Terms: = Lymphoma AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
29 results:
1. Circular RNA hsa_circ_0004381 Promotes Neuronal Injury in Parkinson's Disease Cell Model by miR-185-5p/rac1 Axis.
Zhang H; Wang C; Zhang X
Neurotox Res; 2022 Aug; 40(4):1007-1019. PubMed ID: 35726081
[TBL] [Abstract] [Full Text] [Related]
2. TIAM1-rac1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change.
Payapilly A; Guilbert R; Descamps T; White G; Magee P; Zhou C; Kerr A; Simpson KL; Blackhall F; Dive C; Malliri A
Cell Rep; 2021 Nov; 37(6):109979. PubMed ID: 34758330
[TBL] [Abstract] [Full Text] [Related]
3. Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism.
Chang JG; Tien N; Chang YC; Lin ML; Chen SS
Cells; 2021 May; 10(6):. PubMed ID: 34064109
[TBL] [Abstract] [Full Text] [Related]
4. Mechanisms and consequences of dysregulation of the Tiam family of Rac activators in disease.
Maltas J; Reed H; Porter A; Malliri A
Biochem Soc Trans; 2020 Dec; 48(6):2703-2719. PubMed ID: 33200195
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5. Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting.
Karvonen H; Perttilä R; Niininen W; Hautanen V; Barker H; Murumägi A; Heckman CA; Ungureanu D
Oncogene; 2019 Apr; 38(17):3288-3300. PubMed ID: 30631148
[TBL] [Abstract] [Full Text] [Related]
6. Tiam1 promotes thyroid carcinoma metastasis by modulating EMT via Wnt/β-catenin signaling.
Liu L; Wu B; Cai H; Li D; Ma Y; Zhu X; Lv Z; Fan Y; Zhang X
Exp Cell Res; 2018 Jan; 362(2):532-540. PubMed ID: 29277502
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7. Type II cGMP‑dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells.
Wu M; Wu Y; Qian H; Tao Y; Pang J; Wang Y; Chen Y
Mol Med Rep; 2017 Oct; 16(4):5729-5737. PubMed ID: 28849123
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8. Tiam1/rac1 complex controls Il17a transcription and autoimmunity.
Kurdi AT; Bassil R; Olah M; Wu C; Xiao S; Taga M; Frangieh M; Buttrick T; Orent W; Bradshaw EM; Khoury SJ; Elyaman W
Nat Commun; 2016 Oct; 7():13048. PubMed ID: 27725632
[TBL] [Abstract] [Full Text] [Related]
9. Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Zhu Y; Tao M; Wu J; Meng Y; Xu C; Tian Y; Zhou X; Xiang J; Zhang H; Xie Y
Cancer Gene Ther; 2016 Apr; 23(4):98-106. PubMed ID: 26987289
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10. Inhibition of Endometrial Tiam1/rac1 Signals Induced by miR-22 Up-Regulation Leads to the Failure of Embryo Implantation During the Implantation Window in Pregnant Mice.
Ma HL; Gong F; Tang Y; Li X; Li X; Yang X; Lu G
Biol Reprod; 2015 Jun; 92(6):152. PubMed ID: 25926441
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11. Upregulated TRIO expression correlates with a malignant phenotype in human hepatocellular carcinoma.
Wang B; Fang J; Qu L; Cao Z; Zhou J; Deng B
Tumour Biol; 2015 Sep; 36(9):6901-8. PubMed ID: 25851347
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12. Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap-/- mice.
Hsieh WC; Chuang YT; Chiang IH; Hsu SC; Miaw SC; Lai MZ
Blood; 2014 Oct; 124(18):2847-57. PubMed ID: 25190756
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13. Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia.
DeAngelo DJ; Stevenson KE; Dahlberg SE; Silverman LB; Couban S; Supko JG; Amrein PC; Ballen KK; Seftel MD; Turner AR; Leber B; Howson-Jan K; Kelly K; Cohen S; Matthews JH; Savoie L; Wadleigh M; Sirulnik LA; Galinsky I; Neuberg DS; Sallan SE; Stone RM
Leukemia; 2015 Mar; 29(3):526-34. PubMed ID: 25079173
[TBL] [Abstract] [Full Text] [Related]
14. DNA damage induces the accumulation of Tiam1 by blocking β-TrCP-dependent degradation.
Zhu G; Fan Z; Ding M; Mu L; Liang J; Ding Y; Fu Y; Huang B; Wu W
J Biol Chem; 2014 May; 289(22):15482-94. PubMed ID: 24737324
[TBL] [Abstract] [Full Text] [Related]
15. Tiam1/rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.
Hofbauer SW; Krenn PW; Ganghammer S; Asslaber D; Pichler U; Oberascher K; Henschler R; Wallner M; Kerschbaum H; Greil R; Hartmann TN
Blood; 2014 Apr; 123(14):2181-8. PubMed ID: 24501217
[TBL] [Abstract] [Full Text] [Related]
16. 5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and rac1 activation.
Magi S; Takemoto Y; Kobayashi H; Kasamatsu M; Akita T; Tanaka A; Takano K; Tashiro E; Igarashi Y; Imoto M
Cancer Sci; 2014 Mar; 105(3):290-6. PubMed ID: 24350867
[TBL] [Abstract] [Full Text] [Related]
17. STAT3 mediates oncogenic addiction to TEL-AML1 in t(12;21) acute lymphoblastic leukemia.
Mangolini M; de Boer J; Walf-Vorderwülbecke V; Pieters R; den Boer ML; Williams O
Blood; 2013 Jul; 122(4):542-9. PubMed ID: 23741012
[TBL] [Abstract] [Full Text] [Related]
18. Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and rac1 GTPases.
Zhu Y; Casey PJ; Kumar AP; Pervaiz S
Cell Death Dis; 2013 Apr; 4(4):e568. PubMed ID: 23559002
[TBL] [Abstract] [Full Text] [Related]
19. Prostaglandin D2-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/rac1 pathway.
Kobayashi K; Tsubosaka Y; Hori M; Narumiya S; Ozaki H; Murata T
Arterioscler Thromb Vasc Biol; 2013 Mar; 33(3):565-71. PubMed ID: 23307871
[TBL] [Abstract] [Full Text] [Related]
20. Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b.
Infante E; Heasman SJ; Ridley AJ
J Leukoc Biol; 2011 Apr; 89(4):577-86. PubMed ID: 21233409
[TBL] [Abstract] [Full Text] [Related]
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