BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND TET2, Q6N021, MGC125715, KIAA1546, FLJ20032, ENSG00000168769, 54790
43 results:

  • 1. Tet methylcytosine dioxygenase 2 (tet2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer.
    Zhang J; Zhao K; Zhou W; Kang R; Wei S; Shu Y; Yu C; Ku Y; Mao Y; Luo H; Yang J; Mei J; Pu Q; Deng S; Zha Z; Yuan G; Shen S; Chen Y; Liu L
    Signal Transduct Target Ther; 2024 Mar; 9(1):65. PubMed ID: 38461173
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Comprehensive Genomic Analysis of Patients With Non-Small-Cell lung cancer Using Blood-Based Circulating Tumor DNA Assay: Findings From the BFAST Database of a Single Center in Taiwan.
    Wang HY; Ho CC; Lin YT; Liao WY; Chen CY; Shih JY; Yu CJ
    JCO Precis Oncol; 2024 Jan; 8():e2300314. PubMed ID: 38190582
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Mesothelioma in situ of the peritoneum: report of three cases and review of the literature.
    Symes E; Tjota M; Cody B; Kindler H; Mitchell O; Witmer H; Turaga K; Mueller J; Krausz T; Husain AN; Li H
    Histopathology; 2024 Feb; 84(3):492-506. PubMed ID: 38084880
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Effects of IL-1β inhibition on anemia and clonal hematopoiesis in the randomized CANTOS trial.
    Woo J; Lu D; Lewandowski A; Xu H; Serrano P; Healey M; Yates DP; Beste MT; Libby P; Ridker PM; Steensma DP
    Blood Adv; 2023 Dec; 7(24):7471-7484. PubMed ID: 37934948
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing.
    Jakubek YA; Zhou Y; Stilp A; Bacon J; Wong JW; Ozcan Z; Arnett D; Barnes K; Bis JC; Boerwinkle E; Brody JA; Carson AP; Chasman DI; Chen J; Cho M; Conomos MP; Cox N; Doyle MF; Fornage M; Guo X; Kardia SLR; Lewis JP; Loos RJF; Ma X; Machiela MJ; Mack TM; Mathias RA; Mitchell BD; Mychaleckyj JC; North K; Pankratz N; Peyser PA; Preuss MH; Psaty B; Raffield LM; Vasan RS; Redline S; Rich SS; Rotter JI; Silverman EK; Smith JA; Smith AP; Taub M; Taylor KD; Yun J; Li Y; Desai P; Bick AG; Reiner AP; Scheet P; Auer PL
    Nat Genet; 2023 Nov; 55(11):1912-1919. PubMed ID: 37904051
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. DNA dioxygenases tet2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell.
    Zeng Z; Li T; Liu X; Ma Y; Luo L; Wang Z; Zhao Z; Li H; He X; Zeng H; Tao Y; Chen Y
    Redox Biol; 2023 Nov; 67():102916. PubMed ID: 37812881
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk.
    Tobias DK; Manning AK; Wessel J; Raghavan S; Westerman KE; Bick AG; Dicorpo D; Whitsel EA; Collins J; Correa A; Cupples LA; Dupuis J; Goodarzi MO; Guo X; Howard B; Lange LA; Liu S; Raffield LM; Reiner AP; Rich SS; Taylor KD; Tinker L; Wilson JG; Wu P; Carson AP; Vasan RS; Fornage M; Psaty BM; Kooperberg C; Rotter JI; Meigs J; Manson JE;
    Diabetes Care; 2023 Nov; 46(11):1978-1985. PubMed ID: 37756531
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. tet2 inhibits the proliferation and metastasis of lung adenocarcinoma cells via activation of the cGAS-STING signalling pathway.
