BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND SMAD3, JV15-2, 4088, ENSG00000166949, P84022, Smad3, MADH3, HsT17436, Smad 3, DKFZp686J10186, HSPC193, DKFZP586N0721, MGC60396 AND Treatment
88 results:

  • 1. Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in smad3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer.
    Han F; Chen S; Zhang K; Zhang K; Wang M; Wang P
    J Transl Med; 2024 Mar; 22(1):288. PubMed ID: 38493128
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. TGF-β1/smad3-driven GLI2 isoform expression contributes to aggressive phenotypes of hepatocellular carcinoma.
    Ding J; Yang YY; Li PT; Ma Y; Zhang L; Zhou Y; Jin C; Li HY; Zhu YF; Liu XP; Liu ZJ; Jia HL; Liu PG; Wu J
    Cancer Lett; 2024 Apr; 588():216768. PubMed ID: 38453045
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art.
    Lu G; Wang X; Cheng M; Wang S; Ma K
    Biomed Pharmacother; 2023 Sep; 165():115132. PubMed ID: 37423169
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. FOXA1-induced LINC00621 promotes lung adenocarcinoma progression via activating the TGF-β signaling pathway.
    Wei J; Yu H; Liu T; Wang Z; Lang C; Pan Y
    Thorac Cancer; 2023 Jul; 14(21):2026-2037. PubMed ID: 37277890
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Epigenetic regulation of smad3 by histone methyltransferase SMYD2 promotes lung cancer metastasis.
    Kim K; Ryu TY; Jung E; Han TS; Lee J; Kim SK; Roh YN; Lee MS; Jung CR; Lim JH; Hamamoto R; Lee HW; Hur K; Son MY; Kim DS; Cho HS
    Exp Mol Med; 2023 May; 55(5):952-964. PubMed ID: 37121971
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Knockdown of LINC00511 enhances radiosensitivity of lung adenocarcinoma via regulating miR-497-5p/smad3.
    Li C; Fu Y; He Y; Huang N; Yue J; Miao Y; Lv J; Xiao Y; Deng R; Zhang C; Huang M
    Cancer Biol Ther; 2023 Dec; 24(1):2165896. PubMed ID: 36861928
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. ATOH8 binds smad3 to induce cellular senescence and prevent Ras-driven malignant transformation.
    Liu X; Li X; Wang S; Liu Q; Feng X; Wang W; Huang Z; Huang Y; Wu J; Cai M; Cai X; Xu X; Cai J; Li M
    Proc Natl Acad Sci U S A; 2023 Jan; 120(3):e2208927120. PubMed ID: 36626550
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma.
    Xu W; Chen L; Liu J; Zhang Z; Wang R; Zhang Q; Li H; Xiang J; Fang L; Xu P; Li Z
    Cell Death Dis; 2022 Sep; 13(9):772. PubMed ID: 36071042
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Uncovering the dynamic effects of DEX treatment on lung cancer by integrating bioinformatic inference and multiscale modeling of scRNA-seq and proteomics data.
    Chen M; Xu C; Xu Z; He W; Zhang H; Su J; Song Q
    Comput Biol Med; 2022 Oct; 149():105999. PubMed ID: 35998480
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-β/smad3 pathway.
    Zhang T; Xia W; Song X; Mao Q; Huang X; Chen B; Liang Y; Wang H; Chen Y; Yu X; Zhang Z; Yang W; Xu L; Dong G; Jiang F
    J Hematol Oncol; 2022 Aug; 15(1):114. PubMed ID: 35982471
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. RNA
    Tan B; Zhou K; Liu W; Prince E; Qing Y; Li Y; Han L; Qin X; Su R; Pokharel SP; Yang L; Zhao Z; Shen C; Li W; Chen Z; Zhang Z; Deng X; Small A; Wang K; Leung K; Chen CW; Shen B; Chen J
    Theranostics; 2022; 12(13):5727-5743. PubMed ID: 35966596
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. APEX1 regulates alternative splicing of key tumorigenesis genes in non-small-cell lung cancer.
    Peng L; Liu Y; Chen J; Cheng M; Wu Y; Chen M; Zhong Y; Shen D; Chen L; Ye X
    BMC Med Genomics; 2022 Jul; 15(1):147. PubMed ID: 35780128
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Tumor in the Crossfire: Inhibiting TGF-β to Enhance cancer Immunotherapy.
    Tschernia NP; Gulley JL
    BioDrugs; 2022 Mar; 36(2):153-180. PubMed ID: 35353346
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma.
    Dong C; Wu K; Gu S; Wang W; Xie S; Zhou Y
    Cell Cycle; 2022 Jul; 21(13):1406-1421. PubMed ID: 35323096
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Recombinant human endostatin combined with radiotherapy promotes cardiomyocyte apoptosis in rats via TGFβ1/smads/CTGF signaling pathway.
    Ouyang W; Fu S; Zhao X; Su S; Zhang J; Luo D; Liu L; Ding W; Cao D; Liu L; He Z; Lu B
    BMC Cardiovasc Disord; 2022 Mar; 22(1):97. PubMed ID: 35279096
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Tetraethylthiuram disulphide alleviates pulmonary fibrosis through modulating transforming growth factor-β signalling.
    Jiang H; Zhao Y; Tang H; Duan S; Li M; Yang X; Liu J; Lou X; Cai Y; Zhao W; Sun L; Qian F
    Pharmacol Res; 2021 Dec; 174():105923. PubMed ID: 34607006
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. USP7 facilitates smad3 autoregulation to repress cancer progression in p53-deficient lung cancer.
    Huang YT; Cheng AC; Tang HC; Huang GC; Cai L; Lin TH; Wu KJ; Tseng PH; Wang GG; Chen WY
    Cell Death Dis; 2021 Sep; 12(10):880. PubMed ID: 34580281
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. PTTG1 knockdown enhances radiation-induced antitumour immunity in lung adenocarcinoma.
    Chen Z; Cao K; Hou Y; Lu F; Li L; Wang L; Xia Y; Zhang L; Chen H; Li R; Chang L; Li W
    Life Sci; 2021 Jul; 277():119594. PubMed ID: 33984357
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. ATAD2 interacts with C/EBPβ to promote esophageal squamous cell carcinoma metastasis via TGF-β1/smad3 signaling.
    Cao LJ; Zhang YJ; Dong SQ; Li XZ; Tong XT; Chen D; Wu ZY; Zheng XH; Xue WQ; Jia WH; Zhang JB
    J Exp Clin Cancer Res; 2021 Mar; 40(1):109. PubMed ID: 33757572
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The effects of the miR-21/smad7/TGF-β pathway on Th17 cell differentiation in COPD.
    He S; Sun S; Lu J; Chen L; Mei X; Li L; Zeng Z; Zhong M; Xie L
    Sci Rep; 2021 Mar; 11(1):6338. PubMed ID: 33739023
    [TBL] [Abstract] [Full Text] [Related]  


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