BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND BRCA1, BRCAI, 672, ENSG00000012048, IRIS, BRCC1, RNF53, PSCP AND Treatment
1202 results:

  • 1. Germline mutations in brca1 and BRCA2 among Brazilian women with ovarian cancer treated in the Public Health System.
    de Oliveira Ferreira C; Carneiro VCG; Araujo Mariz C
    BMC Cancer; 2024 Apr; 24(1):499. PubMed ID: 38641594
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A Study on the Retrospective Reinterpretation of brca1 and BRCA2 Variants.
    Kim JJ; Kim DJ; Nam EJ; Song KE; Ham JY; Kim YK; Lee NY
    Clin Lab; 2024 Apr; 70(4):. PubMed ID: 38623660
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing.
    Kong D; Wu Y; Liu Q; Huang C; Wang T; Huang Z; Gao Y; Li Y; Guo H
    Eur J Med Res; 2024 Apr; 29(1):231. PubMed ID: 38609993
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Olaparib Addition to Maintenance Bevacizumab Therapy in ovarian Carcinoma With BRCA-Like Genomic Aberrations.
    Schouten PC; Schmidt S; Becker K; Thiele H; Nürnberg P; Richters L; Ernst C; Treilleux I; Medioni J; Heitz F; Pisano C; Garcia Y; Petru E; Hietanen S; Colombo N; Vergote I; Nagao S; Linn SC; Pujade-Lauraine E; Ray-Coquard I; Harter P; Hahnen E; Schmutzler RK
    JAMA Netw Open; 2024 Apr; 7(4):e245552. PubMed ID: 38592722
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Targeting PARG induces tumor cell growth inhibition and antitumor immune response by reducing phosphorylated STAT3 in ovarian cancer.
    Martincuks A; Zhang C; Austria T; Li YJ; Huang R; Lugo Santiago N; Kohut A; Zhao Q; Borrero RM; Shen B; Cristea M; Wang EW; Song M; Rodriguez-Rodriguez L; Yu H
    J Immunother Cancer; 2024 Apr; 12(4):. PubMed ID: 38580335
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Olaparib not cost-effective as maintenance therapy for platinum-sensitive, brca1/2 germline-mutated metastatic pancreatic cancer.
    Mehra T; Lupatsch JE; Kössler T; Dedes K; Siebenhüner AR; von Moos R; Wicki A; Schwenkglenks ME
    PLoS One; 2024; 19(4):e0301271. PubMed ID: 38573891
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Population-based BRCA germline mutation screening in the Han Chinese identifies individuals at risk of BRCA mutation-related cancer: experience from a clinical diagnostic center from greater Shanghai area.
    Wu Z; Zhang Q; Jin Y; Zhang X; Chen Y; Yang C; Tang X; Jiang H; Wang X; Zhou X; Yu F; Wang B; Guan M
    BMC Cancer; 2024 Apr; 24(1):411. PubMed ID: 38566028
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. High Concordance of Different Assays in the Determination of Homologous Recombination Deficiency-Associated Genomic Instability in ovarian cancer.
    Pfarr N; von Schwarzenberg K; Zocholl D; Merkelbach-Bruse S; Siemanowski J; Mayr EM; Herold S; Kleo K; Heukamp LC; Willing EM; Menzel M; Lehmann U; Bartels S; Chakraborty S; Baretton G; Demes MC; Döring C; Kazdal D; Budczies J; Rad R; Wild P; Christinat Y; McKee T; Schirmacher P; Horst D; Büttner R; Stenzinger A; Sehouli J; Vollbrecht C; Hummel M; Braicu EI; Weichert W;
    JCO Precis Oncol; 2024 Mar; 8():e2300348. PubMed ID: 38513168
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  • 9. Oncological outcomes of intraperitoneal chemotherapy in advanced ovarian cancer: BRCA mutation role.
    Padilla-Iserte P; Iváñez M; Muruzabal JC; Navarro R; Díaz-Feijoo B; Iacoponi S; García-Pineda V; Díaz C; Utrilla-Layna J; Gil-Moreno A; Serra A; Gilabert-Estellés J; Martínez Canto C; Tejerizo Á; Lago V; Cárdenas-Rebollo JM; Domingo S;
    Eur J Surg Oncol; 2024 Apr; 50(4):108263. PubMed ID: 38492526
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. A real-world study of treatment patterns following disease progression in epithelial ovarian cancer patients undergoing poly-ADP-ribose polymerase inhibitor maintenance therapy.