    Cheng G; Wu J; Ji M; Hu W; Wu C; Jiang J
    BMC Cancer; 2023 Sep; 23(1):825. PubMed ID: 37667220
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
    Yu Z; Fidler TP; Ruan Y; Vlasschaert C; Nakao T; Uddin MM; Mack T; Niroula A; Heimlich JB; Zekavat SM; Gibson CJ; Griffin GK; Wang Y; Peloso GM; Heard-Costa N; Levy D; Vasan RS; Aguet F; Ardlie KG; Taylor KD; Rich SS; Rotter JI; Libby P; Jaiswal S; Ebert BL; Bick AG; Tall AR; Natarajan P
    J Clin Invest; 2023 Sep; 133(18):. PubMed ID: 37498674
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Cerebrospinal fluid as a liquid biopsy for molecular characterization of brain metastasis in patients with non-small cell lung cancer.
    Tsakonas G; Tadigotla V; Chakrabortty SK; Stragliotto G; Chan D; Lewensohn R; Yu W; Skog JK; Hydbring P; Ekman S
    Lung Cancer; 2023 Aug; 182():107292. PubMed ID: 37423059
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease.
    Gumuser ED; Schuermans A; Cho SMJ; Sporn ZA; Uddin MM; Paruchuri K; Nakao T; Yu Z; Haidermota S; Hornsby W; Weeks LD; Niroula A; Jaiswal S; Libby P; Ebert BL; Bick AG; Natarajan P; Honigberg MC
    J Am Coll Cardiol; 2023 May; 81(20):1996-2009. PubMed ID: 37197843
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Review of clonal hematopoiesis, subtypes and its role in neoplasia and different morbidities.
    Younes IE; Syler L; Hamed A
    Leuk Res; 2023 Jul; 130():107307. PubMed ID: 37186988
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
    Weinstock JS; Gopakumar J; Burugula BB; Uddin MM; Jahn N; Belk JA; Bouzid H; Daniel B; Miao Z; Ly N; Mack TM; Luna SE; Prothro KP; Mitchell SR; Laurie CA; Broome JG; Taylor KD; Guo X; Sinner MF; von Falkenhausen AS; Kääb S; Shuldiner AR; O'Connell JR; Lewis JP; Boerwinkle E; Barnes KC; Chami N; Kenny EE; Loos RJF; Fornage M; Hou L; Lloyd-Jones DM; Redline S; Cade BE; Psaty BM; Bis JC; Brody JA; Silverman EK; Yun JH; Qiao D; Palmer ND; Freedman BI; Bowden DW; Cho MH; DeMeo DL; Vasan RS; Yanek LR; Becker LC; Kardia SLR; Peyser PA; He J; Rienstra M; Van der Harst P; Kaplan R; Heckbert SR; Smith NL; Wiggins KL; Arnett DK; Irvin MR; Tiwari H; Cutler MJ; Knight S; Muhlestein JB; Correa A; Raffield LM; Gao Y; de Andrade M; Rotter JI; Rich SS; Tracy RP; Konkle BA; Johnsen JM; Wheeler MM; Smith JG; Melander O; Nilsson PM; Custer BS; Duggirala R; Curran JE; Blangero J; McGarvey S; Williams LK; Xiao S; Yang M; Gu CC; Chen YI; Lee WJ; Marcus GM; Kane JP; Pullinger CR; Shoemaker MB; Darbar D; Roden DM; Albert C; Kooperberg C; Zhou Y; Manson JE; Desai P; Johnson AD; Mathias RA; ; Blackwell TW; Abecasis GR; Smith AV; Kang HM; Satpathy AT; Natarajan P; Kitzman JO; Whitsel EA; Reiner AP; Bick AG; Jaiswal S
    Nature; 2023 Apr; 616(7958):755-763. PubMed ID: 37046083
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Evaluation of TET Family Gene Expression and 5-Hydroxymethylcytosine as Potential Epigenetic Markers in Non-small Cell lung cancer.
