Terms: = Ovarian cancer AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
26 results:
1. Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer.
Adamson AW; Ding YC; Steele L; Leong LA; Morgan R; Wakabayashi MT; Han ES; Dellinger TH; Lin PS; Hakim AA; Wilczynski S; Warden CD; Tao S; Bedell V; Cristea MC; Neuhausen SL
J Ovarian Res; 2023 Jul; 16(1):141. PubMed ID: 37460928
[TBL] [Abstract] [Full Text] [Related]
2. mkk4 Inhibitors-Recent Development Status and Therapeutic Potential.
Katzengruber L; Sander P; Laufer S
Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108658
[TBL] [Abstract] [Full Text] [Related]
3. ROS-mediated SRMS activation confers platinum resistance in ovarian cancer.
Jiang Y; Song L; Lin Y; Nowialis P; Gao Q; Li T; Li B; Mao X; Song Q; Xing C; Zheng G; Huang S; Jin L
Oncogene; 2023 May; 42(20):1672-1684. PubMed ID: 37020040
[TBL] [Abstract] [Full Text] [Related]
4. Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division.
Cedeno-Rosario L; Honda D; Sunderland AM; Lewandowski MD; Taylor WR; Chadee DN
J Biol Chem; 2022 Aug; 298(8):102263. PubMed ID: 35843311
[TBL] [Abstract] [Full Text] [Related]
5. MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells.
Kleemann M; Schneider H; Unger K; Sander P; Schneider EM; Fischer-Posovszky P; Handrick R; Otte K
Sci Rep; 2018 Jun; 8(1):9020. PubMed ID: 29899543
[TBL] [Abstract] [Full Text] [Related]
6. TAp73-mediated the activation of c-Jun N-terminal kinase enhances cellular chemosensitivity to cisplatin in ovarian cancer cells.
Zhang P; Liu SS; Ngan HY
PLoS One; 2012; 7(8):e42985. PubMed ID: 22900074
[TBL] [Abstract] [Full Text] [Related]
7. Using mkk4's metastasis suppressor function to identify and dissect cancer cell-microenvironment interactions during metastatic colonization.
Krishnan V; Stadick N; Clark R; Bainer R; Veneris JT; Khan S; Drew A; Rinker-Schaeffer C
Cancer Metastasis Rev; 2012 Dec; 31(3-4):605-13. PubMed ID: 22706843
[TBL] [Abstract] [Full Text] [Related]
8. Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (mkk4)-mediated suppression of omental metastatic colonization.
Bainer RO; Veneris JT; Yamada SD; Montag A; Lingen MW; Gilad Y; Rinker-Schaeffer CW
Clin Exp Metastasis; 2012 Jun; 29(5):397-408. PubMed ID: 22350525
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9. Analysis of the mitogen-activated protein kinase kinase 4 (map2k4) tumor suppressor gene in ovarian cancer.
Davis SJ; Choong DY; Ramakrishna M; Ryland GL; Campbell IG; Gorringe KL
BMC Cancer; 2011 May; 11():173. PubMed ID: 21575258
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10. mkk4 acts as a potential tumor suppressor in ovarian cancer.
Yeasmin S; Nakayama K; Rahman MT; Rahman M; Ishikawa M; Katagiri A; Iida K; Nakayama N; Miyazaki K
Tumour Biol; 2011 Aug; 32(4):661-70. PubMed ID: 21487811
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11. Functional and clinicopathological analysis of loss of mkk4 expression in endometrial cancer.
Ishikawa M; Nakayama K; Rahman MT; Rahman M; Katagiri A; Iida K; Miyazaki K
Oncology; 2010; 79(3-4):238-46. PubMed ID: 21372598
[TBL] [Abstract] [Full Text] [Related]
12. Diverse somatic mutation patterns and pathway alterations in human cancers.
Kan Z; Jaiswal BS; Stinson J; Janakiraman V; Bhatt D; Stern HM; Yue P; Haverty PM; Bourgon R; Zheng J; Moorhead M; Chaudhuri S; Tomsho LP; Peters BA; Pujara K; Cordes S; Davis DP; Carlton VE; Yuan W; Li L; Wang W; Eigenbrot C; Kaminker JS; Eberhard DA; Waring P; Schuster SC; Modrusan Z; Zhang Z; Stokoe D; de Sauvage FJ; Faham M; Seshagiri S
Nature; 2010 Aug; 466(7308):869-73. PubMed ID: 20668451
[TBL] [Abstract] [Full Text] [Related]
13. Loss of mkk4 expression in ovarian cancer: a potential role for the epithelial to mesenchymal transition.
Yeasmin S; Nakayama K; Rahman MT; Rahman M; Ishikawa M; Katagiri A; Iida K; Nakayama N; Miyazaki K
Int J Cancer; 2011 Jan; 128(1):94-104. PubMed ID: 20309881
[TBL] [Abstract] [Full Text] [Related]
14. New paradigms for the function of jnkk1/mkk4 in controlling growth of disseminated cancer cells.
Taylor JL; Szmulewitz RZ; Lotan T; Hickson J; Griend DV; Yamada SD; Macleod K; Rinker-Schaeffer CW
Cancer Lett; 2008 Dec; 272(1):12-22. PubMed ID: 18572308
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15. c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.
Lotan T; Hickson J; Souris J; Huo D; Taylor J; Li T; Otto K; Yamada SD; Macleod K; Rinker-Schaeffer CW
Cancer Res; 2008 Apr; 68(7):2166-75. PubMed ID: 18381422
[TBL] [Abstract] [Full Text] [Related]
16. Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
Robinson VL; Shalhav O; Otto K; Kawai T; Gorospe M; Rinker-Schaeffer CW
Mol Cancer Res; 2008 Mar; 6(3):501-8. PubMed ID: 18337456
[TBL] [Abstract] [Full Text] [Related]
17. Role of mitogen-activated protein kinase kinase 4 in cancer.
Whitmarsh AJ; Davis RJ
Oncogene; 2007 May; 26(22):3172-84. PubMed ID: 17496914
[TBL] [Abstract] [Full Text] [Related]
18. Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products.
Shishodia S; Sethi G; Ahn KS; Aggarwal BB
Biochem Pharmacol; 2007 Jun; 74(1):118-30. PubMed ID: 17475222
[TBL] [Abstract] [Full Text] [Related]
19. Regulation of the metastasis suppressor gene mkk4 in ovarian cancer.
Spillman MA; Lacy J; Murphy SK; Whitaker RS; Grace L; Teaberry V; Marks JR; Berchuck A
Gynecol Oncol; 2007 May; 105(2):312-20. PubMed ID: 17276500
[TBL] [Abstract] [Full Text] [Related]
20. Homozygous deletion of mkk4 in ovarian serous carcinoma.
Nakayama K; Nakayama N; Davidson B; Katabuchi H; Kurman RJ; Velculescu VE; Shih IeM; Wang TL
Cancer Biol Ther; 2006 Jun; 5(6):630-4. PubMed ID: 16627982
[TBL] [Abstract] [Full Text] [Related]
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