BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx AND Treatment
34 results:

  • 1. Congenital peribronchial myofibroblastic tumor (CPMT): a case report with long term follow-up and next-generation sequencing (NGS).
    Zhou P; Li S; Wang W; Tang Y; Jiang L
    BMC Pediatr; 2023 Apr; 23(1):184. PubMed ID: 37081446
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. ASPM Activates Hedgehog and Wnt Signaling to Promote Small Cell lung cancer Stemness and Progression.
    Cheng LH; Hsu CC; Tsai HW; Liao WY; Yang PM; Liao TY; Hsieh HY; Chan TS; Tsai KK
    Cancer Res; 2023 Mar; 83(6):830-844. PubMed ID: 36638332
    [TBL] [Abstract] [Full Text] [Related]  

  • 3.
    Ji W; Niu X; Yu Y; Li Z; Gu L; Lu S
    Front Immunol; 2022; 13():955800. PubMed ID: 36405701
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Jervine inhibits non-small cell lung cancer (NSCLC) progression by suppressing Hedgehog and AKT signaling via triggering autophagy-regulated apoptosis.
    Lei W; Huo Z
    Biochem Biophys Res Commun; 2020 Dec; 533(3):397-403. PubMed ID: 32972750
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Combined inhibition of JAK2-STAT3 and smo-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
    Doheny D; Sirkisoon S; Carpenter RL; Aguayo NR; Regua AT; Anguelov M; Manore SG; Arrigo A; Jalboush SA; Wong GL; Yu Y; Wagner CJ; Chan M; Ruiz J; Thomas A; Strowd R; Lin J; Lo HW
    Oncogene; 2020 Oct; 39(42):6589-6605. PubMed ID: 32929154
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Scutellariabarbata D. Don extraction selectively targets stemness-prone NSCLC cells by attenuating SOX2/smo/GLI1 network loop.
    Chen WW; Gong KK; Yang LJ; Dai JJ; Zhang Q; Wang F; Li XL; Xi SC; Du J
    J Ethnopharmacol; 2021 Jan; 265():113295. PubMed ID: 32841701
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The inhibition of microRNA-326 by SP1/HDAC1 contributes to proliferation and metastasis of osteosarcoma through promoting smo expression.
    Huang JH; Xu Y; Lin FY
    J Cell Mol Med; 2020 Sep; 24(18):10876-10888. PubMed ID: 32743904
    [TBL] [Abstract] [Full Text] [Related]  

  • 8.
    Jo E; Jang HJ; Shen L; Yang KE; Jang MS; Huh YH; Yoo HS; Park J; Jang IS; Park SJ
    Integr Cancer Ther; 2020; 19():1534735420923756. PubMed ID: 32456485
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
    Katoh M
    Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. HERC4 exerts an anti-tumor role through destabilizing the oncoprotein smo.
    Sun X; Sun B; Cui M; Zhou Z
    Biochem Biophys Res Commun; 2019 Jun; 513(4):1013-1018. PubMed ID: 31010679
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Triptonide inhibits lung cancer cell tumorigenicity by selectively attenuating the Shh-Gli1 signaling pathway.
    Zhang M; Tan S; Yu D; Zhao Z; Zhang B; Zhang P; Lv C; Zhou Q; Cao Z
    Toxicol Appl Pharmacol; 2019 Feb; 365():1-8. PubMed ID: 30610878
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Vismodegib.
    Meiss F; Andrlová H; Zeiser R
    Recent Results Cancer Res; 2018; 211():125-139. PubMed ID: 30069764
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Antitumor Efficacy of Dual Blockade of EGFR Signaling by Osimertinib in Combination With Selumetinib or Cetuximab in Activated EGFR Human NCLC Tumor Models.
    Della Corte CM; Ciaramella V; Cardone C; La Monica S; Alfieri R; Petronini PG; Malapelle U; Vigliar E; Pepe F; Troncone G; Castellone MD; Troiani T; Martinelli E; Ciardiello F; Morgillo F
    J Thorac Oncol; 2018 Jun; 13(6):810-820. PubMed ID: 29526823
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Inhibition of Gli leads to antitumor growth and enhancement of cisplatin-induced cytotoxicity in large cell neuroendocrine carcinoma of the lung.
    Ishiwata T; Iwasawa S; Ebata T; Fan M; Tada Y; Tatsumi K; Takiguchi Y
    Oncol Rep; 2018 Mar; 39(3):1148-1154. PubMed ID: 29328464
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. [Preliminary study of exon sequence in pneumoconiosis and pneumoconiosis complicated with lung cancer using high-throughput sequencing technology].
    Jiang MF; Li L; Wang Z; Zhang CL; Zhang H
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi; 2017 Nov; 35(11):801-806. PubMed ID: 29316748
    [No Abstract]    [Full Text] [Related]  

  • 16. The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
    Skoda AM; Simovic D; Karin V; Kardum V; Vranic S; Serman L
    Bosn J Basic Med Sci; 2018 Feb; 18(1):8-20. PubMed ID: 29274272
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP treatment.
    Du J; Chen W; Yang L; Dai J; Guo J; Wu Y; Gong K; Zhang J; Yu N; Xie Z; Xi S
    Sci Rep; 2017 May; 7(1):1899. PubMed ID: 28507311
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Efficacy of continuous EGFR-inhibition and role of Hedgehog in EGFR acquired resistance in human lung cancer cells with activating mutation of EGFR.
    Della Corte CM; Malapelle U; Vigliar E; Pepe F; Troncone G; Ciaramella V; Troiani T; Martinelli E; Belli V; Ciardiello F; Morgillo F
    Oncotarget; 2017 Apr; 8(14):23020-23032. PubMed ID: 28416737
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. MiRNA-Related Genetic Variations Associated with Radiotherapy-Induced Toxicities in Patients with Locally Advanced Non-Small Cell lung cancer.
    Li R; Pu X; Chang JY; Ye Y; Komaki R; Minna JD; Roth JA; Han B; Wu X
    PLoS One; 2016; 11(3):e0150467. PubMed ID: 26991123
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Blockade of Hedgehog Signaling Synergistically Increases Sensitivity to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell lung cancer Cell Lines.
    Bai XY; Zhang XC; Yang SQ; An SJ; Chen ZH; Su J; Xie Z; Gou LY; Wu YL
    PLoS One; 2016; 11(3):e0149370. PubMed ID: 26943330
    [TBL] [Abstract] [Full Text] [Related]  


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