BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND RARA, RAR, 5914, ENSG00000131759, NR1B1 AND Treatment
46 results:

  • 1. ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and rar-dependent transcription.
    Gorodetska I; Offermann A; Püschel J; Lukiyanchuk V; Gaete D; Kurzyukova A; Freytag V; Haider MT; Fjeldbo CS; Di Gaetano S; Schwarz FM; Patil S; Borkowetz A; Erb HHH; Baniahmad A; Mircetic J; Lyng H; Löck S; Linge A; Lange T; Knopf F; Wielockx B; Krause M; Perner S; Dubrovska A
    Theranostics; 2024; 14(2):714-737. PubMed ID: 38169509
    [No Abstract]    [Full Text] [Related]  

  • 2. 5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling.
    Singh DK; Carcamo S; Farias EF; Hasson D; Zheng W; Sun D; Huang X; Cheung J; Nobre AR; Kale N; Sosa MS; Bernstein E; Aguirre-Ghiso JA
    Cell Rep; 2023 Jun; 42(6):112560. PubMed ID: 37267946
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeting the Retinoic Acid Pathway to Eradicate cancer Stem Cells.
    Brown G
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768694
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Combination treatment of Retinoic Acid Plus Focal Adhesion Kinase Inhibitor Prevents Tumor Growth and Breast cancer Cell Metastasis.
    Castro-Guijarro AC; Vanderhoeven F; Mondaca JM; Redondo AL; Zoppino FCM; Fernandez-Muñoz JM; Sanchez AM; Flamini MI
    Cells; 2022 Sep; 11(19):. PubMed ID: 36230951
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Targeting S100A9-ALDH1A1-Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant lung cancer.
    Biswas AK; Han S; Tai Y; Ma W; Coker C; Quinn SA; Shakri AR; Zhong TJ; Scholze H; Lagos GG; Mela A; Manova-Todorova K; de Stanchina E; Ferrando AA; Mendelsohn C; Canoll P; Yu HA; Paik PK; Saqi A; Shu CA; Kris MG; Massague J; Acharyya S
    Cancer Discov; 2022 Apr; 12(4):1002-1021. PubMed ID: 35078784
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Protein Kinase C Alpha (PKCα) overexpression leads to a better response to retinoid acid therapy through Retinoic Acid Receptor Beta (rarβ) activation in mammary cancer cells.
    Bessone MID; Berardi DE; Cirigliano SM; Delbart DI; Peters MG; Todaro LB; Urtreger AJ
    J Cancer Res Clin Oncol; 2020 Dec; 146(12):3241-3253. PubMed ID: 32865619
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Successful treatment of Therapy-related Acute Promyelocytic Leukemia with All-trans-retinoic acid Following Epirubicin for Hepatocellular Carcinoma and Docetaxel and Pembrolizumab Therapies for lung Carcinoma: A Triple Malignancy Case.
    Suzuki R; Kawai H; Furuya D; Akashi H; Ogawa Y; Kawada H; Ando K
    Tokai J Exp Clin Med; 2020 Jul; 45(2):92-96. PubMed ID: 32602108
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN.
    Wagner CE; Jurutka PW
    Methods Mol Biol; 2019; 2019():109-121. PubMed ID: 31359392
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN.
    Jurutka PW; Wagner CE
    Methods Mol Biol; 2019; 2019():95-108. PubMed ID: 31359391
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. S100A3 a partner protein regulating the stability/activity of rarα and PML-rarα in cellular models of breast/lung cancer and acute myeloid leukemia.
    Gianni M; Terao M; Kurosaki M; Paroni G; Brunelli L; Pastorelli R; Zanetti A; Lupi M; Acquavita A; Bolis M; Fratelli M; Rochette-Egly C; Garattini E
    Oncogene; 2019 Apr; 38(14):2482-2500. PubMed ID: 30532072
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Inhibition of cancer stem cell like cells by a synthetic retinoid.
    Chen J; Cao X; An Q; Zhang Y; Li K; Yao W; Shi F; Pan Y; Jia Q; Zhou W; Yang F; Wei F; Wang N; Yu B
    Nat Commun; 2018 Apr; 9(1):1406. PubMed ID: 29643385
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Enhanced expression of tumour suppressor rar-β by DSPC nano-formulated lipo-ATRA in the lung of B16F10 cell-implanted C57BL6 mice and in A549 cells.
    Berlin Grace VM; Reji RM; Sundaram V
    Life Sci; 2017 Sep; 184():10-17. PubMed ID: 28694088
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Curcumin Reactivates Silenced Tumor Suppressor Gene rarβ by Reducing DNA Methylation.
    Jiang A; Wang X; Shan X; Li Y; Wang P; Jiang P; Feng Q
    Phytother Res; 2015 Aug; 29(8):1237-45. PubMed ID: 25981383
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. CHFR methylation strongly correlates with methylation of DNA damage repair and apoptotic pathway genes in non-small cell lung cancer.
    Guo M; Alumkal J; Drachova T; Gao D; Marina SS; Jen J; Herman JG
    Discov Med; 2015 Mar; 19(104):151-8. PubMed ID: 25828518
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Synthetic phosphoethanolamine has in vitro and in vivo anti-leukemia effects.
    Ferreira AK; Santana-Lemos BA; Rego EM; Filho OM; Chierice GO; Maria DA
    Br J Cancer; 2013 Nov; 109(11):2819-28. PubMed ID: 24201752
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Reversal by rarα agonist Am580 of c-Myc-induced imbalance in rarα/rarγ expression during MMTV-Myc tumorigenesis.
    Bosch A; Bertran SP; Lu Y; Garcia A; Jones AM; Dawson MI; Farias EF
    Breast Cancer Res; 2012 Aug; 14(4):R121. PubMed ID: 22920668
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-rara.
    Rabellino A; Carter B; Konstantinidou G; Wu SY; Rimessi A; Byers LA; Heymach JV; Girard L; Chiang CM; Teruya-Feldstein J; Scaglioni PP
    Cancer Res; 2012 May; 72(9):2275-84. PubMed ID: 22406621
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1).
    Liu-Sullivan N; Zhang J; Bakleh A; Marchica J; Li J; Siolas D; Laquerre S; Degenhardt YY; Wooster R; Chang K; Hannon GF; Powers S
    Oncotarget; 2011 Dec; 2(12):1254-64. PubMed ID: 22248814
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Retinoic acid reduces chemotherapy-induced neuropathy in an animal model and patients with lung cancer.
    Arrieta Ó; Hernández-Pedro N; Fernández-González-Aragón MC; Saavedra-Pérez D; Campos-Parra AD; Ríos-Trejo MÁ; Cerón-Lizárraga T; Martínez-Barrera L; Pineda B; Ordóñez G; Ortiz-Plata A; Granados-Soto V; Sotelo J
    Neurology; 2011 Sep; 77(10):987-95. PubMed ID: 21865574
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Retinoic acid enhances TRAIL-induced apoptosis in cancer cells by upregulating TRAIL receptor 1 expression.
    Dhandapani L; Yue P; Ramalingam SS; Khuri FR; Sun SY
    Cancer Res; 2011 Aug; 71(15):5245-54. PubMed ID: 21685476
    [TBL] [Abstract] [Full Text] [Related]  


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