BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2 AND Treatment
53 results:

  • 1. Synergistic suppression of ovarian cancer by combining nrf2 and GPX4 inhibitors: in vitro and in vivo evidence.
    Li N; Jiang X; Zhang Q; Huang Y; Wei J; Zhang H; Luo H
    J Ovarian Res; 2024 Feb; 17(1):49. PubMed ID: 38396022
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. β-Sitosterol targets ASS1 for nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
    Wang H; Liu J; Zhang Z; Peng J; Wang Z; Yang L; Wang X; Hu S; Hong L
    Free Radic Biol Med; 2024 Mar; 214():137-157. PubMed ID: 38364944
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
    Bildik G; Gray JP; Mao W; Yang H; Ozyurt R; Orellana VR; De Wever O; Carey MS; Bast RC; Lu Z
    Autophagy; 2024 Mar; 20(3):675-691. PubMed ID: 38169324
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Interplay of oxidative stress, cellular communication and signaling pathways in cancer.
    Iqbal MJ; Kabeer A; Abbas Z; Siddiqui HA; Calina D; Sharifi-Rad J; Cho WC
    Cell Commun Signal; 2024 Jan; 22(1):7. PubMed ID: 38167159
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. FGF2 Rescued Cisplatin-Injured Granulosa Cells through the nrf2-Autophagy Pathway.
    Wang L; Cheng F; Pan R; Cui Z; She J; Zhang Y; Yang X
    Int J Mol Sci; 2023 Sep; 24(18):. PubMed ID: 37762517
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Potentiation of Cisplatin Cytotoxicity in Resistant ovarian cancer SKOV3/Cisplatin Cells by Quercetin Pre-treatment.
    Hasan AA; Kalinina E; Nuzhina J; Volodina Y; Shtil A; Tatarskiy V
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446140
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. A biscarbene gold(I)-NHC-complex overcomes cisplatin-resistance in A2780 and W1 ovarian cancer cells highlighting pERK as regulator of apoptosis.
    König P; Zhulenko R; Suparman E; Hoffmeister H; Bückreiß N; Ott I; Bendas G
    Cancer Chemother Pharmacol; 2023 Jul; 92(1):57-69. PubMed ID: 37272932
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
    Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
    Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the nrf2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
    Ma B; Zhong Y; Chen R; Zhan X; Huang G; Xiong Y; Tan B
    Biochem Biophys Res Commun; 2023 Jul; 665():178-186. PubMed ID: 37163938
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Apatinib combined with olaparib induces ferroptosis via a p53-dependent manner in ovarian cancer.
    Yue W; Yupeng G; Jun C; Kui J
    J Cancer Res Clin Oncol; 2023 Sep; 149(11):8681-8689. PubMed ID: 37120435
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. nrf2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.
    Anandhan A; Dodson M; Shakya A; Chen J; Liu P; Wei Y; Tan H; Wang Q; Jiang Z; Yang K; Garcia JG; Chambers SK; Chapman E; Ooi A; Yang-Hartwich Y; Stockwell BR; Zhang DD
    Sci Adv; 2023 Feb; 9(5):eade9585. PubMed ID: 36724221
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma.
    Raninga PV; He Y; Datta KK; Lu X; Maheshwari UR; Venkat P; Mayoh C; Gowda H; Kalimutho M; Hooper JD; Khanna KK
    Mol Ther; 2023 Mar; 31(3):729-743. PubMed ID: 36560881
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Fertility-Sparing Approach in Patients with Endometrioid Endometrial cancer Grade 2 Stage IA (FIGO): A Qualitative Systematic Review.
    Giampaolino P; Cafasso V; Boccia D; Ascione M; Mercorio A; Viciglione F; Palumbo M; Serafino P; Buonfantino C; De Angelis MC; Verrazzo P; Grasso G; Gullo G; Bifulco G; Della Corte L
    Biomed Res Int; 2022; 2022():4070368. PubMed ID: 36203482
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Inhibition of the PIN1-nrf2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells.
    Zhang Z; Hu Q; Ye S; Xiang L
    Acta Biochim Biophys Sin (Shanghai); 2022 Aug; 54(9):1325-1335. PubMed ID: 35983979
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP
    Chaiswing L; Yarana C; St Clair W; Tovmasyan A; Batinic-Haberle I; Spasojevic I; St Clair D
    Oxid Med Cell Longev; 2022; 2022():9664636. PubMed ID: 35898616
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. WASH regulates the oxidative stress nrf2/ARE pathway to inhibit proliferation and promote apoptosis of HeLa cells under the action of Jolkinolide B.
    Hong Y; Liu J; Kong W; Li H; Cui Y; Liu Y; Deng Z; Ma D; Zhang K; Li J; Li M
    PeerJ; 2022; 10():e13499. PubMed ID: 35855902
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Combination effect of poly (ADP-ribose) polymerase inhibitor and DNA demethylating agents for treatment of epithelial ovarian cancer.
    Shim JI; Ryu JY; Jeong SY; Cho YJ; Choi JJ; Hwang JR; Choi JY; Sa JK; Lee JW
    Gynecol Oncol; 2022 May; 165(2):270-280. PubMed ID: 35305818
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. AKR1C1/2 inhibition by MPA sensitizes platinum resistant ovarian cancer towards carboplatin.
    Badmann S; Mayr D; Schmoeckel E; Hester A; Buschmann C; Beyer S; Kolben T; Kraus F; Chelariu-Raicu A; Burges A; Mahner S; Jeschke U; Trillsch F; Czogalla B
    Sci Rep; 2022 Feb; 12(1):1862. PubMed ID: 35115586
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Enhanced Accumulation of Cisplatin in ovarian cancer Cells from Combination with Wedelolactone and Resulting Inhibition of Multiple Epigenetic Drivers.
    Sarwar S; Alamro AA; Alghamdi AA; Naeem K; Ullah S; Arif M; Yu JQ; Huq F
    Drug Des Devel Ther; 2021; 15():2211-2227. PubMed ID: 34079223
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the nrf2 pathway.
    Zhao F; Hong X; Li D; Wei Z; Ci X; Zhang S
    Med Oncol; 2021 Apr; 38(5):54. PubMed ID: 33811596
    [TBL] [Abstract] [Full Text] [Related]  


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