BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
29 results:

  • 1. BPTF Drives Gastric cancer Resistance to EGFR Inhibitor by Epigenetically Regulating the C-MYC/plcg1/Perk Axis.
    Li F; Yu J; Pan T; Feng H; Li J; Yu B; Fan Z; Sang Q; Chen M; Zang M; Hou J; Wu X; Yu Y; Li YY; Yan C; Zhu Z; Su L; Liu B
    Adv Sci (Weinh); 2023 Dec; 10(34):e2303091. PubMed ID: 37863665
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Adenoid cystic carcinoma of Bartholin's gland, a case report with genomic data and literature review.
    Evin C; Just PA; Borghese B; Fabiano E; Bennani S; Canny E; Marisa L; Derive N; Laurent-Puig P; Alexandre J; Durdux C
    Cancer Radiother; 2023 Jun; 27(4):328-336. PubMed ID: 36759241
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis.
    Xu J; Zhong Y; Yin H; Linneman J; Luo Y; Xia S; Xia Q; Yang L; Huang X; Kang K; Wang J; Niu Y; Li L; Gou D
    J Hypertens; 2022 Sep; 40(9):1795-1807. PubMed ID: 35848503
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. SNCA correlates with immune infiltration and serves as a prognostic biomarker in lung adenocarcinoma.
    Zhang X; Wu Z; Ma K
    BMC Cancer; 2022 Apr; 22(1):406. PubMed ID: 35421944
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A New Definition of Pyroptosis-Related Gene Markers to Predict the Prognosis of lung Adenocarcinoma.
    Zhang G; Yan Z
    Biomed Res Int; 2021; 2021():8175003. PubMed ID: 34869771
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis.
    Mandal S; Bandyopadhyay S; Tyagi K; Roy A
    Biochim Biophys Acta Rev Cancer; 2021 Dec; 1876(2):188619. PubMed ID: 34454048
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR.
    Ghosh S; Nataraj NB; Noronha A; Patkar S; Sekar A; Mukherjee S; Winograd-Katz S; Kramarski L; Verma A; Lindzen M; Garcia DD; Green J; Eisenberg G; Gil-Henn H; Basu A; Lender Y; Weiss S; Oren M; Lotem M; Geiger B; Ruppin E; Yarden Y
    Cell Rep; 2021 May; 35(8):109181. PubMed ID: 34038737
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia.
    Saliakoura M; Rossi Sebastiano M; Pozzato C; Heidel FH; Schnöder TM; Savic Prince S; Bubendorf L; Pinton P; A Schmid R; Baumgartner J; Freigang S; Berezowska SA; Rimessi A; Konstantinidou G
    Nat Cell Biol; 2020 Nov; 22(11):1382-1395. PubMed ID: 33077911
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. FGFR1 Is Critical for RBL2 Loss-Driven Tumor Development and Requires plcg1 Activation for Continued Growth of Small Cell lung cancer.
    Kim KB; Kim Y; Rivard CJ; Kim DW; Park KS
    Cancer Res; 2020 Nov; 80(22):5051-5062. PubMed ID: 32973083
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. PLCγ1‑dependent invasion and migration of cells expressing NSCLC‑associated EGFR mutants.
    Mittal S; Kamath A; Joseph AM; Rajala MS
    Int J Oncol; 2020 Oct; 57(4):989-1000. PubMed ID: 32945365
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells
    Lu X; Fu H; Chen R; Wang Y; Zhan Y; Song G; Hu T; Xia C; Tian X; Zhang B
    Int J Biol Sci; 2020; 16(8):1427-1440. PubMed ID: 32210730
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes.
    Lattanzio R; Iezzi M; Sala G; Tinari N; Falasca M; Alberti S; Buglioni S; Mottolese M; Perracchio L; Natali PG; Piantelli M
    BMC Cancer; 2019 Jul; 19(1):747. PubMed ID: 31362705
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer.
    Xie Z; Cheng D; Luo L; Shen G; Pan S; Pan Y; Chen B; Wang X; Liu Z; Zhang Y; Ye F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):905-919. PubMed ID: 29734851
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. [Inhibitory effect of imrecoxib combined with lobaplatin on tumor growth and lymph node metastasis of human lung cancer xenografts in nude mice].
    Wang DC; Wang LC; Wang LJ; Chen G; Zhao YX; Zhao ZF; Li YH
    Zhonghua Zhong Liu Za Zhi; 2016 May; 38(5):340-5. PubMed ID: 27188605
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Identification of gene markers in the development of smoking-induced lung cancer.
    Yang Z; Zhuan B; Yan Y; Jiang S; Wang T
    Gene; 2016 Jan; 576(1 Pt 3):451-7. PubMed ID: 26518718
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor.
    Hu Z; Hu Y; Liu X; Xi R; Zhang A; Liu D; Xie Q; Chen L
    Oncotarget; 2015 Oct; 6(31):31628-39. PubMed ID: 26375550
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Treatment with a Small Synthetic Compound, KMU-193, induces Apoptosis in A549 Human lung Carcinoma Cells through p53 Up-Regulation.
    Choi EY; Shin KC; Lee J; Kwon TK; Kim S; Park JW
    Asian Pac J Cancer Prev; 2015; 16(14):5883-7. PubMed ID: 26320467
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling.
    Cruse G; Beaven MA; Music SC; Bradding P; Gilfillan AM; Metcalfe DD
    Mol Biol Cell; 2015 May; 26(9):1711-27. PubMed ID: 25717186
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Identification of peptide regions of SERPINA1 and ENOSF1 and their protein expression as potential serum biomarkers for gastric cancer.
    Yang J; Xiong X; Wang X; Guo B; He K; Huang C
    Tumour Biol; 2015 Jul; 36(7):5109-18. PubMed ID: 25677901
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Prognosis of lung cancer patients with a past history of colorectal cancer.
    Hattori A; Suzuki K; Aokage K; Mimae T; Nagai K; Tsuboi M; Okada M
    Jpn J Clin Oncol; 2014 Nov; 44(11):1088-95. PubMed ID: 25156681
    [TBL] [Abstract] [Full Text] [Related]  


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