BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND FH, HLRCC, 2271, ENSG00000091483, MCUL1, MCL, LRCC, P07954 AND Treatment
72 results:

  • 1. TCEB3 initiates ovarian cancer apoptosis by mediating ubiquitination and degradation of mcl-1.
    Cai Y; Li Y; Xu Y; Yang W; Huang M
    FASEB J; 2024 Apr; 38(8):e23625. PubMed ID: 38661028
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Pan-EGFR Inhibitor Dacomitinib Resensitizes Paclitaxel and Induces Apoptosis via Elevating Intracellular ROS Levels in ovarian cancer SKOV3-TR Cells.
    Lim YJ; Kim HS; Bae S; So KA; Kim TJ; Lee JH
    Molecules; 2024 Jan; 29(1):. PubMed ID: 38202856
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Secondary (additional) findings from the 100,000 Genomes Project: Disease manifestation, health care outcomes, and costs of disclosure.
    Nolan J; Buchanan J; Taylor J; Almeida J; Bedenham T; Blair E; Broadgate S; Butler S; Cazeaux A; Craft J; Cranston T; Crawford G; Forrest J; Gabriel J; George E; Gillen D; Haeger A; Hastings Ward J; Hawkes L; Hodgkiss C; Hoffman J; Jones A; Karpe F; Kasperaviciute D; Kovacs E; Leigh S; Limb E; Lloyd-Jani A; Lopez J; Lucassen A; McFarlane C; O'Rourke AW; Pond E; Sherman C; Stewart H; Thomas E; Thomas S; Thomas T; Thomson K; Wakelin H; Walker S; Watson M; Williams E; Ormondroyd E
    Genet Med; 2024 Mar; 26(3):101051. PubMed ID: 38131308
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Bcl-2 family inhibitors sensitize human cancer models to therapy.
    Valentini E; Di Martile M; Brignone M; Di Caprio M; Manni I; Chiappa M; Sergio I; Chiacchiarini M; Bazzichetto C; Conciatori F; D'Aguanno S; D'Angelo C; Ragno R; Russillo M; Colotti G; Marchesi F; Bellone ML; Dal Piaz F; Felli MP; Damia G; Del Bufalo D
    Cell Death Dis; 2023 Jul; 14(7):441. PubMed ID: 37460459
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. LS-007 inhibits melanoma growth via inducing apoptosis and cell cycle arrest and regulating macrophage polarization.
    Yin L; Liu X; Wu J; Yang J; Wang J; Dou H; Hou Y
    Melanoma Res; 2022 Dec; 32(6):419-427. PubMed ID: 36094494
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Inhibition of Glutamine Uptake Resensitizes Paclitaxel Resistance in SKOV3-TR ovarian cancer Cell via mTORC1/S6K Signaling Pathway.
    Kim G; Jang SK; Kim YJ; Jin HO; Bae S; Hong J; Park IC; Lee JH
    Int J Mol Sci; 2022 Aug; 23(15):. PubMed ID: 35955892
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Identification of immunity- and ferroptosis-related genes for predicting the prognosis of serous ovarian cancer.
    Yuan X; Zhou Q; Zhang F; Zheng W; Liu H; Chen A; Tao Y
    Gene; 2022 Sep; 838():146701. PubMed ID: 35777713
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human ovarian cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesenchymal Transition Pathways.
    Therachiyil L; Krishnankutty R; Ahmad F; Mateo JM; Uddin S; Korashy HM
    Int J Mol Sci; 2022 Jun; 23(12):. PubMed ID: 35742838
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A phase II study of Navitoclax (ABT-263) as single agent in women heavily pretreated for recurrent epithelial ovarian cancer: The MONAVI - GINECO study.
    Joly F; Fabbro M; Follana P; Lequesne J; Medioni J; Lesoin A; Frenel JS; Abadie-Lacourtoisie S; Floquet A; Gladieff L; You B; Gavoille C; Kalbacher E; Briand M; Brachet PE; Giffard F; Weiswald LB; Just PA; Blanc-Fournier C; Leconte A; Clarisse B; Leary A; Poulain L
    Gynecol Oncol; 2022 Apr; 165(1):30-39. PubMed ID: 35123771
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Kaempferia parviflora extract inhibits TNF-α-induced release of MCP-1 in ovarian cancer cells through the suppression of NF-κB signaling.
