BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lymphoma AND JAK3, L-JAK, 3718, ENSG00000105639, P52333, JAKL, JAK-3, LJAK, JAK3_HUMAN AND Treatment
59 results:

  • 1. treatment patterns, clinical outcomes and gene mutation characteristics of hepatitis B virus-associated mantle cell lymphoma.
    Feng J; Fei Y; Gao M; Meng X; Zeng D; Zou D; Ye H; Liang Y; Sun X; Liang R; Zhou H; Wang X; Zhang H
    Hematol Oncol; 2024 May; 42(3):e3268. PubMed ID: 38676394
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. N-Acetylcysteine Alters Disease Progression and Increases Janus Kinase Mutation Frequency in a Mouse Model of Precursor B-Cell Acute Lymphoblastic Leukemia.
    Sams MP; Iansavitchous J; Astridge M; Rysan H; Xu LS; Rodrigues de Oliveira B; DeKoter RP
    J Pharmacol Exp Ther; 2024 Mar; 389(1):40-50. PubMed ID: 38336380
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. A Workflow Combining Machine Learning with Molecular Simulations Uncovers Potential Dual-Target Inhibitors against BTK and jak3.
    Liu L; Na R; Yang L; Liu J; Tan Y; Zhao X; Huang X; Chen X
    Molecules; 2023 Oct; 28(20):. PubMed ID: 37894618
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Dependence of peripheral T-cell lymphoma on constitutively activated jak3: Implication for jak3 inhibition as a therapeutic approach.
    Le K; Vollenweider J; Han J; Staudinger N; Stenson M; Bayraktar L; Wellik LE; Maurer MJ; McPhail ED; Witzig TE; Gupta M
    Hematol Oncol; 2024 Jan; 42(1):e3233. PubMed ID: 37876297
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The jak3
    Lahera A; Vela-Martín L; Fernández-Navarro P; Llamas P; López-Lorenzo JL; Cornago J; Santos J; Fernández-Piqueras J; Villa-Morales M
    Mol Carcinog; 2024 Jan; 63(1):5-10. PubMed ID: 37712558
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Characteristics of Molecular Genetic Mutations and Their Correlation with Prognosis in Adolescent and Adult Patients with Acute Lymphoblastic Leukemia.
    Sun X; Liu X; Li Y; Shi X; Li Y; Tan R; Jiang Y; Sui X; Ge X; Xu H; Wang X; Fang X
    Oncology; 2024; 102(1):85-98. PubMed ID: 37437551
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Mutational profiling of circulating tumor DNA and clinical characteristics in lymphoma: Based on next generation sequencing.
    Hou Y; Zi J; Liu S; Ge Q; Ge Z
    Mol Carcinog; 2023 Feb; 62(2):200-209. PubMed ID: 36300887
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. IL-7: Comprehensive review.
    Winer H; Rodrigues GOL; Hixon JA; Aiello FB; Hsu TC; Wachter BT; Li W; Durum SK
    Cytokine; 2022 Dec; 160():156049. PubMed ID: 36201890
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Janus kinase (JAK) inhibitors in the treatment of neoplastic and inflammatory disorders.
    Roskoski R
    Pharmacol Res; 2022 Sep; 183():106362. PubMed ID: 35878738
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. jak3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia.
    Bodaar K; Yamagata N; Barthe A; Landrigan J; Chonghaile TN; Burns M; Stevenson KE; Devidas M; Loh ML; Hunger SP; Wood B; Silverman LB; Teachey DT; Meijerink JP; Letai A; Gutierrez A
    Leukemia; 2022 Jun; 36(6):1499-1507. PubMed ID: 35411095
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of cyano-substituted 2,4-diarylaminopyrimidines as potent jak3 inhibitors for the treatment of B-cell lymphoma.
    Wu B; Yang S; Deng T; Wang C; Jin Y; Yu J; Xu Y; Chen L; Li Y; Ma X
    Bioorg Chem; 2021 Nov; 116():105330. PubMed ID: 34547646
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. PHF6 and jak3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.
