BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Clinical Outcome
32 results:

  • 1. Machine learning developed a PI3K/akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer.
    Han X; Yang L; Tian H; Ji Y
    Aging (Albany NY); 2023 Oct; 15(20):11162-11183. PubMed ID: 37851341
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Pancancer analysis of SKA1 mutation and its association with the diagnosis and prognosis of human cancers.
    Lan H; Yuan J; Zhang R; Jiang B; Li Q; Huang Z; Chen P; Xiang H; Zeng X; Xiao S
    Genomics; 2023 Mar; 115(2):110554. PubMed ID: 36587749
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Modulation of intracellular kinase signaling to improve TIL stemness and function for adoptive cell therapy.
    Feng H; Qiu L; Shi Z; Sheng Y; Zhao P; Zhou D; Li F; Yu H; You Y; Wang H; Li M; Zhu S; Du Y; Cui J; Sun J; Liu Y; Jiang H; Wu X
    Cancer Med; 2023 Feb; 12(3):3313-3327. PubMed ID: 36028997
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers.
    Kong B; Han CY; Kim SI; Patten DA; Han Y; Carmona E; Shieh DB; Cheung AC; Mes-Masson AM; Harper ME; Song YS; Tsang BK
    J Ovarian Res; 2022 Jun; 15(1):70. PubMed ID: 35668443
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Ascites-derived ALDH+CD44+ tumour cell subsets endow stemness, metastasis and metabolic switch via PDK4-mediated STAT3/akt/NF-κB/IL-8 signalling in ovarian cancer.
    Jiang YX; Siu MK; Wang JJ; Mo XT; Leung TH; Chan DW; Cheung AN; Ngan HY; Chan KK
    Br J Cancer; 2020 Jul; 123(2):275-287. PubMed ID: 32390009
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Genome-wide DNA copy number profiling and bioinformatics analysis of ovarian cancer reveals key genes and pathways associated with distinct invasive/migratory capabilities.
    Liu G; Ruan G; Huang M; Chen L; Sun P
    Aging (Albany NY); 2020 Jan; 12(1):178-192. PubMed ID: 31895688
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
    Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
    Cancer Lett; 2020 Jan; 469():195-206. PubMed ID: 31672491
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Influence of p53 Isoform Expression on Survival in High-Grade Serous ovarian cancers.
    Bischof K; Knappskog S; Hjelle SM; Stefansson I; Woie K; Salvesen HB; Gjertsen BT; Bjorge L
    Sci Rep; 2019 Mar; 9(1):5244. PubMed ID: 30918304
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. CD24 expression is a marker for predicting clinical outcome and regulates the epithelial-mesenchymal transition in ovarian cancer via both the akt and ERK pathways.
    Nakamura K; Terai Y; Tanabe A; Ono YJ; Hayashi M; Maeda K; Fujiwara S; Ashihara K; Nakamura M; Tanaka Y; Tanaka T; Tsunetoh S; Sasaki H; Ohmichi M
    Oncol Rep; 2017 Jun; 37(6):3189-3200. PubMed ID: 28440503
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. In-vitro and in-vivo combined effect of ARQ 092, an akt inhibitor, with ARQ 087, a FGFR inhibitor.
    Yu Y; Hall T; Eathiraj S; Wick MJ; Schwartz B; Abbadessa G
    Anticancer Drugs; 2017 Jun; 28(5):503-513. PubMed ID: 28240679
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Amplification of USP13 drives ovarian cancer metabolism.
    Han C; Yang L; Choi HH; Baddour J; Achreja A; Liu Y; Li Y; Li J; Wan G; Huang C; Ji G; Zhang X; Nagrath D; Lu X
    Nat Commun; 2016 Nov; 7():13525. PubMed ID: 27892457
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A novel p70 S6 kinase-microRNA biogenesis axis mediates multicellular spheroid formation in ovarian cancer progression.
    Lam SS; Ip CK; Mak AS; Wong AS
    Oncotarget; 2016 Jun; 7(25):38064-38077. PubMed ID: 27191261
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. CCNE1 copy-number gain and overexpression identify ovarian clear cell carcinoma with a poor prognosis.
    Ayhan A; Kuhn E; Wu RC; Ogawa H; Bahadirli-Talbott A; Mao TL; Sugimura H; Shih IM; Wang TL
    Mod Pathol; 2017 Feb; 30(2):297-303. PubMed ID: 27767100
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis.
    Sestito R; Cianfrocca R; Rosanò L; Tocci P; Di Castro V; Caprara V; Bagnato A
    Life Sci; 2016 Aug; 159():43-48. PubMed ID: 26776834
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma.
    Siamakpour-Reihani S; Owzar K; Jiang C; Turner T; Deng Y; Bean SM; Horton JK; Berchuck A; Marks JR; Dewhirst MW; Alvarez Secord A
    Gynecol Oncol; 2015 Oct; 139(1):23-9. PubMed ID: 26260910
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. COL11A1 confers chemoresistance on ovarian cancer cells through the activation of akt/c/EBPβ pathway and PDK1 stabilization.
    Wu YH; Chang TH; Huang YF; Chen CC; Chou CY
    Oncotarget; 2015 Sep; 6(27):23748-63. PubMed ID: 26087191
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion.
    Rao TD; Tian H; Ma X; Yan X; Thapi S; Schultz N; Rosales N; Monette S; Wang A; Hyman DM; Levine DA; Solit D; Spriggs DR
    PLoS One; 2015; 10(5):e0126633. PubMed ID: 25965947
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Fibroblast growth factor receptor 2 is associated with poor overall survival in clear cell carcinoma of the ovary and may be a novel therapeutic approach.
    Itamochi H; Oumi N; Oishi T; Taniguchi F; Shoji T; Fujiwara H; Sugiyama T; Suzuki M; Kigawa J; Harada T
    Int J Gynecol Cancer; 2015 May; 25(4):570-6. PubMed ID: 25756405
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Dualistic classification of epithelial ovarian cancer: surgical and survival outcomes in a large retrospective series.
    Panici PB; Marchetti C; Salerno L; Musella A; Vertechy L; Palaia I; Perniola G; Ruscito I; Boni T; Angioli R; Muzii L
    Ann Surg Oncol; 2014 Sep; 21(9):3036-41. PubMed ID: 24770721
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Promoter CpG island methylation of genes in key cancer pathways associates with clinical outcome in high-grade serous ovarian cancer.
    Dai W; Zeller C; Masrour N; Siddiqui N; Paul J; Brown R
    Clin Cancer Res; 2013 Oct; 19(20):5788-5797. PubMed ID: 23965899
    [TBL] [Abstract] [Full Text] [Related]  


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