Terms: = Ovarian cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
49 results:
1. Targeted inhibition of the ATR/CHK1 pathway overcomes resistance to olaparib and dysregulates DNA damage response protein expression in BRCA2
Biegała Ł; Gajek A; Szymczak-Pajor I; Marczak A; Śliwińska A; Rogalska A
Sci Rep; 2023 Dec; 13(1):22659. PubMed ID: 38114660
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2. Optimized spirooxindole-pyrazole hybrids targeting the p53-mdm2 interplay induce apoptosis and synergize with doxorubicin in A549 cells.
Islam MS; Al-Majid AM; Sholkamy EN; Barakat A; Viale M; Menichini P; Speciale A; Loiacono F; Azam M; Verma VP; Yousuf S; Teleb M
Sci Rep; 2023 May; 13(1):7441. PubMed ID: 37156796
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3. treatment for ovarian clear cell carcinoma with combined inhibition of WEE1 and ATR.
Chien W; Tyner JW; Gery S; Zheng Y; Li LY; Gopinatha Pillai MS; Nam C; Bhowmick NA; Lin DC; Koeffler HP
J Ovarian Res; 2023 Apr; 16(1):80. PubMed ID: 37087441
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4. Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma.
Murumägi A; Ungureanu D; Khan S; Arjama M; Välimäki K; Ianevski A; Ianevski P; Bergström R; Dini A; Kanerva A; Koivisto-Korander R; Tapper J; Lassus H; Loukovaara M; Mägi A; Hirasawa A; Aoki D; Pietiäinen V; Pellinen T; Bützow R; Aittokallio T; Kallioniemi O
Br J Cancer; 2023 Feb; 128(4):678-690. PubMed ID: 36476658
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5. p53 as a unique target of action of cisplatin in acute leukaemia cells.
Kumar S; Tchounwou PB
J Cell Mol Med; 2022 Sep; 26(17):4727-4739. PubMed ID: 35946055
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6. Enhancement of mdm2 inhibitory effects through blocking nuclear export mechanisms in ovarian cancer cells.
Alzahrani A; Natarajan U; Rathinavelu A
Cancer Genet; 2022 Aug; 266-267():57-68. PubMed ID: 35785714
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7. Larotrectinib in a Patient With Advanced Pleomorphic Liposarcoma of the Uterus.
Valenciaga A; Iwenofu OH; Tinoco G
J Natl Compr Canc Netw; 2021 Jul; 19(7):775-779. PubMed ID: 34340207
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8. Anti-cancer Tumor Cell Necrosis of Epithelial ovarian cancer Cell Lines Depends on High Expression of HDM-2 Protein in Their Membranes.
Thadi A; Gleeson EM; Khalili M; Shaikh MF; Goldstein E; Morano WF; Daniels LM; Grandhi N; Glatthorn H; Richard SD; Campbell PM; Sarafraz-Yazdi E; Pincus MR; Bowne WB
Ann Clin Lab Sci; 2020 Sep; 50(5):611-624. PubMed ID: 33067207
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9. Combination of metformin and RG7388 enhances inhibition of growth and induction of apoptosis of ovarian cancer cells through the PI3K/AKT/mTOR pathway.
Cui Y; Zhou J; Rong F
Biochem Biophys Res Commun; 2020 Dec; 533(4):665-671. PubMed ID: 33051060
[TBL] [Abstract] [Full Text] [Related]
10. Standardized Saponin Extract from Baiye No.1 Tea (
Tu Y; Chen L; Ren N; Li B; Wu Y; Rankin GO; Rojanasakul Y; Wang Y; Chen YC
Molecules; 2020 Jul; 25(15):. PubMed ID: 32752095
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11. Effect of murine double-minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys.
Kawata Y; Nagasaka K; Oda K; Makii C; Takeuchi M; Oki S; Honjo H; Kojima M; Miyagawa Y; Taguchi A; Tanikawa M; Sone K; Hiraike H; Matsumoto Y; Wada-Hiraike O; Ayabe T; Osuga Y; Fujii T
Cancer Sci; 2020 Oct; 111(10):3824-3834. PubMed ID: 32713096
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12. Apoptosis-related gene expression can predict the response of ovarian cancer cell lines to treatment with recombinant human TRAIL alone or combined with cisplatin.
Braga LDC; Gonçales NG; Furtado RS; Andrade WP; Silva LM; Silva Filho ALD
Clinics (Sao Paulo); 2020; 75():e1492. PubMed ID: 32187278
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13. Genomic and Molecular Abnormalities in Gynecologic Clear Cell Carcinoma.
Marks EI; Brown VS; Dizon DS
Am J Clin Oncol; 2020 Feb; 43(2):139-145. PubMed ID: 31764020
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14. Fn14 overcomes cisplatin resistance of high-grade serous ovarian cancer by promoting mdm2-mediated p53-R248Q ubiquitination and degradation.
Wu AY; Gu LY; Cang W; Cheng MX; Wang WJ; Di W; Huang L; Qiu LH
J Exp Clin Cancer Res; 2019 Apr; 38(1):176. PubMed ID: 31023317
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15. Overexpression of CCDC69 activates p14
Cui L; Zhou F; Chen C; Wang CC
J Ovarian Res; 2019 Jan; 12(1):4. PubMed ID: 30651135
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16. Proteomic investigating the cooperative lethal effect of EGFR and mdm2 inhibitors on ovarian carcinoma.
Chang SJ; Liao EC; Yeo HY; Kuo WH; Chen HY; Tsai YT; Wei YS; Chen YJ; Wang YS; Li JM; Shih CC; Chan CH; Lai ZY; Chou HC; Chuang YJ; Chan HL
Arch Biochem Biophys; 2018 Jun; 647():10-32. PubMed ID: 29655550
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17. The expression of TP53 pathway-related proteins in ovarian carcinoma transplanted subcutaneously in nude mice.
Zhang SR; Li DB; Xue JW
Eur Rev Med Pharmacol Sci; 2018 Mar; 22(5):1258-1264. PubMed ID: 29565482
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18. Analysis of defective protein ubiquitylation associated to adriamycin resistant cells.
Lang V; Aillet F; Xolalpa W; Serna S; Ceccato L; Lopez-Reyes RG; Lopez-Mato MP; Januchowski R; Reichardt NC; Rodriguez MS
Cell Cycle; 2017; 16(24):2337-2344. PubMed ID: 29099265
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19. mdm2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells.
Chen Y; Wang DD; Wu YP; Su D; Zhou TY; Gai RH; Fu YY; Zheng L; He QJ; Zhu H; Yang B
Br J Cancer; 2017 Oct; 117(8):1192-1201. PubMed ID: 28817834
[TBL] [Abstract] [Full Text] [Related]
20. Synergy between Paclitaxel and Anti-cancer Peptide PNC-27 in the treatment of ovarian cancer.
Alagkiozidis I; Gorelick C; Shah T; Chen YA; Gupta V; Stefanov D; Amarnani A; Lee YC; Abulafia O; Sarafraz-Yazdi E; Michl J
Ann Clin Lab Sci; 2017 May; 47(3):271-281. PubMed ID: 28667027
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