Terms: = Ovarian cancer AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C
36 results:
1. Epacadostat stabilizes the apo-form of IDO1 and signals a pro-tumorigenic pathway in human ovarian cancer cells.
Rossini S; Ambrosino S; Volpi C; Belladonna ML; Pallotta MT; Panfili E; Suvieri C; Macchiarulo A; Mondanelli G; Orabona C
Front Immunol; 2024; 15():1346686. PubMed ID: 38333210
[TBL] [Abstract] [Full Text] [Related]
2. shp2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy.
Drilon A; Sharma MR; Johnson ML; Yap TA; Gadgeel S; Nepert D; Feng G; Reddy MB; Harney AS; Elsayed M; Cook AW; Wong CE; Hinklin RJ; Jiang Y; Brown EN; Neitzel NA; Laird ER; Wu WI; Singh A; Wei P; Ching KA; Gaudino JJ; Lee PA; Hartley DP; Rothenberg SM
Cancer Discov; 2023 Aug; 13(8):1789-1801. PubMed ID: 37269335
[TBL] [Abstract] [Full Text] [Related]
3. Disruption of ovarian cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase.
Lazo JS; Isbell KN; Vasa SA; Llaneza DC; Rastelli EJ; Wipf P; Sharlow ER
J Pharmacol Exp Ther; 2023 Mar; 384(3):429-438. PubMed ID: 36627205
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4. Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma.
Murumägi A; Ungureanu D; Khan S; Arjama M; Välimäki K; Ianevski A; Ianevski P; Bergström R; Dini A; Kanerva A; Koivisto-Korander R; Tapper J; Lassus H; Loukovaara M; Mägi A; Hirasawa A; Aoki D; Pietiäinen V; Pellinen T; Bützow R; Aittokallio T; Kallioniemi O
Br J Cancer; 2023 Feb; 128(4):678-690. PubMed ID: 36476658
[TBL] [Abstract] [Full Text] [Related]
5. Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN; Zhao XJ; Wang Z; Luo MS; Shi SN; Yan DM; Li HY; Liu JH; Yang Y; Tan JH; Zhang ZY; Chen RQ; Lai HL; Huang XY; Zhou JF; Ma D; Fang Y; Gao QL
Signal Transduct Target Ther; 2022 Sep; 7(1):317. PubMed ID: 36097006
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6. shp2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple cancer Models.
Fedele C; Ran H; Diskin B; Wei W; Jen J; Geer MJ; Araki K; Ozerdem U; Simeone DM; Miller G; Neel BG; Tang KH
Cancer Discov; 2018 Oct; 8(10):1237-1249. PubMed ID: 30045908
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7. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and shp2 inhibition.
Wong GS; Zhou J; Liu JB; Wu Z; Xu X; Li T; Xu D; Schumacher SE; Puschhof J; McFarland J; Zou C; Dulak A; Henderson L; Xu P; O'Day E; Rendak R; Liao WL; Cecchi F; Hembrough T; Schwartz S; Szeto C; Rustgi AK; Wong KK; Diehl JA; Jensen K; Graziano F; Ruzzo A; Fereshetian S; Mertins P; Carr SA; Beroukhim R; Nakamura K; Oki E; Watanabe M; Baba H; Imamura Y; Catenacci D; Bass AJ
Nat Med; 2018 Jul; 24(7):968-977. PubMed ID: 29808010
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8. EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ ovarian cancer Cells.
Bai S; Ingram P; Chen YC; Deng N; Pearson A; Niknafs YS; O'Hayer P; Wang Y; Zhang ZY; Boscolo E; Bischoff J; Yoon E; Buckanovich RJ
Cancer Res; 2016 Nov; 76(21):6396-6409. PubMed ID: 27803106
[TBL] [Abstract] [Full Text] [Related]
9. HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer.
Fan G; Zhang S; Gao Y; Greer PA; Tonks NK
Genes Dev; 2016 Jul; 30(13):1542-57. PubMed ID: 27401557
[TBL] [Abstract] [Full Text] [Related]
