BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND FANCD2, FANCD, 2177, ENSG00000144554, FLJ23826, FAD, FACD, FA4, FA-D2, FAD2, DKFZp762A223 AND Treatment
19 results:

  • 1. SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers.
    Lu Z; Mao W; Yang H; Santiago-O'Farrill JM; Rask PJ; Mondal J; Chen H; Ivan C; Liu X; Liu CG; Xi Y; Masuda K; Carrami EM; Chen M; Tang Y; Pang L; Lakomy DS; Calin GA; Liang H; Ahmed AA; Vankayalapati H; Bast RC
    J Clin Invest; 2022 Jun; 132(11):. PubMed ID: 35642638
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene.
    Fierheller CT; Guitton-Sert L; Alenezi WM; Revil T; Oros KK; Gao Y; Bedard K; Arcand SL; Serruya C; Behl S; Meunier L; Fleury H; Fewings E; Subramanian DN; Nadaf J; Bruce JP; Bell R; Provencher D; Foulkes WD; El Haffaf Z; Mes-Masson AM; Majewski J; Pugh TJ; Tischkowitz M; James PA; Campbell IG; Greenwood CMT; Ragoussis J; Masson JY; Tonin PN
    Genome Med; 2021 Dec; 13(1):186. PubMed ID: 34861889
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Hedgehog/GLI1 Transcriptionally Regulates fancd2 in ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition.
    Mani C; Tripathi K; Chaudhary S; Somasagara RR; Rocconi RP; Crasto C; Reedy M; Athar M; Palle K
    Neoplasia; 2021 Sep; 23(9):1002-1015. PubMed ID: 34380074
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro.
    McGlorthan L; Paucarmayta A; Casablanca Y; Maxwell GL; Syed V
    Apoptosis; 2021 Apr; 26(3-4):184-194. PubMed ID: 33515314
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Identification of Hub Genes in High-Grade Serous ovarian cancer Using Weighted Gene Co-Expression Network Analysis.
    Wu M; Sun Y; Wu J; Liu G
    Med Sci Monit; 2020 Mar; 26():e922107. PubMed ID: 32180586
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. CRL4 ubiquitin ligase stimulates Fanconi anemia pathway-induced single-stranded DNA-RPA signaling.
    Codilupi T; Taube D; Naegeli H
    BMC Cancer; 2019 Nov; 19(1):1042. PubMed ID: 31690264
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Clinical importance of fancd2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas.
    Moes-Sosnowska J; Rzepecka IK; Chodzynska J; Dansonka-Mieszkowska A; Szafron LM; Balabas A; Lotocka R; Sobiczewski P; Kupryjanczyk J
    Cancer Biol Ther; 2019; 20(6):843-854. PubMed ID: 30822218
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Safety, Costs, and Efficacy of Rapid Drug Desensitizations to Chemotherapy and Monoclonal Antibodies.
    Sloane D; Govindarajulu U; Harrow-Mortelliti J; Barry W; Hsu FI; Hong D; Laidlaw T; Palis R; Legere H; Bunyavanich S; Breslow R; Wesemann D; Barrett N; Brennan P; Chong HJ; Liu A; Fernandez J; Fanning L; Kyin T; Cahill K; Bankova L; Lynch A; Berlin S; Campos S; Fuchs C; Mayer R; Matulonis U; Castells M
    J Allergy Clin Immunol Pract; 2016; 4(3):497-504. PubMed ID: 26895621
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Curcumin reverses cisplatin resistance in cisplatin-resistant lung caner cells by inhibiting FA/BRCA pathway.
    Chen P; Li J; Jiang HG; Lan T; Chen YC
    Tumour Biol; 2015 May; 36(5):3591-9. PubMed ID: 25542235
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Systemic anti-tumour effects of local thermally sensitive liposome therapy.
    Viglianti BL; Dewhirst MW; Boruta RJ; Park JY; Landon C; Fontanella AN; Guo J; Manzoor A; Hofmann CL; Palmer GM
    Int J Hyperthermia; 2014 Sep; 30(6):385-92. PubMed ID: 25164143
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Genomic and transcriptomic plasticity in treatment-naive ovarian cancer.
    Hoogstraat M; de Pagter MS; Cirkel GA; van Roosmalen MJ; Harkins TT; Duran K; Kreeftmeijer J; Renkens I; Witteveen PO; Lee CC; Nijman IJ; Guy T; van 't Slot R; Jonges TN; Lolkema MP; Koudijs MJ; Zweemer RP; Voest EE; Cuppen E; Kloosterman WP
    Genome Res; 2014 Feb; 24(2):200-11. PubMed ID: 24221193
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer.
    Colombo PE; Fabbro M; Theillet C; Bibeau F; Rouanet P; Ray-Coquard I
    Crit Rev Oncol Hematol; 2014 Feb; 89(2):207-16. PubMed ID: 24071502
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Gossypol induces apoptosis in ovarian cancer cells through oxidative stress.
    Wang J; Jin L; Li X; Deng H; Chen Y; Lian Q; Ge R; Deng H
    Mol Biosyst; 2013 Jun; 9(6):1489-97. PubMed ID: 23532321
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation.
    He M; Sun HG; Hao JY; Li YL; Yu JK; Yan YY; Zhao L; Li N; Wang Y; Bai XF; Yu ZJ; Zheng ZH; Mi XY; Wang EH; Wei MJ
    Oncol Rep; 2013 May; 29(5):1721-9. PubMed ID: 23440494
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Assessment of fancd2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents.
    Duan W; Gao L; Zhao W; Leon M; Sadee W; Webb A; Resnick K; Wu X; Ramaswamy B; Cohn DE; Shapiro C; Andreassen PR; Otterson GA; Villalona-Calero MA
    Transl Res; 2013 Mar; 161(3):156-64. PubMed ID: 23063585
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin.
    Jacquemont C; Simon JA; D'Andrea AD; Taniguchi T
    Mol Cancer; 2012 Apr; 11():26. PubMed ID: 22537224
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. BRCAness profile of sporadic ovarian cancer predicts disease recurrence.
    Wysham WZ; Mhawech-Fauceglia P; Li H; Hays L; Syriac S; Skrepnik T; Wright J; Pande N; Hoatlin M; Pejovic T
    PLoS One; 2012; 7(1):e30042. PubMed ID: 22253870
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Fanconi anemia D2 protein confers chemoresistance in response to the anticancer agent, irofulven.
    Wang Y; Wiltshire T; Senft J; Wenger SL; Reed E; Wang W
    Mol Cancer Ther; 2006 Dec; 5(12):3153-61. PubMed ID: 17172419
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring.
    Kirkpatrick ND; Zou C; Brewer MA; Brands WR; Drezek RA; Utzinger U
    Photochem Photobiol; 2005; 81(1):125-34. PubMed ID: 15535738
    [TBL] [Abstract] [Full Text] [Related]  


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