh TK; Ke YY; Lin WH; Tsai CH; Wang WP; Chen YT; Su YC; Wang PC; Chen YF; Wu ZW; Yeh JY; Hung MC; Wu MH; Wang JY; Chen CP; Song JS; Shih C; Chen CT; Chang CP
J Med Chem; 2021 Jun; 64(11):7312-7330. PubMed ID: 34009981
[TBL] [Abstract] [Full Text] [Related]
10. Novel Primary Human cancer Stem-Like Cell Populations from Non-Small Cell lung cancer: Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling.
Windmöller BA; Beshay M; Helweg LP; Flottmann C; Beermann M; Förster C; Wilkens L; Greiner JFW; Kaltschmidt C; Kaltschmidt B
Cells; 2021 Apr; 10(5):. PubMed ID: 33925297
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11. Genomic Profiling and Clinicopathological Characteristics of Neuroendocrine Tumors of the lung in East Asian Patients.
Kim M; Chung YS; Kim KA; Shim HS
In Vivo; 2020; 34(6):3375-3385. PubMed ID: 33144445
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12.
Grunblatt E; Wu N; Zhang H; Liu X; Norton JP; Ohol Y; Leger P; Hiatt JB; Eastwood EC; Thomas R; Ibrahim AH; Jia D; Basom R; Eaton KD; Martins R; Houghton AM; MacPherson D
Genes Dev; 2020 Sep; 34(17-18):1210-1226. PubMed ID: 32820040
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13. Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity
Ohol YM; Sun MT; Cutler G; Leger PR; Hu DX; Biannic B; Rana P; Cho C; Jacobson S; Wong ST; Sanchez J; Shah N; Pookot D; Abraham B; Young K; Suthram S; Marshall LA; Bradford D; Kozon N; Han X; Okano A; Maung J; Colas C; Schwarz J; Wustrow D; Brockstedt DG; Kassner PD
Mol Cancer Ther; 2020 Oct; 19(10):1970-1980. PubMed ID: 32788207
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14. Steroid receptor-associated and regulated protein is a biomarker in predicting the clinical outcome and treatment response in malignancies.
Naderi A
Cancer Rep (Hoboken); 2020 Oct; 3(5):e1267. PubMed ID: 32706923
[TBL] [Abstract] [Full Text] [Related]
15. MYC, MYCL, and mycn as therapeutic targets in lung cancer.
Massó-Vallés D; Beaulieu ME; Soucek L
Expert Opin Ther Targets; 2020 Feb; 24(2):101-114. PubMed ID: 32003251
[No Abstract] [Full Text] [Related]
16. The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of mycn status.
Trigg RM; Lee LC; Prokoph N; Jahangiri L; Reynolds CP; Amos Burke GA; Probst NA; Han M; Matthews JD; Lim HK; Manners E; Martinez S; Pastor J; Blanco-Aparicio C; Merkel O; de Los Fayos Alonso IG; Kodajova P; Tangermann S; Högler S; Luo J; Kenner L; Turner SD
Nat Commun; 2019 Nov; 10(1):5428. PubMed ID: 31780656
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17. Morin Protects Human Respiratory Cells from PM
Veerappan I; Sankareswaran SK; Palanisamy R
Int J Environ Res Public Health; 2019 Jul; 16(13):. PubMed ID: 31284452
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18. Nobiletin Enhances Chemosensitivity to Adriamycin through Modulation of the Akt/GSK3β/β⁻Catenin/mycn/MRP1 Signaling Pathway in A549 Human Non-Small-Cell lung cancer Cells.
Moon JY; Manh Hung LV; Unno T; Cho SK
Nutrients; 2018 Nov; 10(12):. PubMed ID: 30486290
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19. Targeting of SGK1 by miR-576-3p Inhibits lung Adenocarcinoma Migration and Invasion.
Greenawalt EJ; Edmonds MD; Jain N; Adams CM; Mitra R; Eischen CM
Mol Cancer Res; 2019 Jan; 17(1):289-298. PubMed ID: 30257988
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20. Identification of high-risk human papillomavirus and Rb/E2F pathway genomic alterations in mutually exclusive subsets of colorectal neuroendocrine carcinoma.
Shamir ER; Devine WP; Pekmezci M; Umetsu SE; Krings G; Federman S; Cho SJ; Saunders TA; Jen KY; Bergsland E; Jones K; Kim GE; Kakar S; Chiu CY; Joseph NM
Mod Pathol; 2019 Feb; 32(2):290-305. PubMed ID: 30237525
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