Terms: = Lung cancer AND XPA, XPAC, 7507, ENSG00000136936, XP1, P23025 AND Treatment
18 results:
1. Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints.
Kong YW; Dreaden EC; Morandell S; Zhou W; Dhara SS; Sriram G; Lam FC; Patterson JC; Quadir M; Dinh A; Shopsowitz KE; Varmeh S; Yilmaz ÖH; Lippard SJ; Reinhardt HC; Hemann MT; Hammond PT; Yaffe MB
Nat Commun; 2020 Aug; 11(1):4124. PubMed ID: 32807787
[TBL] [Abstract] [Full Text] [Related]
2. Increased levels of xpa might be the basis of cisplatin resistance in germ cell tumours.
Cierna Z; Miskovska V; Roska J; Jurkovicova D; Pulzova LB; Sestakova Z; Hurbanova L; Machalekova K; Chovanec M; Rejlekova K; Svetlovska D; Kalavska K; Kajo K; Babal P; Mardiak J; Ward TA; Mego M; Chovanec M
BMC Cancer; 2020 Jan; 20(1):17. PubMed ID: 31906898
[TBL] [Abstract] [Full Text] [Related]
3. Genetic Polymorphisms and Platinum-based Chemotherapy treatment Outcomes in Patients with Non-Small Cell lung cancer: A Genetic Epidemiology Study Based Meta-analysis.
Tan LM; Qiu CF; Zhu T; Jin YX; Li X; Yin JY; Zhang W; Zhou HH; Liu ZQ
Sci Rep; 2017 Jul; 7(1):5593. PubMed ID: 28717179
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4. Exposure of Human lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pathway.
Holcomb N; Goswami M; Han SG; Clark S; Orren DK; Gairola CG; Mellon I
PLoS One; 2016; 11(7):e0158858. PubMed ID: 27391141
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5. Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock.
Choi JY; Joh HM; Park JM; Kim MJ; Chung TH; Kang TH
Oncotarget; 2016 May; 7(22):32980-9. PubMed ID: 27145275
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6. The relationship between polymorphisms of genes regulating DNA repair or cell division and the toxicity of platinum and vinorelbine chemotherapy in advanced NSCLC patients.
Powrózek T; Mlak R; Krawczyk P; Homa I; Ciesielka M; Kozioł P; Prendecka M; Milanowski J; Małecka-Massalska T
Clin Transl Oncol; 2016 Feb; 18(2):125-31. PubMed ID: 26193985
[TBL] [Abstract] [Full Text] [Related]
7. TP53 mutations induced by BPDE in xpa-WT and xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Kucab JE; van Steeg H; Luijten M; Schmeiser HH; White PA; Phillips DH; Arlt VM
Mutat Res; 2015 Mar; 773():48-62. PubMed ID: 25847421
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8. Pharmacogenetics of the DNA repair pathways in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.
Sullivan I; Salazar J; Majem M; Pallarés C; Del Río E; Páez D; Baiget M; Barnadas A
Cancer Lett; 2014 Oct; 353(2):160-6. PubMed ID: 25069034
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9. Predictive effect of xpa and XPD polymorphisms on survival of advanced NSCLC patients treated with platinum-based chemotherapy: a three-dimensional (3-D), polyacrylamide gel-based DNA microarray method.
Cheng H; Qin Q; Sun X; Li F; Sun N; Cheng L; Lu Z; Chen B
Technol Cancer Res Treat; 2013 Oct; 12(5):473-82. PubMed ID: 23617284
[TBL] [Abstract] [Full Text] [Related]
10. xpa-210: a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma.
Gakis G; Hennenlotter J; Scharpf M; Hevler J; Schilling D; Kuehs U; Stenzl A; Schwentner C
World J Urol; 2011 Dec; 29(6):801-6. PubMed ID: 21113600
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11. Antimony impairs nucleotide excision repair: xpa and XPE as potential molecular targets.
Grosskopf C; Schwerdtle T; Mullenders LH; Hartwig A
Chem Res Toxicol; 2010 Jul; 23(7):1175-83. PubMed ID: 20509621
[TBL] [Abstract] [Full Text] [Related]
12. UV light killing efficacy of fluorescent protein-expressing cancer cells in vitro and in vivo.
Kimura H; Lee C; Hayashi K; Yamauchi K; Yamamoto N; Tsuchiya H; Tomita K; Bouvet M; Hoffman RM
J Cell Biochem; 2010 Aug; 110(6):1439-46. PubMed ID: 20506255
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13. xpa A23G polymorphism is associated with the elevated response to platinum-based chemotherapy in advanced non-small cell lung cancer.
Feng J; Sun X; Sun N; Qin S; Li F; Cheng H; Chen B; Cao Y; Ma J; Cheng L; Lu Z; Ji J; Zhou Y
Acta Biochim Biophys Sin (Shanghai); 2009 May; 41(5):429-35. PubMed ID: 19430706
[TBL] [Abstract] [Full Text] [Related]
14. ATR-dependent checkpoint modulates xpa nuclear import in response to UV irradiation.
Wu X; Shell SM; Liu Y; Zou Y
Oncogene; 2007 Feb; 26(5):757-64. PubMed ID: 16862173
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15. A truncated human xeroderma pigmentosum complementation group A protein expressed from an adenovirus sensitizes human tumor cells to ultraviolet light and cisplatin.
Rosenberg E; Taher MM; Kuemmerle NB; Farnsworth J; Valerie K
Cancer Res; 2001 Jan; 61(2):764-70. PubMed ID: 11212280
[TBL] [Abstract] [Full Text] [Related]
16. An investigation of the molecular basis for the synergistic interaction of tirapazamine and cisplatin.
Goldberg Z; Evans J; Birrell G; Brown JM
Int J Radiat Oncol Biol Phys; 2001 Jan; 49(1):175-82. PubMed ID: 11163512
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17. Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: association with attenuation of the interaction of xpa and ERCC1 nucleotide excision repair proteins.
Jiang H; Yang LY
Cancer Res; 1999 Sep; 59(18):4529-34. PubMed ID: 10493501
[TBL] [Abstract] [Full Text] [Related]
18. Heat-shock enhanced reactivation of a UV-damaged reporter gene in human cells involves the transcription coupled DNA repair pathway.
McKay BC; Rainbow AJ
Mutat Res; 1996 Jun; 363(2):125-35. PubMed ID: 8676926
[TBL] [Abstract] [Full Text] [Related]
