BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND FANCD2, FANCD, 2177, ENSG00000144554, FLJ23826, FAD, FACD, FA4, FA-D2, FAD2, DKFZp762A223
58 results:

  • 1. SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers.
    Lu Z; Mao W; Yang H; Santiago-O'Farrill JM; Rask PJ; Mondal J; Chen H; Ivan C; Liu X; Liu CG; Xi Y; Masuda K; Carrami EM; Chen M; Tang Y; Pang L; Lakomy DS; Calin GA; Liang H; Ahmed AA; Vankayalapati H; Bast RC
    J Clin Invest; 2022 Jun; 132(11):. PubMed ID: 35642638
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Evaluation of conformational transitions of h-BRCA2 functional domain and unclassified variant Arg2502Cys using multimodal approach.
    Khan MA; Siddiqui MQ; Kuligina E; Varma AK
    Int J Biol Macromol; 2022 Jun; 209(Pt A):716-724. PubMed ID: 35413318
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Silencing of FANCI Promotes DNA Damage and Sensitizes ovarian cancer Cells to Carboplatin.
    Li Y; Zhang Y; Yang Q; Zhou X; Guo Y; Ding F; Liu Z; Luo A
    Curr Cancer Drug Targets; 2022; 22(7):591-602. PubMed ID: 35362384
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene.
    Fierheller CT; Guitton-Sert L; Alenezi WM; Revil T; Oros KK; Gao Y; Bedard K; Arcand SL; Serruya C; Behl S; Meunier L; Fleury H; Fewings E; Subramanian DN; Nadaf J; Bruce JP; Bell R; Provencher D; Foulkes WD; El Haffaf Z; Mes-Masson AM; Majewski J; Pugh TJ; Tischkowitz M; James PA; Campbell IG; Greenwood CMT; Ragoussis J; Masson JY; Tonin PN
    Genome Med; 2021 Dec; 13(1):186. PubMed ID: 34861889
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Hedgehog/GLI1 Transcriptionally Regulates fancd2 in ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition.
    Mani C; Tripathi K; Chaudhary S; Somasagara RR; Rocconi RP; Crasto C; Reedy M; Athar M; Palle K
    Neoplasia; 2021 Sep; 23(9):1002-1015. PubMed ID: 34380074
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro.
    McGlorthan L; Paucarmayta A; Casablanca Y; Maxwell GL; Syed V
    Apoptosis; 2021 Apr; 26(3-4):184-194. PubMed ID: 33515314
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Identification of Hub Genes in High-Grade Serous ovarian cancer Using Weighted Gene Co-Expression Network Analysis.
    Wu M; Sun Y; Wu J; Liu G
    Med Sci Monit; 2020 Mar; 26():e922107. PubMed ID: 32180586
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. CRL4 ubiquitin ligase stimulates Fanconi anemia pathway-induced single-stranded DNA-RPA signaling.
    Codilupi T; Taube D; Naegeli H
    BMC Cancer; 2019 Nov; 19(1):1042. PubMed ID: 31690264
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Analysis of polymorphisms in genes associated with the FA/BRCA pathway in three patients with multiple primary malignant neoplasms.
    Wang L; Wang H; Wang T; Liu J; Chen W; Wang Y; Chen C; Zhu H; Dai P
    Artif Cells Nanomed Biotechnol; 2019 Dec; 47(1):1101-1112. PubMed ID: 30942098
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Clinical importance of fancd2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas.
    Moes-Sosnowska J; Rzepecka IK; Chodzynska J; Dansonka-Mieszkowska A; Szafron LM; Balabas A; Lotocka R; Sobiczewski P; Kupryjanczyk J
    Cancer Biol Ther; 2019; 20(6):843-854. PubMed ID: 30822218
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer.
    Paulo P; Maia S; Pinto C; Pinto P; Monteiro A; Peixoto A; Teixeira MR
    PLoS Genet; 2018 Apr; 14(4):e1007355. PubMed ID: 29659569
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Fanconi anaemia and cancer: an intricate relationship.
    Nalepa G; Clapp DW
    Nat Rev Cancer; 2018 Mar; 18(3):168-185. PubMed ID: 29376519
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A homozygous
    Fouquet B; Pawlikowska P; Caburet S; Guigon C; Mäkinen M; Tanner L; Hietala M; Urbanska K; Bellutti L; Legois B; Bessieres B; Gougeon A; Benachi A; Livera G; Rosselli F; Veitia RA; Misrahi M
    Elife; 2017 Dec; 6():. PubMed ID: 29231814
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Overlooked fancd2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression.
    Han B; Shen Y; Zhang P; Jayabal P; Che R; Zhang J; Yu H; Fei P
    Oncotarget; 2017 Apr; 8(14):22490-22500. PubMed ID: 28157704
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. BLM promotes the activation of Fanconi Anemia signaling pathway.
    Panneerselvam J; Wang H; Zhang J; Che R; Yu H; Fei P
    Oncotarget; 2016 May; 7(22):32351-61. PubMed ID: 27083049
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. ovarian Microcystic Stromal Tumor: A Rare Clinical Manifestation of Familial Adenomatous Polyposis.
    Liu C; Gallagher RL; Price GR; Bolton E; Joy C; Harraway J; Venter DJ; Armes JE
    Int J Gynecol Pathol; 2016 Nov; 35(6):561-565. PubMed ID: 27015438
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome.
    Menendez JA; Folguera-Blasco N; Cuyàs E; Fernández-Arroyo S; Joven J; Alarcón T
    Oncotarget; 2016 Mar; 7(11):11959-71. PubMed ID: 26943589
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Targeted next-generation sequencing for molecular diagnosis of endometriosis-associated ovarian cancer.
    Er TK; Su YF; Wu CC; Chen CC; Wang J; Hsieh TH; Herreros-Villanueva M; Chen WT; Chen YT; Liu TC; Chen HS; Tsai EM
    J Mol Med (Berl); 2016 Jul; 94(7):835-47. PubMed ID: 26920370
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Safety, Costs, and Efficacy of Rapid Drug Desensitizations to Chemotherapy and Monoclonal Antibodies.
    Sloane D; Govindarajulu U; Harrow-Mortelliti J; Barry W; Hsu FI; Hong D; Laidlaw T; Palis R; Legere H; Bunyavanich S; Breslow R; Wesemann D; Barrett N; Brennan P; Chong HJ; Liu A; Fernandez J; Fanning L; Kyin T; Cahill K; Bankova L; Lynch A; Berlin S; Campos S; Fuchs C; Mayer R; Matulonis U; Castells M
    J Allergy Clin Immunol Pract; 2016; 4(3):497-504. PubMed ID: 26895621
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair.
    Villalona-Calero MA; Duan W; Zhao W; Shilo K; Schaaf LJ; Thurmond J; Westman JA; Marshall J; Xiaobai L; Ji J; Rose J; Lustberg M; Bekaii-Saab T; Chen A; Timmers C
    J Natl Cancer Inst; 2016 Jul; 108(7):. PubMed ID: 26848151
    [TBL] [Abstract] [Full Text] [Related]  


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