Terms: = Lymphoma AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Treatment
1115 results:
1. Novel PIKfyve/Tubulin Dual-target Inhibitor as a Promising Therapeutic Strategy for B-cell Acute Lymphoblastic Leukemia.
Lu Z; Lai Q; Li ZF; Zhong MY; Jiang YL; Feng LY; Zha J; Yao JW; Li Y; Deng XM; Xu B
Curr Med Sci; 2024 Apr; 44(2):298-308. PubMed ID: 38619682
[TBL] [Abstract] [Full Text] [Related]
2. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2
Ichikawa T; Suekane A; Nakahata S; Iha H; Shimoda K; Murakami T; Morishita K
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474089
[TBL] [Abstract] [Full Text] [Related]
3. [Effect of Chlorambucil Combined with Ibrutinib on Mantle Cell lymphoma Cell Line Jeko-1 and Its Related Mechanism].
Cai NN; Liu WY; Liu ZQ; Gong JH; Lin YL; Wang ZC; Huang YQ; Guo JX
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Feb; 32(1):132-137. PubMed ID: 38387911
[TBL] [Abstract] [Full Text] [Related]
4. A molecular circuit linking the BCR to the NAD biosynthetic enzyme NAMPT is an actionable target in Richter syndrome.
Messana VG; Fascì A; Vitale N; Micillo M; Rovere M; Pesce NA; Martines C; Efremov DG; Vaisitti T; Deaglio S
Blood Adv; 2024 Apr; 8(8):1920-1933. PubMed ID: 38359376
[TBL] [Abstract] [Full Text] [Related]
5. Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
Liang X; Yu H; Liang R; Feng Z; Saidahmatov A; Sun C; Ren H; Wei X; Zhao J; Yang C; Liu H
J Med Chem; 2024 Feb; 67(4):2884-2906. PubMed ID: 38349664
[TBL] [Abstract] [Full Text] [Related]
6. The obeticholic acid can positively regulate the cancerous behavior of MCF7 breast cancer cell line.
Rahmani R; Eivazi N; Emamgholipour S; Aminian M; Jalilian A; Paknejad M
Mol Biol Rep; 2024 Feb; 51(1):250. PubMed ID: 38302816
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7. In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/akt/mTOR pathway.
Diab SE; Tayea NA; Elwakil BH; Elshewemi SS; Gad AAEM; Abdulmalek SA; Ghareeb DA; Olama ZA
Sci Rep; 2024 Jan; 14(1):2433. PubMed ID: 38286826
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8. Transcriptomic and proteomic analysis of tumor suppressive effects of GZ17-6.02 against mycosis fungoides.
Bordeaux ZA; Reddy SV; Choi J; Braun G; McKeel J; Lu W; Yossef SM; Ma EZ; West CE; Kwatra SG; Kwatra MM
Sci Rep; 2024 Jan; 14(1):1955. PubMed ID: 38263212
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9. Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage lymphoma axis-mediated activation of the phosphoinositide 3-kinase/akt pathway.
Feng X; Yang L; Liu X; Liu M; Liu L; Liu J; Luo J
Med Oncol; 2024 Jan; 41(2):60. PubMed ID: 38252204
[TBL] [Abstract] [Full Text] [Related]
10. The CIpP activator, TR-57, is highly effective as a single agent and in combination with venetoclax against CLL cells
Fatima N; Shen Y; Crassini K; Burling O; Thurgood L; Iwanowicz EJ; Lang H; Karanewsky DS; Christopherson RI; Mulligan SP; Best OG
Leuk Lymphoma; 2024 May; 65(5):585-597. PubMed ID: 38227293
[TBL] [Abstract] [Full Text] [Related]
11. Serum Adipokines as Biomarkers for Surveillance of Metabolic Syndrome in Childhood Acute Lymphoblastic Leukemia Survivors in Low Middle-Income Countries.
Das G; Setlur K; Jana M; Ramakrishnan L; Jain V; Meena JP; Gupta AK; Dwivedi SN; Seth R
Nutr Cancer; 2024; 76(3):262-270. PubMed ID: 38225859
[TBL] [Abstract] [Full Text] [Related]
12. ATF5 promotes malignant T cell survival through the PI3K/akt/mTOR pathway in cutaneous T cell lymphoma.
Cao M; Lai P; Liu X; Liu F; Qin Y; Tu P; Wang Y
Front Immunol; 2023; 14():1282996. PubMed ID: 38223508
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13. Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age.
Seaton G; Smith H; Brancale A; Westwell AD; Clarkson R
Mol Cancer; 2024 Jan; 23(1):7. PubMed ID: 38195591
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14. E3 ubiquitin ligase casitas B-lineage lymphoma-b modulates T-cell anergic resistance via phosphoinositide 3-kinase signaling in patients with immune thrombocytopenia.
Liu L; Xiang Y; Shao L; Yuan C; Song X; Sun M; Liu Y; Zhang X; Du S; Hou M; Peng J; Shi Y
J Thromb Haemost; 2024 Apr; 22(4):1202-1214. PubMed ID: 38184203
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15. Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer.
Wu M; Xie J; Xing Y; Zhang L; Chen H; Tang B; Zhou M; Lv S; Huang D; Jian S; Zhou C; Liu M; Guo W; Chen Y; Yi Z
Int J Biol Sci; 2024; 20(2):486-501. PubMed ID: 38169532
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16. Targeting HDACs for diffuse large B-cell lymphoma therapy.
Wu C; Song Q; Gao S; Wu S
Sci Rep; 2024 Jan; 14(1):289. PubMed ID: 38168914
[TBL] [Abstract] [Full Text] [Related]
17. The gene expression profile and cell of origin of canine peripheral T-cell lymphoma.
Owens E; Harris L; Harris A; Yoshimoto J; Burnett R; Avery A
BMC Cancer; 2024 Jan; 24(1):18. PubMed ID: 38166662
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18. The role of α7-nAChR-mediated PI3K/akt pathway in lung cancer induced by nicotine.
He Z; Xu Y; Rao Z; Zhang Z; Zhou J; Zhou T; Wang H
Sci Total Environ; 2024 Feb; 912():169604. PubMed ID: 38157907
[TBL] [Abstract] [Full Text] [Related]
19. [Saikosaponin D regulates apoptosis and autophagy of pancreatic cancer Panc-1 cells via akt/mTOR pathway].
Guan YH; Liu GM; Liu YS; Lan LB; Zheng R; Liu XB
Zhongguo Zhong Yao Za Zhi; 2023 Oct; 48(19):5278-5284. PubMed ID: 38114117
[TBL] [Abstract] [Full Text] [Related]
20. Homoharringtonine induces apoptosis of mammary carcinoma cells by inhibiting the akt/mTOR signaling pathway.
Zhang X; Mei C; Liang Z; Zhi Y; Xu H; Wang H; Dong H
Vet Comp Oncol; 2024 Mar; 22(1):57-69. PubMed ID: 38081660
[TBL] [Abstract] [Full Text] [Related]
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