    Yuan S; Wang X; Hou S; Guo T; Lan Y; Yang S; Zhao F; Gao J; Wang Y; Chu Y; Shi J; Cheng T; Yuan W
    Leukemia; 2022 Feb; 36(2):370-382. PubMed ID: 34465864
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Mutant
    Goldberg L; Negi V; Chung YJ; Onozawa M; Zhu YJ; Walker RL; Pierce R; Patel DP; Krausz KW; Gonzalez FJ; Goodell MA; Rodriguez BAT; Meltzer PS; Aplan PD
    Cancer Res; 2021 Oct; 81(19):5033-5046. PubMed ID: 34321240
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. How much has allogeneic stem cell transplant-related mortality improved since the 1980s? A retrospective analysis from the EBMT.
    Penack O; Peczynski C; Mohty M; Yakoub-Agha I; Styczynski J; Montoto S; Duarte RF; Kröger N; Schoemans H; Koenecke C; Peric Z; Basak GW
    Blood Adv; 2020 Dec; 4(24):6283-6290. PubMed ID: 33351121
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Failure of tofacitinib to achieve an objective response in a
    Wong J; Wall M; Corboy GP; Taubenheim N; Gregory GP; Opat S; Shortt J
    Cold Spring Harb Mol Case Stud; 2020 Aug; 6(4):. PubMed ID: 32843425
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. jak3 inhibitors based on thieno[3,2-d]pyrimidine scaffold: design, synthesis and bioactivity evaluation for the treatment of B-cell lymphoma.
    Chi F; Chen L; Wang C; Li L; Sun X; Xu Y; Ma T; Liu K; Ma X; Shu X
    Bioorg Chem; 2020 Jan; 95():103542. PubMed ID: 31918398
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The clinical mutatome of core binding factor leukemia.
    Opatz S; Bamopoulos SA; Metzeler KH; Herold T; Ksienzyk B; Bräundl K; Tschuri S; Vosberg S; Konstandin NP; Wang C; Hartmann L; Graf A; Krebs S; Blum H; Schneider S; Thiede C; Middeke JM; Stölzel F; Röllig C; Schetelig J; Ehninger G; Krämer A; Braess J; Görlich D; Sauerland MC; Berdel WE; Wörmann BJ; Hiddemann W; Spiekermann K; Bohlander SK; Greif PA
    Leukemia; 2020 Jun; 34(6):1553-1562. PubMed ID: 31896782
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Genome profiling revealed the activation of IL2RG/jak3/STAT5 in peripheral T‑cell lymphoma expressing the ITK‑SYK fusion gene.
    Zhang LL; Pan HX; Wang YX; Guo T; Liu L
    Int J Oncol; 2019 Nov; 55(5):1077-1089. PubMed ID: 31545408
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Advanced-stage mycosis fungoides: role of the signal transducer and activator of transcription 3, nuclear factor-κB and nuclear factor of activated T cells pathways.
    Pérez C; Mondéjar R; García-Díaz N; Cereceda L; León A; Montes S; Durán Vian C; Pérez Paredes MG; González-Morán A; Alegre de Miguel V; Sanz Anquela JM; Frias J; Limeres MA; González LM; Martín Dávila F; Beltrán M; Mollejo M; Méndez JR; González MA; González García J; López R; Gómez A; Izquierdo F; Ramos R; Camacho C; Rodriguez-Pinilla SM; Martínez N; Vaqué JP; Ortiz-Romero PL; Piris MA
    Br J Dermatol; 2020 Jan; 182(1):147-155. PubMed ID: 31049933
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. jak3/STAT3 oncogenic pathway and PRDM1 expression stratify clinicopathologic features of extranodal NK/T‑cell lymphoma, nasal type.
    Liu J; Liang L; Li D; Nong L; Zheng Y; Huang S; Zhang B; Li T
    Oncol Rep; 2019 Jun; 41(6):3219-3232. PubMed ID: 31002364
    [TBL] [Abstract] [Full Text] [Related]  


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