    Zhang N; Zheng H; Gao Y; Shu T; Wang H; Cai Y
    J Ovarian Res; 2024 Mar; 17(1):55. PubMed ID: 38444005
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Abrogation of KLF5 sensitizes
    Zhang Z; Liu Y; Xu Y; Xu Z; Jia J; Jin Y; Wang W; Liu L
    Acta Biochim Biophys Sin (Shanghai); 2024 Apr; 56(4):576-585. PubMed ID: 38433576
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Successful Management of ovarian cancer Progressing on Olaparib by Niraparib Following Cytoreduction: A Case Report.
    Endo Y; Kamo N; Kato A; Sato T; Okabe C; Furukawa S; Watanabe T; Soeda S
    In Vivo; 2024; 38(2):958-962. PubMed ID: 38418162
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Precision Medicine in Castration-Resistant Prostate cancer: Advances, Challenges, and the Landscape of PARPi Therapy-A Narrative Review.
    Dimitrov G; Mangaldzhiev R; Slavov C; Popov E
    Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396858
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Complexity of the Genetic Background of Oncogenesis in ovarian cancer-Genetic Instability and Clinical Implications.
    Murawski M; Jagodziński A; Bielawska-Pohl A; Klimczak A
    Cells; 2024 Feb; 13(4):. PubMed ID: 38391958
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Prevalence and spectrum of germline brca1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health.
    De Matteis E; Tumolo MR; Tarantino P; Ciccarese M; Grassi T; Bagordo F; De Giorgio MR; Rizzo E; Ronzino G
    Oncotarget; 2024 Feb; 15():134-141. PubMed ID: 38386807
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Targeting BRCA and PALB2 in Pancreatic cancer.
    Anbil S; Reiss KA
    Curr Treat Options Oncol; 2024 Mar; 25(3):346-363. PubMed ID: 38311708
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. brca1, BRCA2, and TP53 germline and somatic variants and clinicopathological characteristics of Brazilian patients with epithelial ovarian cancer.
    Richau CS; Scherer NM; Matta BP; de Armas EM; de Barros Moreira FC; Bergmann A; Pereira Chaves CB; Boroni M; Dos Santos ACE; Moreira MAM
    Cancer Med; 2024 Feb; 13(3):e6729. PubMed ID: 38308422
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Patient-Reported Outcomes in OlympiA: A Phase III, Randomized, Placebo-Controlled Trial of Adjuvant Olaparib in g
    Ganz PA; Bandos H; Španić T; Friedman S; Müller V; Kuemmel S; Delaloge S; Brain E; Toi M; Yamauchi H; de Dueñas EM; Armstrong A; Im SA; Song CG; Zheng H; Sarosiek T; Sharma P; Geng C; Fu P; Rhiem K; Frauchiger-Heuer H; Wimberger P; t'Kint de Roodenbeke D; Liao N; Goodwin A; Chakiba-Brugère C; Friedlander M; Lee KS; Giacchetti S; Takano T; Henao-Carrasco F; Virani S; Valdes-Albini F; Domchek SM; Bane C; McCarron EC; Mita M; Rossi G; Rastogi P; Fielding A; Gelber RD; Scheepers ED; Cameron D; Garber J; Geyer CE; Tutt ANJ
    J Clin Oncol; 2024 Apr; 42(11):1288-1300. PubMed ID: 38301187
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Reclassifying brca1 c.4358-2A > G and BRCA2 c.475 + 5G > C variants from "Uncertain Significance" to "Pathogenic" based on minigene assays and clinical evidence.
    Ning Y; Zhang Y; Tian T; Chen Y; Wang J; Lei K; Cui Z
    J Cancer Res Clin Oncol; 2024 Feb; 150(2):62. PubMed ID: 38300310
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Results of a randomised Phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer.
    Nicum S; McGregor N; Austin R; Collins L; Dutton S; McNeish I; Glasspool R; Hall M; Roux R; Michael A; Clamp A; Jayson G; Kristeleit R; Banerjee S; Mansouri A
    Br J Cancer; 2024 Apr; 130(6):941-950. PubMed ID: 38245661
    [TBL] [Abstract] [Full Text] [Related]  


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