Terms: = Lymphoma AND SUZ12, CHET9, 23512, ENSG00000178691, Q15022, KIAA0160, JJAZ1
37 results:
1. EZH2 K63-polyubiquitination affecting migration in extranodal natural killer/T-cell lymphoma.
Li B; Zhou Q; Wan Q; Qiao X; Chen S; Zhou J; Wuxiao Z; Luo L; Ng SB; Li J; Chng WJ
Clin Epigenetics; 2023 Nov; 15(1):187. PubMed ID: 38031139
[TBL] [Abstract] [Full Text] [Related]
2. Design, synthesis and evaluation of EZH2-based PROTACs targeting PRC2 complex in lymphoma.
Xie H; Xu W; Liang J; Liu Y; Zhuo C; Zou X; Luo W; Xiao J; Lin Y; Chen L; Li H
Bioorg Chem; 2023 Nov; 140():106762. PubMed ID: 37572533
[TBL] [Abstract] [Full Text] [Related]
3. PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components.
Bashore FM; Foley CA; Ong HW; Rectenwald JM; Hanley RP; Norris-Drouin JL; Cholensky SH; Mills CA; Pearce KH; Herring LE; Kireev D; Frye SV; James LI
ACS Chem Biol; 2023 Mar; 18(3):494-507. PubMed ID: 36877831
[TBL] [Abstract] [Full Text] [Related]
4. Prognostic utility of key copy number alterations in T cell acute lymphoblastic leukemia.
Kumari S; Ali MS; Singh J; Arora M; Verma D; Pandey AK; Benjamin M; Bakhshi S; Palanichamy JK; Sharma A; Singh I; Tanwar P; Singh AR; Pushpam D; Qamar I; Chopra A
Hematol Oncol; 2022 Oct; 40(4):577-587. PubMed ID: 35644022
[TBL] [Abstract] [Full Text] [Related]
5. EZH2 expression is associated with inferior overall survival in mantle cell lymphoma.
Martinez-Baquero D; Sakhdari A; Mo H; Kim DH; Kanagal-Shamanna R; Li S; Young KH; O'Malley DP; Dogan A; Jain P; Wang ML; McDonnell TJ; Miranda RN; Vega F; Medeiros LJ; Ok CY
Mod Pathol; 2021 Dec; 34(12):2183-2191. PubMed ID: 34376807
[TBL] [Abstract] [Full Text] [Related]
6. Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies.
Kaito S; Iwama A
Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33374737
[TBL] [Abstract] [Full Text] [Related]
7. Small Molecule Approaches for Targeting the Polycomb Repressive Complex 2 (PRC2) in Cancer.
Martin MC; Zeng G; Yu J; Schiltz GE
J Med Chem; 2020 Dec; 63(24):15344-15370. PubMed ID: 33283516
[TBL] [Abstract] [Full Text] [Related]
8. Stochastic Epigenetic Mutations Are Associated with Risk of Breast Cancer, Lung Cancer, and Mature B-cell Neoplasms.
Gagliardi A; Dugué PA; Nøst TH; Southey MC; Buchanan DD; Schmidt DF; Makalic E; Hodge AM; English DR; Doo NW; Hopper JL; Severi G; Baglietto L; Naccarati A; Tarallo S; Pace L; Krogh V; Palli D; Panico S; Sacerdote C; Tumino R; Lund E; Giles GG; Pardini B; Sandanger TM; Milne RL; Vineis P; Polidoro S; Fiorito G
Cancer Epidemiol Biomarkers Prev; 2020 Oct; 29(10):2026-2037. PubMed ID: 32788174
[TBL] [Abstract] [Full Text] [Related]
9. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader.
Potjewyd F; Turner AW; Beri J; Rectenwald JM; Norris-Drouin JL; Cholensky SH; Margolis DM; Pearce KH; Herring LE; James LI
Cell Chem Biol; 2020 Jan; 27(1):47-56.e15. PubMed ID: 31831267
[TBL] [Abstract] [Full Text] [Related]
10. Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations.
Zhu K; Du D; Yang R; Tao H; Zhang H
Chem Pharm Bull (Tokyo); 2020 Jan; 68(1):58-63. PubMed ID: 31685780
[TBL] [Abstract] [Full Text] [Related]
11. suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.