    Alrehaili AA; Gharib AF; Alghamdi SA; Alhazmi A; Al-Shehri SS; Hagag HM; Alsaeedi FA; Alhuthali HM; Raafat N; Etewa RL; Elsawy WH
    In Vivo; 2023; 37(1):445-453. PubMed ID: 36593050
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Clonal hematopoiesis confers an increased mortality risk in orthotopic heart transplant recipients.
    Scolari FL; Brahmbhatt DH; Abelson S; Medeiros JJF; Anker MS; Fung NL; Otsuki M; Calvillo-Argüelles O; Lawler PR; Ross HJ; Luk AC; Anker S; Dick JE; Billia F
    Am J Transplant; 2022 Dec; 22(12):3078-3086. PubMed ID: 35971851
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock.
    Scolari FL; Abelson S; Brahmbhatt DH; Medeiros JJF; Fan CS; Fung NL; Mihajlovic V; Anker MS; Otsuki M; Lawler PR; Ross HJ; Luk AC; Anker S; Dick JE; Billia F
    Eur J Heart Fail; 2022 Sep; 24(9):1573-1582. PubMed ID: 35729851
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. A macaque clonal hematopoiesis model demonstrates expansion of tet2-disrupted clones and utility for testing interventions.
    Shin TH; Zhou Y; Chen S; Cordes S; Grice MZ; Fan X; Lee BC; Aljanahi AA; Hong SG; Vaughan KL; Mattison JA; Kohama SG; Fabre MA; Uchida N; Demirci S; Corat MAF; Métais JY; Calvo KR; Buscarlet M; Natanson H; McGraw KL; List AF; Busque L; Tisdale JF; Vassiliou GS; Yu KR; Dunbar CE
    Blood; 2022 Oct; 140(16):1774-1789. PubMed ID: 35714307
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
    Miller PG; Qiao D; Rojas-Quintero J; Honigberg MC; Sperling AS; Gibson CJ; Bick AG; Niroula A; McConkey ME; Sandoval B; Miller BC; Shi W; Viswanathan K; Leventhal M; Werner L; Moll M; Cade BE; Barr RG; Correa A; Cupples LA; Gharib SA; Jain D; Gogarten SM; Lange LA; London SJ; Manichaikul A; O'Connor GT; Oelsner EC; Redline S; Rich SS; Rotter JI; Ramachandran V; Yu B; Sholl L; Neuberg D; Jaiswal S; Levy BD; Owen CA; Natarajan P; Silverman EK; van Galen P; Tesfaigzi Y; Cho MH; Ebert BL;
    Blood; 2022 Jan; 139(3):357-368. PubMed ID: 34855941
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.
    Bhattacharya R; Zekavat SM; Haessler J; Fornage M; Raffield L; Uddin MM; Bick AG; Niroula A; Yu B; Gibson C; Griffin G; Morrison AC; Psaty BM; Longstreth WT; Bis JC; Rich SS; Rotter JI; Tracy RP; Correa A; Seshadri S; Johnson A; Collins JM; Hayden KM; Madsen TE; Ballantyne CM; Jaiswal S; Ebert BL; Kooperberg C; Manson JE; Whitsel EA; ; Natarajan P; Reiner AP
    Stroke; 2022 Mar; 53(3):788-797. PubMed ID: 34743536
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Non-Malignant Clonal Hematopoiesis.
    Dillon LW; Ghannam J; Nosiri C; Gui G; Goswami M; Calvo KR; Lindblad KE; Oetjen KA; Wilkerson MD; Soltis AR; Sukumar G; Dalgard CL; Thompson J; Valdez J; DeStefano CB; Lai C; Sciambi A; Durruthy-Durruthy R; Llanso A; Gulati S; Wang S; Ooi A; Dagur PK; McCoy JP; Burr P; Li Y; Hourigan CS
    Blood Cancer Discov; 2021 Jul; 2(4):319-325. PubMed ID: 34258102
    [TBL] [Abstract] [Full Text] [Related]  


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