BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lymphoma AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602
21 results:

  • 1. A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
    Zhang Z; Hao C; Zhang R; Pei X; Li J; Wang L
    Cell Cycle; 2020 Aug; 19(16):2063-2073. PubMed ID: 32677544
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Targeting the cross-talk between the hedgehog and NF-κB signaling pathways in multiple myeloma.
    Cai K; Na W; Guo M; Xu R; Wang X; Qin Y; Wu Y; Jiang J; Huang H
    Leuk Lymphoma; 2019 Mar; 60(3):772-781. PubMed ID: 30644322
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia.
    Burns MA; Liao ZW; Yamagata N; Pouliot GP; Stevenson KE; Neuberg DS; Thorner AR; Ducar M; Silverman EA; Hunger SP; Loh ML; Winter SS; Dunsmore KP; Wood B; Devidas M; Harris MH; Silverman LB; Sallan SE; Gutierrez A
    Leukemia; 2018 Oct; 32(10):2126-2137. PubMed ID: 29654263
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.
    Chaudhary SC; Tang X; Arumugam A; Li C; Srivastava RK; Weng Z; Xu J; Zhang X; Kim AL; McKay K; Elmets CA; Kopelovich L; Bickers DR; Athar M
    Oncotarget; 2015 Nov; 6(34):36789-814. PubMed ID: 26413810
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma.
    Cookman CJ; Belcher SM
    Endocrinology; 2015 Jul; 156(7):2395-408. PubMed ID: 25885794
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Primary cutaneous follicle center lymphoma with diffuse CD30 expression: a report of 4 cases of a rare variant.
    Kempf W; Kazakov DV; Rütten A; Rupec RA; Talarcik P; Ballová V; Kerl K; Dummer R; Lautenschlager S; Zimmermann DR; Tinguely M
    J Am Acad Dermatol; 2014 Sep; 71(3):548-54. PubMed ID: 24836545
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Multiple tumor types including leiomyoma and Wilms tumor in a patient with Gorlin syndrome due to 9q22.3 microdeletion encompassing the ptch1 and FANC-C loci.
    Garavelli L; Piemontese MR; Cavazza A; Rosato S; Wischmeijer A; Gelmini C; Albertini E; Albertini G; Forzano F; Franchi F; Carella M; Zelante L; Superti-Furga A
    Am J Med Genet A; 2013 Nov; 161A(11):2894-901. PubMed ID: 24124115
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Clinical benefit from pemetrexed before and after crizotinib exposure and from crizotinib before and after pemetrexed exposure in patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer.
    Berge EM; Lu X; Maxson D; Barón AE; Gadgeel SM; Solomon BJ; Doebele RC; Varella-Garcia M; Camidge DR
    Clin Lung Cancer; 2013 Nov; 14(6):636-43. PubMed ID: 23931899
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Noncanonical regulation of the Hedgehog mediator GLI1 by c-MYC in Burkitt lymphoma.
    Yoon JW; Gallant M; Lamm ML; Iannaccone S; Vieux KF; Proytcheva M; Hyjek E; Iannaccone P; Walterhouse D
    Mol Cancer Res; 2013 Jun; 11(6):604-15. PubMed ID: 23525267
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status.
    Cea M; Cagnetta A; Cirmena G; Garuti A; Rocco I; Palermo C; Pierri I; Reverberi D; Nencioni A; Ballestrero A; Gobbi M; Carella AM; Patrone F
    Leuk Lymphoma; 2013 Feb; 54(2):342-52. PubMed ID: 22762548
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro.
    Wu JY; Xu XF; Xu L; Niu PQ; Wang F; Hu GY; Wang XP; Guo CY
    Hepatogastroenterology; 2011; 58(110-111):1511-8. PubMed ID: 21940310
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Xeroderma pigmentosum skin: an immune privilege site for tumor development.
    Abid K; El Mezni F; Kamoun MR; Fazaa B; Zermani R; Hadouchi C; Hamzaoui K
    J Cutan Pathol; 2010 Apr; 37(4):452-9. PubMed ID: 19719835
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma.
    Hegde GV; Munger CM; Emanuel K; Joshi AD; Greiner TC; Weisenburger DD; Vose JM; Joshi SS
    Mol Cancer Ther; 2008 Jun; 7(6):1450-60. PubMed ID: 18524848
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. [The effect of Chernobyl accident on the development of malignant diseases--situation after 20 years].
    Zonenberg A; Zarzycki W; Leoniak M
    Endokrynol Pol; 2006; 57(3):244-52. PubMed ID: 16832789
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. MTHFR C677 T gene polymorphism in lymphoproliferative diseases.
    Deligezer U; Akisik EE; Yaman F; Erten N; Dalay N
    J Clin Lab Anal; 2006; 20(2):37-41. PubMed ID: 16538645
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures.
    Mahadevan D; Spier C; Della Croce K; Miller S; George B; Riley C; Warner S; Grogan TM; Miller TP
    Mol Cancer Ther; 2005 Dec; 4(12):1867-79. PubMed ID: 16373702
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Multiple synchronous pigmented basal cell carcinomas following radiotherapy for Hodgkin's disease.
    Stante M; Salvini C; De Giorgi V; Carli P
    Int J Dermatol; 2002 Apr; 41(4):208-11. PubMed ID: 12031028
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Loss of p53 promotes anaplasia and local invasion in ret/ptc1-induced thyroid carcinomas.
    La Perle KM; Jhiang SM; Capen CC
    Am J Pathol; 2000 Aug; 157(2):671-7. PubMed ID: 10934169
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Nevoid basal cell carcinoma syndrome and non-Hodgkin's lymphoma.
    Schulz-Butulis BA; Gilson R; Farley M; Keeling JH
    Cutis; 2000 Jul; 66(1):35-8. PubMed ID: 10916689
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: extended follow up.
    Blair A; Hartge P; Stewart PA; McAdams M; Lubin J
    Occup Environ Med; 1998 Mar; 55(3):161-71. PubMed ID: 9624267
    [TBL] [Abstract] [Full Text] [Related]  


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