Terms: = Lung cancer AND WHSC1L1, ENSG00000147548, 54904
10 results:
1. Identification of novel class inhibitors of NSD3 methyltransferase showing a unique, bivalent binding mode in the SET domain.
Kim S; Hwang I; Kim SH; Chung HW; Ji MJ; Moon S; Park HM; Kong G; Hur W
Chem Biol Drug Des; 2023 Sep; 102(3):500-513. PubMed ID: 37072259
[TBL] [Abstract] [Full Text] [Related]
2. Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.
Böttcher J; Dilworth D; Reiser U; Neumüller RA; Schleicher M; Petronczki M; Zeeb M; Mischerikow N; Allali-Hassani A; Szewczyk MM; Li F; Kennedy S; Vedadi M; Barsyte-Lovejoy D; Brown PJ; Huber KVM; Rogers CM; Wells CI; Fedorov O; Rumpel K; Zoephel A; Mayer M; Wunberg T; Böse D; Zahn S; Arnhof H; Berger H; Reiser C; Hörmann A; Krammer T; Corcokovic M; Sharps B; Winkler S; Häring D; Cockcroft XL; Fuchs JE; Müllauer B; Weiss-Puxbaum A; Gerstberger T; Boehmelt G; Vakoc CR; Arrowsmith CH; Pearson M; McConnell DB
Nat Chem Biol; 2019 Aug; 15(8):822-829. PubMed ID: 31285596
[TBL] [Abstract] [Full Text] [Related]
3. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies.
Li Z; Ivanov AA; Su R; Gonzalez-Pecchi V; Qi Q; Liu S; Webber P; McMillan E; Rusnak L; Pham C; Chen X; Mo X; Revennaugh B; Zhou W; Marcus A; Harati S; Chen X; Johns MA; White MA; Moreno C; Cooper LA; Du Y; Khuri FR; Fu H
Nat Commun; 2017 Feb; 8():14356. PubMed ID: 28205554
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4. Characterization of FGFR1 Locus in sqNSCLC Reveals a Broad and Heterogeneous Amplicon.
Rooney C; Geh C; Williams V; Heuckmann JM; Menon R; Schneider P; Al-Kadhimi K; Dymond M; Smith NR; Baker D; French T; Smith PD; Harrington EA; Barrett JC; Kilgour E
PLoS One; 2016; 11(2):e0149628. PubMed ID: 26905262
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5. Mutation spectra of histone methyltransferases with canonical SET domains and EZH2-targeted therapy.
Katoh M
Epigenomics; 2016 Feb; 8(2):285-305. PubMed ID: 26411517
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6. PPAPDC1B and whsc1l1 are common drivers of the 8p11-12 amplicon, not only in breast tumors but also in pancreatic adenocarcinomas and lung tumors.
Mahmood SF; Gruel N; Nicolle R; Chapeaublanc E; Delattre O; Radvanyi F; Bernard-Pierrot I
Am J Pathol; 2013 Nov; 183(5):1634-1644. PubMed ID: 24051013
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7. The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (whsc1l1) is involved in human carcinogenesis.
Kang D; Cho HS; Toyokawa G; Kogure M; Yamane Y; Iwai Y; Hayami S; Tsunoda T; Field HI; Matsuda K; Neal DE; Ponder BA; Maehara Y; Nakamura Y; Hamamoto R
Genes Chromosomes Cancer; 2013 Feb; 52(2):126-39. PubMed ID: 23011637
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8. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.
Dutt A; Ramos AH; Hammerman PS; Mermel C; Cho J; Sharifnia T; Chande A; Tanaka KE; Stransky N; Greulich H; Gray NS; Meyerson M
PLoS One; 2011; 6(6):e20351. PubMed ID: 21666749
[TBL] [Abstract] [Full Text] [Related]
9. The NSD3L histone methyltransferase regulates cell cycle and cell invasion in breast cancer cells.
Zhou Z; Thomsen R; Kahns S; Nielsen AL
Biochem Biophys Res Commun; 2010 Jul; 398(3):565-70. PubMed ID: 20599755
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10. High-resolution genomic profiles of human lung cancer.
Tonon G; Wong KK; Maulik G; Brennan C; Feng B; Zhang Y; Khatry DB; Protopopov A; You MJ; Aguirre AJ; Martin ES; Yang Z; Ji H; Chin L; Depinho RA
Proc Natl Acad Sci U S A; 2005 Jul; 102(27):9625-30. PubMed ID: 15983384
[TBL] [Abstract] [Full Text] [Related]
