BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND XPO1, DKFZp686B1823, 7514, ENSG00000082898, O14980, CRM1
33 results:

  • 1. Multi-omics analysis reveals PUS1 triggered malignancy and correlated with immune infiltrates in NSCLC.
    Tan Y; Wang Z; Wang Y; Tian X; Huang Y; Wu G; Lu J
    Aging (Albany NY); 2023 Nov; 15(21):12136-12154. PubMed ID: 37925171
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Cisplatin Dependent Secretion of Immunomodulatory High Mobility Group Box 1 (HMGB1) Protein from lung cancer Cells.
    Gillespie KP; Pirnie R; Mesaros C; Blair IA
    Biomolecules; 2023 Aug; 13(9):. PubMed ID: 37759736
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. xpo1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma.
    Ye Y; Lv C; Sun J; Lin Z; Liu Y; Huang Y; Chen Y; Li H; Lian X; Jiang X; Zhang S; Wang S
    Oxid Med Cell Longev; 2022; 2022():1361135. PubMed ID: 36589683
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The efficacy of selinexor (KPT-330), an xpo1 inhibitor, on non-hematologic cancers: a comprehensive review.
    Landes JR; Moore SA; Bartley BR; Doan HQ; Rady PL; Tyring SK
    J Cancer Res Clin Oncol; 2023 May; 149(5):2139-2155. PubMed ID: 35941226
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Primary Soft Tissue Hydatid Cysts.
    Patmano M; Çetin DA; Gümüş T; Patmano G; Yenigül AE
    Turkiye Parazitol Derg; 2022 May; 46(2):145-149. PubMed ID: 35604194
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Inhibitor of the Nuclear Transport Protein xpo1 Enhances the Anticancer Efficacy of KRAS G12C Inhibitors in Preclinical Models of KRAS G12C-Mutant cancers.
    Khan HY; Nagasaka M; Li Y; Aboukameel A; Uddin MH; Sexton R; Bannoura S; Mzannar Y; Al-Hallak MN; Kim S; Beydoun R; Landesman Y; Mamdani H; Uprety D; Philip PA; Mohammad RM; Shields AF; Azmi AS
    Cancer Res Commun; 2022 May; 2(5):342-352. PubMed ID: 35573474
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inhibition of xpo1 Sensitizes Small Cell lung cancer to First- and Second-Line Chemotherapy.
    Quintanal-Villalonga A; Taniguchi H; Hao Y; Chow A; Zhan YA; Chavan SS; Uddin F; Allaj V; Manoj P; Shah NS; Chan JM; Offin M; Ciampricotti M; Ray-Kirton J; Egger J; Bhanot U; Linkov I; Asher M; Roehrl MH; Qiu J; de Stanchina E; Hollmann TJ; Koche RP; Sen T; Poirier JT; Rudin CM
    Cancer Res; 2022 Feb; 82(3):472-483. PubMed ID: 34815254
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Chromosome Region Maintenance 1 (xpo1/crm1) as an Anticancer Target and Discovery of Its Inhibitor.
    Liu S; Qiao W; Sun Q; Luo Y
    J Med Chem; 2021 Nov; 64(21):15534-15548. PubMed ID: 34669417
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Impact of xpo1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC).
    Nagasaka M; Asad MFB; Al Hallak MN; Uddin MH; Sukari A; Baca Y; Xiu J; Magee D; Mamdani H; Uprety D; Kim C; Xia B; Liu SV; Nieva JJ; Lopes G; Bepler G; Borghaei H; Demeure MJ; Raez LE; Ma PC; Puri S; Korn WM; Azmi AS
    Lung Cancer; 2021 Oct; 160():92-98. PubMed ID: 34482103
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. lung cancer screening by single-shot dual-energy subtraction using flat-panel detector.
    Mogami H; Onoike Y; Miyano H; Arakawa K; Inoue H; Sakae K; Kawakami T
    Jpn J Radiol; 2021 Dec; 39(12):1168-1173. PubMed ID: 34173973
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. xpo1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a.
    Wang J; Sun T; Meng Z; Wang L; Li M; Chen J; Qin T; Yu J; Zhang M; Bie Z; Dong Z; Jiang X; Lin L; Zhang C; Liu Z; Jiang R; Yang G; Li L; Zhang Y; Huang D
    Cancer Lett; 2021 Apr; 503():197-212. PubMed ID: 33493586
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A novel circular RNA, circxpo1, promotes lung adenocarcinoma progression by interacting with IGF2BP1.
    Huang Q; Guo H; Wang S; Ma Y; Chen H; Li H; Li J; Li X; Yang F; Qiu M; Zhao S; Wang J
    Cell Death Dis; 2020 Dec; 11(12):1031. PubMed ID: 33268793
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Comprehensive analyses of T-UCR expression profiles and exploration of the efficacy of uc.63- and uc.280+ as biomarkers for lung cancer in Xuanwei, China.
    Liu X; Zhou X; Deng CJ; Zhao Y; Shen J; Wang Y; Zhang YL
    Pathol Res Pract; 2020 Jun; 216(6):152978. PubMed ID: 32360249
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. xpo1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis.
    Zhu ZC; Liu JW; Yang C; Zhao M; Xiong ZQ
    Cell Death Dis; 2019 May; 10(6):395. PubMed ID: 31113936
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
    Fang L; Teng H; Wang Y; Liao G; Weng L; Li Y; Wang X; Jin J; Jiao C; Chen L; Peng X; Chen J; Yang Y; Fang H; Han D; Li C; Jin X; Zhang S; Liu Z; Liu M; Wei Q; Liao L; Ge X; Zhao B; Zhou D; Qin HL; Zhou J; Wang P
    Cancer Cell; 2018 Jul; 34(1):103-118.e9. PubMed ID: 30008322
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Analysis of Combined Transcriptomes Identifies Gene Modules that Differentially Respond to Pathogenic Stimulation of Vascular Smooth Muscle and Endothelial Cells.
    Pan X; Wang B; Yuan T; Zhang M; Kent KC; Guo LW
    Sci Rep; 2018 Jan; 8(1):395. PubMed ID: 29321689
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.
    Alsaran H; Elkhadragy L; Shakya A; Long W
    Sci Rep; 2017 Nov; 7(1):14979. PubMed ID: 29101390
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells.
    Liu Z; Gao W
    Toxicol Appl Pharmacol; 2017 Nov; 335():16-27. PubMed ID: 28942004
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Therapeutic Targeting of Nuclear Export Inhibition in lung cancer.
    Gupta A; Saltarski JM; White MA; Scaglioni PP; Gerber DE
    J Thorac Oncol; 2017 Sep; 12(9):1446-1450. PubMed ID: 28647672
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. xpo1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
    Kim J; McMillan E; Kim HS; Venkateswaran N; Makkar G; Rodriguez-Canales J; Villalobos P; Neggers JE; Mendiratta S; Wei S; Landesman Y; Senapedis W; Baloglu E; Chow CB; Frink RE; Gao B; Roth M; Minna JD; Daelemans D; Wistuba II; Posner BA; Scaglioni PP; White MA
    Nature; 2016 Oct; 538(7623):114-117. PubMed ID: 27680702
    [TBL] [Abstract] [Full Text] [Related]  


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