BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lymphoma AND HOXA9, HOX1, 3205, ENSG00000078399, HOX1G, P31269 AND Treatment
18 results:

  • 1. MEIS inhibitors reduce the viability of primary leukemia cells and Stem cells by inducing apoptosis.
    Meriç N; Albayrak E; Gülbaş Z; Kocabaş F
    Leuk Lymphoma; 2024 Feb; 65(2):187-198. PubMed ID: 37902585
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Panobinostat (LBH589) increase survival in adult xenografic model of acute lymphoblastic leukemia with t(4;11) but promotes antagonistic effects in combination with MTX and 6MP.
    Moreno DA; Junior HLR; Laranjeira ABA; Cruzeiro GAV; Borges KS; Salomão KB; Ramalho FS; Yunes JA; Silva CLA; Rego EM; Scrideli CA; Tone LG
    Med Oncol; 2022 Sep; 39(12):216. PubMed ID: 36175721
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RNA-binding proteins as drivers of AML and novel therapeutic targets.
    Qin T; Cheng Y; Wang X
    Leuk Lymphoma; 2022 May; 63(5):1045-1057. PubMed ID: 35075986
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup.
    Touzart A; Mayakonda A; Smith C; Hey J; Toth R; Cieslak A; Andrieu GP; Tran Quang C; Latiri M; Ghysdael J; Spicuglia S; Dombret H; Ifrah N; Macintyre E; Lutsik P; Boissel N; Plass C; Asnafi V
    Sci Transl Med; 2021 May; 13(595):. PubMed ID: 34039737
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. hoxa9/IRX1 expression pattern defines two subgroups of infant MLL-AF4-driven acute lymphoblastic leukemia.
    Symeonidou V; Ottersbach K
    Exp Hematol; 2021 Jan; 93():38-43.e5. PubMed ID: 33069783
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.
    Lim JT; Singh N; Leuvano LA; Calvert VS; Petricoin EF; Teachey DT; Lock RB; Padi M; Kraft AS; Padi SKR
    Mol Cancer Ther; 2020 Sep; 19(9):1809-1821. PubMed ID: 32753387
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4
    Bardini M; Trentin L; Rizzo F; Vieri M; Savino AM; Garrido Castro P; Fazio G; Van Roon EHJ; Kerstjens M; Smithers N; Prinjha RK; Te Kronnie G; Basso G; Stam RW; Pieters R; Biondi A; Cazzaniga G
    Mol Cancer Ther; 2018 Aug; 17(8):1705-1716. PubMed ID: 29748211
    [No Abstract]    [Full Text] [Related]  

  • 8. CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.
    Somers K; Chudakova DA; Middlemiss SM; Wen VW; Clifton M; Kwek A; Liu B; Mayoh C; Bongers A; Karsa M; Pan S; Cruikshank S; Scandlyn M; Hoang W; Imamura T; Kees UR; Gudkov AV; Chernova OB; Haber M; Norris MD; Henderson MJ
    Oncotarget; 2016 Jul; 7(29):46067-46087. PubMed ID: 27317766
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Expression of homeobox gene hoxa9 in childhood acute leukemia, and its clinical significance].
    Jia XH; Zhu LP; Li JC; Wang CC
    Zhongguo Dang Dai Er Ke Za Zhi; 2013 Apr; 15(4):268-72. PubMed ID: 23607948
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Regulation of the MIR155 host gene in physiological and pathological processes.
    Elton TS; Selemon H; Elton SM; Parinandi NL
    Gene; 2013 Dec; 532(1):1-12. PubMed ID: 23246696
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia.
    Ye H; Liu X; Lv M; Wu Y; Kuang S; Gong J; Yuan P; Zhong Z; Li Q; Jia H; Sun J; Chen Z; Guo AY
    Nucleic Acids Res; 2012 Jul; 40(12):5201-14. PubMed ID: 22362744
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice.
    Tamai H; Miyake K; Yamaguchi H; Takatori M; Dan K; Inokuchi K; Shimada T
    Blood; 2012 Jan; 119(1):64-71. PubMed ID: 22025528
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Polycomb repressor complex 2 regulates hoxa9 and HOXA10, activating ID2 in NK/T-cell lines.
    Nagel S; Venturini L; Marquez VE; Meyer C; Kaufmann M; Scherr M; MacLeod RA; Drexler HG
    Mol Cancer; 2010 Jun; 9():151. PubMed ID: 20565746
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
    Lin YW; Beharry ZM; Hill EG; Song JH; Wang W; Xia Z; Zhang Z; Aplan PD; Aster JC; Smith CD; Kraft AS
    Blood; 2010 Jan; 115(4):824-33. PubMed ID: 19965690
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Two consecutive immunophenotypic switches in a child with MLL-rearranged acute lymphoblastic leukemia.
    Germano G; Pigazzi M; del Giudice L; Campo Dell'Orto M; Spinelli M; Zangrando A; Paolucci P; Ladogana S; Basso G
    Haematologica; 2006 May; 91(5 Suppl):ECR09. PubMed ID: 16709517
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. In vivo drug-response in patients with leukemic non-Hodgkin's lymphomas is associated with in vitro chemosensitivity and gene expression profiling.
    Chow KU; Nowak D; Kim SZ; Schneider B; Komor M; Boehrer S; Mitrou PS; Hoelzer D; Weidmann E; Hofmann WK
    Pharmacol Res; 2006 Jan; 53(1):49-61. PubMed ID: 16213748
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Upregulated hoxC4 induces CD14 expression during the differentiation of acute promyelocytic leukemia cells.
    Kim DY; Choi SJ; Kim SH; Chung HY; Yi S; Kim DW; Kim CC; Han TH
    Leuk Lymphoma; 2005 Jul; 46(7):1061-6. PubMed ID: 16019559
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Estrogen-regulated conditional oncoproteins: tools to address open questions in normal myeloid cell function, normal myeloid differentiation, and the genetic basis of differentiation arrest in myeloid leukemia.
    Sykes DB; Kamps MP
    Leuk Lymphoma; 2003 Jul; 44(7):1131-9. PubMed ID: 12916864
    [TBL] [Abstract] [Full Text] [Related]  


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