BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND STAT3, FLJ20882, 6774, ENSG00000168610, APRF, P40763, MGC16063 AND Treatment
631 results:

  • 1. Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models.
    Salembier R; De Haes C; Bellemans J; Demeyere K; Van Den Broeck W; Sanders NN; Van Laere S; Lyons TR; Meyer E; Steenbrugge J
    Breast Cancer Res; 2024 Apr; 26(1):63. PubMed ID: 38605414
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent stat3-K631 acetylation and its Y705-phosphorylation.
    Ge W; Li YA; Ruan Y; Wu N; Ma P; Xu T; Shu Y; Wang Y; Qiu W; Zhao C
    Oncol Res; 2024; 32(4):625-641. PubMed ID: 38560562
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Anlotinib Inhibits Cisplatin Resistance in Non-Small-Cell lung cancer Cells by Inhibiting MCL-1 Expression via MET/stat3/Akt Pathway.
    Wang L; Xu L; Han S; Zhu X
    Can Respir J; 2024; 2024():2632014. PubMed ID: 38468814
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Emerging role of tumor suppressing microRNAs as therapeutics in managing non-small cell lung cancer.
    Singh S; Saxena S; Sharma H; Paudel KR; Chakraborty A; MacLoughlin R; Oliver BG; Gupta G; Negi P; Singh SK; Dua K
    Pathol Res Pract; 2024 Apr; 256():155222. PubMed ID: 38452582
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. 5-Methoxytryptophan enhances the sensitivity of sorafenib on the inhibition of proliferation and metastasis for lung cancer cells.
    Chen HC; Kuo CY; Chang Y; Tsai DL; Lee MH; Lee JY; Lee HM; Su YC
    BMC Cancer; 2024 Feb; 24(1):248. PubMed ID: 38388902
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A coumarin-furoxan hybrid as novel nitric oxide donor induced cell apoptosis and ferroptosis in NSCLC by promoting S-nitrosylation of stat3 and negative regulation of JAK2-stat3 pathway.
    Cao F; Li M; Wang W; Yi Y; Chen Y; Liu H
    Biochem Pharmacol; 2024 Apr; 222():116068. PubMed ID: 38387529
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. MiR-320a upregulation contributes to the effectiveness of pemetrexed by inhibiting the growth and invasion of human lung cancer cell line (Calu-6).
    Ghorbani Alvanegh A; Arpanaei A; Esmaeili Gouvarchin Ghaleh H; Mohammad Ganji S
    Mol Biol Rep; 2024 Feb; 51(1):310. PubMed ID: 38372812
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial.
    Besse B; Pons-Tostivint E; Park K; Hartl S; Forde PM; Hochmair MJ; Awad MM; Thomas M; Goss G; Wheatley-Price P; Shepherd FA; Florescu M; Cheema P; Chu QSC; Kim SW; Morgensztern D; Johnson ML; Cousin S; Kim DW; Moskovitz MT; Vicente D; Aronson B; Hobson R; Ambrose HJ; Khosla S; Reddy A; Russell DL; Keddar MR; Conway JP; Barrett JC; Dean E; Kumar R; Dressman M; Jewsbury PJ; Iyer S; Barry ST; Cosaert J; Heymach JV
    Nat Med; 2024 Mar; 30(3):716-729. PubMed ID: 38351187
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment.
    Deng Y; Chen Q; Yang X; Sun Y; Zhang B; Wei W; Deng S; Meng J; Hu Y; Wang Y; Zhang Z; Wen L; Huang F; Wan C; Yang K
    Theranostics; 2024; 14(3):1224-1240. PubMed ID: 38323313
    [No Abstract]    [Full Text] [Related]  

  • 10. Antibody-Drug Conjugate αEGFR-E-P125A Reduces Triple-negative Breast cancer Vasculogenic Mimicry, Motility, and Metastasis through Inhibition of EGFR, Integrin, and FAK/stat3 Signaling.
    Sankar AP; Cho HM; Shin SU; Sneh T; Ramakrishnan S; Elledge C; Zhang Y; Das R; Gil-Henn H; Rosenblatt JD
    Cancer Res Commun; 2024 Mar; 4(3):738-756. PubMed ID: 38315147
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Network pharmacology study to explore the multiple molecular mechanism of SH003 in the treatment of non-small cell lung cancer.
    Lee K; Choi YJ; Lim HI; Cho KJ; Kang N; Ko SG
    BMC Complement Med Ther; 2024 Feb; 24(1):70. PubMed ID: 38303001
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The Ethanolic Extract of
    Park HJ; Park SH
    Nutr Cancer; 2024; 76(3):305-315. PubMed ID: 38185896
    [No Abstract]    [Full Text] [Related]  

  • 13. The role of tumor-associated macrophages in lung cancer: From mechanism to small molecule therapy.
    Zhou Y; Qian M; Li J; Ruan L; Wang Y; Cai C; Gu S; Zhao X
    Biomed Pharmacother; 2024 Jan; 170():116014. PubMed ID: 38134634
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Shenqi Fuzheng injection restores the sensitivity to gefitinib in non-small cell lung cancer by inhibiting the IL-22/stat3/AKT pathway.
    Wang J; He X; Jia Z; Yan A; Xiao K; Liu S; Hou M; Long Y; Ding X
    Pharm Biol; 2024 Dec; 62(1):33-41. PubMed ID: 38100532
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells.
    Xia L; Liu JY; Yang MY; Zhang XH; Jiang Y; Yin QQ; Luo CH; Liu HC; Kang ZJ; Zhang CT; Gao BB; Zhou AW; Cai HY; Waller EK; Yan JS; Lu Y
    Cancer Res; 2024 Feb; 84(3):479-492. PubMed ID: 38095536
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the ErbB3/stat3 signaling pathway.
    Liu YN; Tsai MF; Wu SG; Chang TH; Shih JY
    Life Sci; 2024 Jan; 336():122345. PubMed ID: 38092140
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. KRAS G12C-mutant driven non-small cell lung cancer (NSCLC).
    Rosell R; Codony-Servat J; González J; Santarpia M; Jain A; Shivamallu C; Wang Y; Giménez-Capitán A; Molina-Vila MA; Nilsson J; González-Cao M
    Crit Rev Oncol Hematol; 2024 Mar; 195():104228. PubMed ID: 38072173
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. 3,3',5,5'-Tetramethoxybiphenyl-4,4'diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line.
    Concato-Lopes VM; Silva TF; Detoni MB; Cruz EMS; Gonçalves MD; da Silva Bortoleti BT; Tomiotto-Pellissier F; Carloto ACM; Madureira MB; Rodrigues ACJ; Schirmann JG; Barbosa-Dekker AM; Dekker RFH; Conchon-Costa I; Panis C; Lazarin-Bidóia D; Miranda-Sapla MM; Mantovani MS; Pavanelli WR
    Biomed Pharmacother; 2024 Jan; 170():115979. PubMed ID: 38061138
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Identification of Bulbocodin D and C as novel stat3 inhibitors and their anticancer activities in lung cancer cells.
    He X; Fu J; Lyu W; Huang M; Mo J; Cheng Y; Xu Y; Zheng L; Zhang X; Qi L; Zhang L; Zheng Y; Huang M; Ni L; Lu J
    Chin J Nat Med; 2023 Nov; 21(11):842-851. PubMed ID: 38035939
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/stat3 in NSCLC.
    Song X; Wang L; Tang W; Yuan L; Liu Q; Li J; Fan D
    Arch Pharm Res; 2023 Dec; 46(11-12):924-938. PubMed ID: 38032449
    [TBL] [Abstract] [Full Text] [Related]  


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