Terms: = Lymphoma AND BRD4, O60885, 23476, ENSG00000141867, HUNKI, CAP, MCAP AND Treatment
111 results:
1. Development of an Imidazopyridazine-Based MNK1/2 Inhibitor for the treatment of lymphoma.
Yuan X; Guan D; Chen C; Guo S; Wu H; Bu H; Yang CY; Wang M; Zhou J; Zhang H
J Med Chem; 2024 Apr; 67(7):5437-5457. PubMed ID: 38564512
[TBL] [Abstract] [Full Text] [Related]
2. Integrative analyses reveal outcome-associated and targetable molecular partnerships between TP53, brd4, TNFRSF10B, and CDKN1A in diffuse large B-cell lymphoma.
Forberg AL; Unrau J; Weber KS; Rutz AC; Lund S; Guidinger J; Pelzel A; Hauge J; Hemmen AJ; Hartert KT
Ann Hematol; 2024 Jan; 103(1):199-209. PubMed ID: 37792064
[TBL] [Abstract] [Full Text] [Related]
3. brd4 PROTAC degrader MZ1 exhibits anti-B-cell acute lymphoblastic leukemia effects via targeting CCND3.
Ma L; Wang J; Yang Y; Lu J; Ling J; Chu X; Zhang Z; Tao Y; Li X; Tian Y; Li Z; Zhang Y; Sang X; Lu L; Wan X; Zhang K; Chen Y; Yu J; Zhuo R; Wu S; Pan J; Zhou X; Hu Y; Hu S
Hematology; 2023 Dec; 28(1):2247253. PubMed ID: 37594294
[TBL] [Abstract] [Full Text] [Related]
4. Evaluation of the novel therapeutic anti-CCR7 antibody cap-100 as an add-on therapy in chronic lymphocytic leukemia patients receiving venetoclax.
Mateu-Albero T; Marcos-Jimenez A; Delgado-Wicke P; Terrón F; Loscertales J; López-Matencio JMS; Muñoz-Calleja C; Cuesta-Mateos C
Hematol Oncol; 2023 Dec; 41(5):869-876. PubMed ID: 37545392
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5. Circular RNA 0000157 depletion protects human bronchial epithelioid cells from cigarette smoke extract-induced human bronchial epithelioid cell injury through the microRNA-149-5p/bromodomain containing 4 pathway.
Song B; Wu S; Ye L; Jing Z; Cao J
Hum Exp Toxicol; 2023; 42():9603271231167581. PubMed ID: 37533154
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6. First-in-human Study of AZD5153, A Small-molecule Inhibitor of Bromodomain Protein 4, in Patients with Relapsed/Refractory Malignant Solid Tumors and lymphoma.
Hamilton EP; Wang JS; Oza AM; Patel MR; Ulahannan SV; Bauer T; Karlix JL; Zeron-Medina J; Fabbri G; Marco-Casanova P; Moorthy G; Hattersley MM; Littlewood GM; Mitchell P; Saeh J; Pouliot GP; Moore KN
Mol Cancer Ther; 2023 Oct; 22(10):1154-1165. PubMed ID: 37486983
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7. brd4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis.
Schmitt A; Grimm M; Kreienkamp N; Junge H; Labisch J; Schuhknecht L; Schönfeld C; Görsch E; Tibello A; Menck K; Bleckmann A; Lengerke C; Rosenbauer F; Grau M; Zampieri M; Schulze-Osthoff K; Klener P; Dolnikova A; Lenz G; Hailfinger S
Blood; 2023 Sep; 142(13):1143-1155. PubMed ID: 37294920
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8. Efficacy of front-line immunochemotherapy for transplant-ineligible mantle cell lymphoma: A network meta-analysis of randomized controlled trials.
Jing C; Zhao A; Wang J; Niu T
Cancer Med; 2023 Jul; 12(14):15107-15116. PubMed ID: 37264757
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9. BET inhibition targets ABC-DLBCL constitutive B-cell receptor signaling through PAX5.
Oien DB; Sharma S; Hattersley MM; DuPont M; Criscione SW; Prickett L; Goeppert AU; Drew L; Yao Y; Zhang J; Chan HM
Blood Adv; 2023 Sep; 7(17):5108-5121. PubMed ID: 37184294
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10. Superiority of ibrutinib plus bendamustine and rituximab in newly diagnosed patients with mantle-cell lymphoma ineligible for intensive therapy: A network meta-analysis.
