BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lymphoma AND LCK, YT16, 3932, P06239, ENSG00000182866, p56lck, pp58lck AND Prognosis
8 results:

  • 1. Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
    Jin Q; Gutierrez Diaz B; Pieters T; Zhou Y; Narang S; Fijalkwoski I; Borin C; Van Laere J; Payton M; Cho BK; Han C; Sun L; Serafin V; Yacu G; Von Loocke W; Basso G; Veltri G; Dreveny I; Ben-Sahra I; Goo YA; Safgren SL; Tsai YC; Bornhauser B; Suraneni PK; Gaspar-Maia A; Kandela I; Van Vlierberghe P; Crispino JD; Tsirigos A; Ntziachristos P
    Sci Adv; 2022 Dec; 8(49):eabq8437. PubMed ID: 36490346
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120.
    Fazio G; Bresolin S; Silvestri D; Quadri M; Saitta C; Vendramini E; Buldini B; Palmi C; Bardini M; Grioni A; Rigamonti S; Galbiati M; Mecca S; Savino AM; Peloso A; Tu JW; Bhatia S; Borkhardt A; Micalizzi C; Lo Nigro L; Locatelli F; Conter V; Rizzari C; Valsecchi MG; Te Kronnie G; Biondi A; Cazzaniga G
    EBioMedicine; 2022 Sep; 83():104224. PubMed ID: 35985167
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Therapeutic targeting of lck tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.
    Laukkanen S; Veloso A; Yan C; Oksa L; Alpert EJ; Do D; Hyvärinen N; McCarthy K; Adhikari A; Yang Q; Iyer S; Garcia SP; Pello A; Ruokoranta T; Moisio S; Adhikari S; Yoder JA; Gallagher K; Whelton L; Allen JR; Jin AH; Loontiens S; Heinäniemi M; Kelliher M; Heckman CA; Lohi O; Langenau DM
    Blood; 2022 Oct; 140(17):1891-1906. PubMed ID: 35544598
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Dasatinib-therapy induced sustained remission in a child with refractory TCF7-SPI1 T-cell acute lymphoblastic leukemia.
    He Y; Zhang J; Zhang Y; Hu Z; Wang P; Gan W; Xie S; Qian M; Pui CH; Jiang H; Zhu X; Zhang H; Zhang W
    Pediatr Blood Cancer; 2022 Aug; 69(8):e29724. PubMed ID: 35441457
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-lck hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified.
    Debackere K; Marcelis L; Demeyer S; Vanden Bempt M; Mentens N; Gielen O; Jacobs K; Broux M; Verhoef G; Michaux L; Graux C; Wlodarska I; Gaulard P; de Leval L; Tousseyn T; Cools J; Dierickx D
    Nat Commun; 2021 Jun; 12(1):3705. PubMed ID: 34140493
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. lck expression is a potential biomarker for distinguishing primary central nervous system lymphoma from glioblastoma multiforme.
    Ge L; Xu L; Lu S; Yan H
    FEBS Open Bio; 2020 May; 10(5):904-911. PubMed ID: 32237064
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
    Spijkers-Hagelstein JA; Mimoso Pinhanços S; Schneider P; Pieters R; Stam RW
    Leukemia; 2013 Apr; 27(5):1063-71. PubMed ID: 23334362
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Dasatinib.
    Lindauer M; Hochhaus A
    Recent Results Cancer Res; 2010; 184():83-102. PubMed ID: 20072833
    [TBL] [Abstract] [Full Text] [Related]  


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