    Thaklaewphan P; Ruttanapattanakul J; Monkaew S; Buatoom M; Sookkhee S; Nimlamool W; Potikanond S
    Biomed Pharmacother; 2021 Sep; 141():111911. PubMed ID: 34328090
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The cyclin-dependent kinase inhibitor AT7519 augments cisplatin's efficacy in ovarian cancer via multiple oncogenic signaling pathways.
    Wang L; Chen Y; Li H; Xu Q; Liu R
    Fundam Clin Pharmacol; 2022 Feb; 36(1):81-88. PubMed ID: 34212421
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells.
    Zhong Y; Le F; Cheng J; Luo C; Zhang X; Wu X; Xu F; Zuo Q; Tan B
    Oncol Rep; 2021 May; 45(5):. PubMed ID: 33760192
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of mcl-1 through autophagy.
    Hu X; Xia M; Wang J; Yu H; Chai J; Zhang Z; Sun Y; Su J; Sun L
    Biomed Pharmacother; 2020 Sep; 129():110397. PubMed ID: 32585451
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Bim, Puma and Noxa upregulation by Naftopidil sensitizes ovarian cancer to the BH3-mimetic ABT-737 and the MEK inhibitor Trametinib.
    Florent R; Weiswald LB; Lambert B; Brotin E; Abeilard E; Louis MH; Babin G; Poulain L; N'Diaye M
    Cell Death Dis; 2020 May; 11(5):380. PubMed ID: 32424251
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Revisiting the Genomic and Transcriptomic Landscapes from Female Malignancies Could Provide Molecular Markers and Targets for Precision Medicine.
    Taniguchi-Ponciano K; Huerta-Padilla V; Baeza-Xochihua V; Ponce-Navarrete G; Salcedo E; Gomez-Apo E; Chavez-Macias L; Aviles-Duran J; Ruiz-Sanchez H; Valdivia A; Peralta R; Romero-Anduaga H; Rosas-Vargas H; Quijano F; Salcedo M; Marrero-Rodríguez D
    Arch Med Res; 2019 Oct; 50(7):428-436. PubMed ID: 31783305
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer.
    Han Y; Wang Z; Sun S; Zhang Z; Liu J; Jin X; Wu P; Ji T; Ding W; Wang B; Gao Q
    Epigenetics; 2020; 15(1-2):122-133. PubMed ID: 31423895
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Boosting the apoptotic response of high-grade serous ovarian cancers with CCNE1 amplification to paclitaxel in vitro by targeting APC/C and the pro-survival protein mcl-1.
    Raab M; Kobayashi NF; Becker S; Kurunci-Csacsko E; Krämer A; Strebhardt K; Sanhaji M
    Int J Cancer; 2020 Feb; 146(4):1086-1098. PubMed ID: 31286496
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Akt inhibitor SC66 promotes cell sensitivity to cisplatin in chemoresistant ovarian cancer cells through inhibition of COL11A1 expression.
    Wu YH; Huang YF; Chen CC; Chou CY
    Cell Death Dis; 2019 Apr; 10(4):322. PubMed ID: 30975980
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. BRCA mutation testing for ovarian cancer in the context of available targeted therapy: Survey and consensus of Hong Kong specialists.
    Kwong A; Cheng KD; Hsue CV; Hui SK; Leung CR; Leung KA; Ngan KR; Soong SI
    Asia Pac J Clin Oncol; 2019 Mar; 15 Suppl 2():20-31. PubMed ID: 30838787
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Alpha-mangostin, an active compound in Garcinia mangostana, abrogates anoikis-resistance in human hepatocellular carcinoma cells.
    Wudtiwai B; Pitchakarn P; Banjerdpongchai R
    Toxicol In Vitro; 2018 Dec; 53():222-232. PubMed ID: 30195041
    [TBL] [Abstract] [Full Text] [Related]  


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