Sheng Z; Wang L
Eur J Haematol; 2023 Jun; 110(6):602-607. PubMed ID: 36919283
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11. Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's lymphomas and Diffuse Large B-cell lymphoma.
Hamlin PA; Musteata V; Park SI; Burnett C; Dabovic K; Strack T; Williams ET; Anand BS; Higgins JP; Persky DO
Cancer Res Commun; 2022 May; 2(5):307-315. PubMed ID: 36875713
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12. Oncolytic strategy using new bifunctional HDACs/brd4 inhibitors against virus-associated lymphomas.
Chen J; Wang Z; Phuc T; Xu Z; Yang D; Chen Z; Lin Z; Kendrick S; Dai L; Li HY; Qin Z
PLoS Pathog; 2023 Jan; 19(1):e1011089. PubMed ID: 36638143
[TBL] [Abstract] [Full Text] [Related]
13. The CDK4/6-UCHL5-brd4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing brd4 protein degradation.
Amari K; Sasagawa S; Imayoshi N; Toda Y; Hosogi S; Imamura T; Ashihara E
Biochem Biophys Res Commun; 2022 Jan; 588():147-153. PubMed ID: 34954522
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14. Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies.
Szydłowski M; Garbicz F; Jabłońska E; Górniak P; Komar D; Pyrzyńska B; Bojarczuk K; Prochorec-Sobieszek M; Szumera-Ciećkiewicz A; Rymkiewicz G; Cybulska M; Statkiewicz M; Gajewska M; Mikula M; Gołas A; Domagała J; Winiarska M; Graczyk-Jarzynka A; Białopiotrowicz E; Polak A; Barankiewicz J; Puła B; Pawlak M; Nowis D; Golab J; Tomirotti AM; Brzózka K; Pacheco-Blanco M; Kupcova K; Green MR; Havranek O; Chapuy B; Juszczyński P
Cancer Res; 2021 Dec; 81(23):6029-6043. PubMed ID: 34625423
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15. Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2.
Mill CP; Fiskus W; DiNardo CD; Birdwell C; Davis JA; Kadia TM; Takahashi K; Short N; Daver N; Ohanian M; Borthakur G; Kornblau SM; Green MR; Qi Y; Su X; Khoury JD; Bhalla KN
Blood; 2022 Feb; 139(6):907-921. PubMed ID: 34601571
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16. capecitabine Can Induce T Cell Apoptosis: A Potential Immunosuppressive Agent With Anti-Cancer Effect.
Zhang S; Wang Z; Fan S; Liu T; Yoshida S; Yang S; Liu L; Hou W; Cao L; Wang J; Song Z; Li S; Zhang S; Wang H; Li J; Zheng H; Shen Z
Front Immunol; 2021; 12():737849. PubMed ID: 34557199
[TBL] [Abstract] [Full Text] [Related]
17. Influences of cold atmospheric plasma on apoptosis related molecules in osteoblast-like cells in vitro.
Eggers B; Marciniak J; Memmert S; Wagner G; Deschner J; Kramer FJ; Nokhbehsaim M
Head Face Med; 2021 Sep; 17(1):37. PubMed ID: 34479596
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18. Role of Dot1L and H3K79 methylation in regulating somatic hypermutation of immunoglobulin genes.
Duan Z; Baughn LB; Wang X; Zhang Y; Gupta V; MacCarthy T; Scharff MD; Yu G
Proc Natl Acad Sci U S A; 2021 Jul; 118(29):. PubMed ID: 34253616
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19. Bromodomain-containing protein 4 inhibitor JQ1 promotes melanoma cell apoptosis by regulating mitochondrial dynamics.
Li L; Meng Y; Wu X; Li J; Sun Y
Cancer Sci; 2021 Oct; 112(10):4013-4025. PubMed ID: 34252226
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20. A modified endoscopic full thickness resection for gastric subepithelial tumors from muscularis propria layer: Novel method.
Lee JM; Yoo IK; Hong SP; Cho JY; Cho YK
J Gastroenterol Hepatol; 2021 Sep; 36(9):2558-2561. PubMed ID: 33755260
[TBL] [Abstract] [Full Text] [Related]
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