BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND PALB2, ENSG00000083093, 79728
21 results:

  • 1. Poor response to sintilimab plus chemotherapy in a pulmonary epithelioid hemangioendothelioma patient: a case report.
    Zeng H; Tang X; Tian X; Liu Y; Tian P
    Immunotherapy; 2023 Feb; 15(2):77-83. PubMed ID: 36695105
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Tumor Fraction Correlates With Detection of Actionable Variants Across > 23,000 Circulating Tumor DNA Samples.
    Husain H; Pavlick DC; Fendler BJ; Madison RW; Decker B; Gjoerup O; Parachoniak CA; McLaughlin-Drubin M; Erlich RL; Schrock AB; Frampton GM; Das Thakur M; Oxnard GR; Tukachinsky H
    JCO Precis Oncol; 2022 Oct; 6():e2200261. PubMed ID: 36265119
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Contribution of germline palb2 variants to an unselected and prospectively registered pancreatic cancer patient cohort in Pakistan.
    Muhammad N; Sadaqat R; Naeemi H; Masood I; Hassan U; Ijaz B; Hanif F; Syed AA; Yusuf MA; Rashid MU
    HPB (Oxford); 2022 Dec; 24(12):2134-2144. PubMed ID: 36175305
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort.
    Leibowitz BD; Dougherty BV; Bell JSK; Kapilivsky J; Michuda J; Sedgewick AJ; Munson WA; Chandra TA; Dry JR; Beaubier N; Igartua C; Taxter T
    BMC Cancer; 2022 May; 22(1):587. PubMed ID: 35643464
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and palb2 in a Tumor-Only Genomic Testing Program.
    Bychkovsky BL; Li T; Sotelo J; Tayob N; Mercado J; Gomy I; Chittenden A; Kane S; Stokes S; Hughes ME; Kim JS; Umeton R; Awad MM; Konstantinopoulos PA; Yurgelun MB; Wolpin BM; Taplin ME; Newmark RE; Johnson BE; Lindeman NI; MacConaill LE; Garber JE; Lin NU
    Clin Cancer Res; 2022 Jun; 28(11):2349-2360. PubMed ID: 35363308
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial.
    de Bono JS; Mehra N; Scagliotti GV; Castro E; Dorff T; Stirling A; Stenzl A; Fleming MT; Higano CS; Saad F; Buttigliero C; van Oort IM; Laird AD; Mata M; Chen HC; Healy CG; Czibere A; Fizazi K
    Lancet Oncol; 2021 Sep; 22(9):1250-1264. PubMed ID: 34388386
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Basaloid Squamous Cell Carcinoma of the Uterine Cervix: Report of a Case With Molecular Analysis.
    Munkhdelger J; Shimooka T; Koyama Y; Ikeda S; Mikami Y; Fukuoka J; Hori T; Bychkov A
    Int J Surg Pathol; 2021 Oct; 29(7):770-774. PubMed ID: 33792431
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Phase 2 Study of Talazoparib in Patients With Homologous Recombination Repair-Deficient Squamous Cell lung cancer: lung-MAP Substudy S1400G.
    Owonikoko TK; Redman MW; Byers LA; Hirsch FR; Mack PC; Schwartz LH; Bradley JD; Stinchcombe TE; Leighl NB; Al Baghdadi T; Lara P; Miao J; Kelly K; Ramalingam SS; Herbst RS; Papadimitrakopoulou V; Gandara DR
    Clin Lung Cancer; 2021 May; 22(3):187-194.e1. PubMed ID: 33583720
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or palb2 mutation.
    Wattenberg MM; Asch D; Yu S; O'Dwyer PJ; Domchek SM; Nathanson KL; Rosen MA; Beatty GL; Siegelman ES; Reiss KA
    Br J Cancer; 2020 Feb; 122(3):333-339. PubMed ID: 31787751
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. USP22 Interacts with palb2 and Promotes Chemotherapy Resistance via Homologous Recombination of DNA Double-Strand Breaks.