Broux M; Prieto C; Demeyer S; Vanden Bempt M; Alberti-Servera L; Lodewijckx I; Vandepoel R; Mentens N; Gielen O; Jacobs K; Geerdens E; Vicente C; de Bock CE; Cools J
Blood; 2019 Oct; 134(16):1323-1336. PubMed ID: 31492675
[TBL] [Abstract] [Full Text] [Related]
12. A Noncanonical Function of Polycomb Repressive Complexes Promotes Human Cytomegalovirus Lytic DNA Replication and Serves as a Novel Cellular Target for Antiviral Intervention.
Svrlanska A; Reichel A; Schilling EM; Scherer M; Stamminger T; Reuter N
J Virol; 2019 May; 93(9):. PubMed ID: 30814291
[TBL] [Abstract] [Full Text] [Related]
13. PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.
Ariës IM; Bodaar K; Karim SA; Chonghaile TN; Hinze L; Burns MA; Pfirrmann M; Degar J; Landrigan JT; Balbach S; Peirs S; Menten B; Isenhart R; Stevenson KE; Neuberg DS; Devidas M; Loh ML; Hunger SP; Teachey DT; Rabin KR; Winter SS; Dunsmore KP; Wood BL; Silverman LB; Sallan SE; Van Vlierberghe P; Orkin SH; Knoechel B; Letai AG; Gutierrez A
J Exp Med; 2018 Dec; 215(12):3094-3114. PubMed ID: 30404791
[TBL] [Abstract] [Full Text] [Related]
14. Clinical and biological relevance of genetic alterations in pediatric T-cell acute lymphoblastic leukemia in Taiwan.
Yeh TC; Liang DC; Liu HC; Jaing TH; Chen SH; Hou JY; Yang CP; Huang YJ; Yao HW; Huang TY; Lin TH; Shih LY
Pediatr Blood Cancer; 2019 Jan; 66(1):e27496. PubMed ID: 30280491
[TBL] [Abstract] [Full Text] [Related]
15. Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia.
Leeksma AC; Taylor J; Wu B; Gardner JR; He J; Nahas M; Gonen M; Alemayehu WG; Te Raa D; Walther T; Hüllein J; Dietrich S; Claus R; de Boer F; de Heer K; Dubois J; Dampmann M; Dürig J; van Oers MHJ; Geisler CH; Eldering E; Levine RL; Miller V; Mughal T; Lamanna N; Frattini MG; Heaney ML; Zelenetz A; Zenz T; Abdel-Wahab O; Kater AP
Leukemia; 2019 Feb; 33(2):390-402. PubMed ID: 30038380
[TBL] [Abstract] [Full Text] [Related]
16. Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds.
León-González AJ; Jara-Palacios MJ; Abbas M; Heredia FJ; Schini-Kerth VB
Food Funct; 2017 Nov; 8(11):4062-4069. PubMed ID: 28976514
[TBL] [Abstract] [Full Text] [Related]
17. Green tea polyphenol EGCG causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells.
Borutinskaitė V; Virkšaitė A; Gudelytė G; Navakauskienė R
Leuk Lymphoma; 2018 Feb; 59(2):469-478. PubMed ID: 28641467
[TBL] [Abstract] [Full Text] [Related]
18. Association of the long non-coding RNA MALAT1 with the polycomb repressive complex pathway in T and NK cell lymphoma.
Kim SH; Kim SH; Yang WI; Kim SJ; Yoon SO
Oncotarget; 2017 May; 8(19):31305-31317. PubMed ID: 28412742
[TBL] [Abstract] [Full Text] [Related]
19. WHO 2016 classification: changes and advancements in the diagnosis of miscellaneous primary CNS tumours.
Sahm F; Reuss DE; Giannini C
Neuropathol Appl Neurobiol; 2018 Feb; 44(2):163-171. PubMed ID: 28295484
[TBL] [Abstract] [Full Text] [Related]
20. An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Qi W; Zhao K; Gu J; Huang Y; Wang Y; Zhang H; Zhang M; Zhang J; Yu Z; Li L; Teng L; Chuai S; Zhang C; Zhao M; Chan H; Chen Z; Fang D; Fei Q; Feng L; Feng L; Gao Y; Ge H; Ge X; Li G; Lingel A; Lin Y; Liu Y; Luo F; Shi M; Wang L; Wang Z; Yu Y; Zeng J; Zeng C; Zhang L; Zhang Q; Zhou S; Oyang C; Atadja P; Li E
Nat Chem Biol; 2017 Apr; 13(4):381-388. PubMed ID: 28135235
[TBL] [Abstract] [Full Text] [Related]
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