10. PD-1 Blunts the Function of ovarian Tumor-Infiltrating Dendritic Cells by Inactivating NF-κB.
Karyampudi L; Lamichhane P; Krempski J; Kalli KR; Behrens MD; Vargas DM; Hartmann LC; Janco JM; Dong H; Hedin KE; Dietz AB; Goode EL; Knutson KL
Cancer Res; 2016 Jan; 76(2):239-50. PubMed ID: 26567141
[TBL] [Abstract] [Full Text] [Related]
11. Functional characterization of epithelial ovarian cancer histotypes by drug target based protein signaling activation mapping: implications for personalized cancer therapy.
Sereni MI; Baldelli E; Gambara G; Deng J; Zanotti L; Bandiera E; Bignotti E; Ragnoli M; Tognon G; Ravaggi A; Meani F; Memo M; Angioli R; Liotta LA; Pecorelli SL; Petricoin E; Pierobon M
Proteomics; 2015 Jan; 15(2-3):365-73. PubMed ID: 25311472
[TBL] [Abstract] [Full Text] [Related]
12. GAB2--a scaffolding protein in cancer.
Adams SJ; Aydin IT; Celebi JT
Mol Cancer Res; 2012 Oct; 10(10):1265-70. PubMed ID: 22871571
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13. Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells.
Wang Y; Sheng Q; Spillman MA; Behbakht K; Gu H
Oncogene; 2012 May; 31(20):2512-20. PubMed ID: 21996746
[TBL] [Abstract] [Full Text] [Related]
14. Proteasome particle-rich structures are widely present in human epithelial neoplasms: correlative light, confocal and electron microscopy study.
Necchi V; Sommi P; Vanoli A; Manca R; Ricci V; Solcia E
PLoS One; 2011; 6(6):e21317. PubMed ID: 21695063
[TBL] [Abstract] [Full Text] [Related]
15. Germline mutation in BRAF codon 600 is compatible with human development: de novo p.V600G mutation identified in a patient with cfc syndrome.
Champion KJ; Bunag C; Estep AL; Jones JR; Bolt CH; Rogers RC; Rauen KA; Everman DB
Clin Genet; 2011 May; 79(5):468-74. PubMed ID: 20735442
[TBL] [Abstract] [Full Text] [Related]
16. Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells.
Saydmohammed M; Joseph D; Syed V
J Cell Biochem; 2010 May; 110(2):447-56. PubMed ID: 20235152
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17. Stimulation of human T cells by an influenza A vector expressing a CTL epitope from the HER-2/neu protooncogene results in higher numbers of antigen-specific TCRhi cells than stimulation with peptide. Divergent roles of IL-2 and IL-15.
Efferson CL; Kawano K; Tsuda N; Palese P; García-Sastre A; Ioannides CG
Anticancer Res; 2005; 25(2A):715-24. PubMed ID: 15868901
[TBL] [Abstract] [Full Text] [Related]
18. Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene.
Efferson CL; Schickli J; Ko BK; Kawano K; Mouzi S; Palese P; García-Sastre A; Ioannides CG
J Virol; 2003 Jul; 77(13):7411-24. PubMed ID: 12805440
[TBL] [Abstract] [Full Text] [Related]
19. Cripto: a tumor growth factor and more.
Adamson ED; Minchiotti G; Salomon DS
J Cell Physiol; 2002 Mar; 190(3):267-78. PubMed ID: 11857442
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20. Transient detection of beta-galactosidase activity in hematopoietic cells, following reinjection of retrovirally marked autologous blood progenitors in patients with breast or ovarian cancer receiving high-dose chemotherapy.
Bagnis C; Chabannon C; Gravis G; Imbert AM; Maroc C; Bardin F; Ladaique P; Viret F; Genre D; Faucher C; Stoppa AM; Vey N; Blaise D; Maraninchi D; Viens P; Mannoni P
Exp Hematol; 2002 Feb; 30(2):108-15. PubMed ID: 11823045
[TBL] [Abstract] [Full Text] [Related]
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