    Nardi IK; Stark JM; Larsen A; Salgia R; Raz DJ
    Mol Cancer Res; 2020 Mar; 18(3):424-435. PubMed ID: 31685642
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Homologous recombination in lung cancer, germline and somatic mutations, clinical and phenotype characterization.
    Kadouri L; Rottenberg Y; Zick A; Hamburger T; Lipson D; Peretz T; Nechushtan H
    Lung Cancer; 2019 Nov; 137():48-51. PubMed ID: 31542568
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Epidemiology of Breast cancer in Women.
    Coughlin SS
    Adv Exp Med Biol; 2019; 1152():9-29. PubMed ID: 31456177
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Identification of driver genes and somatic mutations in cell-free DNA of patients with pulmonary lymphangioleiomyomatosis.
    Zhang L; Wang MJ; Wang W; Zhao JY; Wu JL; Liu YP; Zhu H; Qu JM; Zhou M
    Int J Cancer; 2020 Jan; 146(1):103-114. PubMed ID: 31199508
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Association of palb2 Messenger RNA Expression with Platinum-Docetaxel Efficacy in Advanced Non-Small Cell lung cancer.
    Karachaliou N; Bracht JWP; Fernandez Bruno M; Drozdowskyj A; Gimenez Capitan A; Moran T; Carcereny E; Cobo M; Domine M; Chaib I; Ramirez JL; Camps C; Provencio M; Vergnenegre A; Lopez-Vivanco G; Majem M; Massuti B; Rosell R
    J Thorac Oncol; 2019 Feb; 14(2):304-310. PubMed ID: 30472259
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Sputum Detection of Predisposing Genetic Mutations in Women with Pulmonary Nontuberculous Mycobacterial Disease.
    Philley JV; Hertweck KL; Kannan A; Brown-Elliott BA; Wallace RJ; Kurdowska A; Ndetan H; Singh KP; Miller EJ; Griffith DE; Dasgupta S
    Sci Rep; 2018 Jul; 8(1):11336. PubMed ID: 30054559
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Germline mutations in DNA repair genes predispose asbestos-exposed patients to malignant pleural mesothelioma.
    Betti M; Casalone E; Ferrante D; Aspesi A; Morleo G; Biasi A; Sculco M; Mancuso G; Guarrera S; Righi L; Grosso F; Libener R; Pavesi M; Mariani N; Casadio C; Boldorini R; Mirabelli D; Pasini B; Magnani C; Matullo G; Dianzani I
    Cancer Lett; 2017 Oct; 405():38-45. PubMed ID: 28687356
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Frequency of germline palb2 mutations among women with epithelial ovarian cancer.
    Kotsopoulos J; Sopik V; Rosen B; Fan I; McLaughlin JR; Risch H; Sun P; Narod SA; Akbari MR
    Fam Cancer; 2017 Jan; 16(1):29-34. PubMed ID: 27631815
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Inherited Mutations in Women With Ovarian Carcinoma.
    Norquist BM; Harrell MI; Brady MF; Walsh T; Lee MK; Gulsuner S; Bernards SS; Casadei S; Yi Q; Burger RA; Chan JK; Davidson SA; Mannel RS; DiSilvestro PA; Lankes HA; Ramirez NC; King MC; Swisher EM; Birrer MJ
    JAMA Oncol; 2016 Apr; 2(4):482-90. PubMed ID: 26720728
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Primary human non-small cell lung and pancreatic tumorgraft models--utility and applications in drug discovery and tumor biology.
    Calles A; Rubio-Viqueira B; Hidalgo M
    Curr Protoc Pharmacol; 2013 Jun; Chapter 14():Unit 14.26. PubMed ID: 23744711
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.
    Hast BE; Goldfarb D; Mulvaney KM; Hast MA; Siesser PF; Yan F; Hayes DN; Major MB
    Cancer Res; 2013 Apr; 73(7):2199-210. PubMed ID: 23382044
    [TBL] [Abstract] [Full Text] [Related]  


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