BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND TSC1, KIAA0243, 7248, ENSG00000165699, TSC, MGC86987, LAM, hamartin
40 results:

  • 1. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
    Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
    Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Translation of the efficacy of antibody-drug conjugates from preclinical to clinical using a semimechanistic PK/PD model: A case study with RC88.
    Li Q; Wang L; Zhang J; Zhao G; Liu Z; Ma X; Jiang J
    Clin Transl Sci; 2023 Jul; 16(7):1232-1242. PubMed ID: 37259689
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Synthesis and Antiproliferative Activity of Steroidal Diaryl Ethers.
    Kovács É; Ali H; Minorics R; Traj P; Resch V; Paragi G; Bruszel B; Zupkó I; Mernyák E
    Molecules; 2023 Jan; 28(3):. PubMed ID: 36770863
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Anti-Proliferative Acyl Phenols and Arylnonanoids from the Fruit Rind of Myristica malabarica lam.
    Bauri AK; Du Y; Brodie PJ; Foro S; Kingston DGI
    Chem Biodivers; 2022 Dec; 19(12):e202200343. PubMed ID: 36263966
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. TP53 variant allele frequency correlates with the chemotherapy response score in ovarian/fallopian tube/peritoneal high-grade serous carcinoma.
    Lawson BC; Yang RK; Euscher ED; Ramalingam P; Malpica A
    Hum Pathol; 2021 Sep; 115():76-83. PubMed ID: 34153306
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Role of tsc1 in physiology and diseases.
    Mallela K; Kumar A
    Mol Cell Biochem; 2021 Jun; 476(6):2269-2282. PubMed ID: 33575875
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Time Trends in Receipt of Germline Genetic Testing and Results for Women Diagnosed With Breast cancer or ovarian cancer, 2012-2019.
    Kurian AW; Ward KC; Abrahamse P; Bondarenko I; Hamilton AS; Deapen D; Morrow M; Berek JS; Hofer TP; Katz SJ
    J Clin Oncol; 2021 May; 39(15):1631-1640. PubMed ID: 33560870
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Neuroendocrine Neoplasms Associated with Germline Pathogenic Variants in the Homologous Recombination Pathway.
    Szybowska M; Mete O; Weber E; Silver J; Kim RH
    Endocr Pathol; 2019 Sep; 30(3):237-245. PubMed ID: 30772928
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Clinicopathological analysis of clinically occult extrapulmonary lymphangioleiomyomatosis in intra-pelvic and para-aortic lymph nodes associated with pelvic malignant tumors: A study of nine patients.
    Uehara K; Kawakami F; Hirose T; Morita H; Kudo E; Yasuda M; Märkl B; Zen Y; Itoh T; Imai Y
    Pathol Int; 2019 Jan; 69(1):29-36. PubMed ID: 30688413
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for cancer and Neurological Disorders.
    Rageot D; Bohnacker T; Melone A; Langlois JB; Borsari C; Hillmann P; Sele AM; Beaufils F; Zvelebil M; Hebeisen P; Löscher W; Burke J; Fabbro D; Wymann MP
    J Med Chem; 2018 Nov; 61(22):10084-10105. PubMed ID: 30359003
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Screening organometallic thiophene containing thiosemicarbazone ruthenium (II/III) complexes as potential anti-tumour agents.
    Tavsan Z; Yaman PK; Subasi E; Kayali HA
    J Biol Inorg Chem; 2018 May; 23(3):425-435. PubMed ID: 29569084
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Genomic landscape of ovarian clear cell carcinoma via whole exome sequencing.
    Kim SI; Lee JW; Lee M; Kim HS; Chung HH; Kim JW; Park NH; Song YS; Seo JS
    Gynecol Oncol; 2018 Feb; 148(2):375-382. PubMed ID: 29233531
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. miR-130a upregulates mTOR pathway by targeting tsc1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma.
    Wang Y; Zhang X; Tang W; Lin Z; Xu L; Dong R; Li Y; Li J; Zhang Z; Li X; Zhao L; Wei JJ; Shao C; Kong B; Liu Z
    Cell Death Differ; 2017 Dec; 24(12):2089-2100. PubMed ID: 28800130
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. CA-125 in Disease Progression and Treatment of Lymphangioleiomyomatosis.
    Glasgow CG; Pacheco-Rodriguez G; Steagall WK; Haughey ME; Julien-Williams PA; Stylianou MP; Gochuico BR; Moss J
    Chest; 2018 Feb; 153(2):339-348. PubMed ID: 28576630
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Sweet Potato Peels and cancer Prevention.
    Oluyori AP; Shaw AK; Olatunji GA; Rastogi P; Meena S; Datta D; Arora A; Reddy S; Puli S
    Nutr Cancer; 2016; 68(8):1330-1337. PubMed ID: 27673552
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Technetium Tc 99m sulfur colloid phenotypic probe for the pharmacokinetics and pharmacodynamics of PEGylated liposomal doxorubicin in women with ovarian cancer.
    Giovinazzo H; Kumar P; Sheikh A; Brooks KM; Ivanovic M; Walsh M; Caron WP; Kowalsky RJ; Song G; Whitlow A; Clarke-Pearson DL; Brewster WR; Van Le L; Zamboni BA; Bae-Jump V; Gehrig PA; Zamboni WC
    Cancer Chemother Pharmacol; 2016 Mar; 77(3):565-73. PubMed ID: 26822231
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. MARCKSL1 exhibits anti-angiogenic effects through suppression of VEGFR-2-dependent Akt/PDK-1/mTOR phosphorylation.
    Kim BR; Lee SH; Park MS; Seo SH; Park YM; Kwon YJ; Rho SB
    Oncol Rep; 2016 Feb; 35(2):1041-8. PubMed ID: 26555156
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Malignant presentation of uterine lymphangioleiomyomatosis.
    Szpurek D; Szubert S; Zielinski P; Frankowski A; Sajdak S; Moszynski R
    Taiwan J Obstet Gynecol; 2015 Oct; 54(5):603-7. PubMed ID: 26522119
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Death-associated protein kinase 1 promotes growth of p53-mutant cancers.
    Zhao J; Zhao D; Poage GM; Mazumdar A; Zhang Y; Hill JL; Hartman ZC; Savage MI; Mills GB; Brown PH
    J Clin Invest; 2015 Jul; 125(7):2707-20. PubMed ID: 26075823
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Incidental Pelvic and Para-aortic Lymph Node Lymphangioleiomyomatosis Detected During Surgical Staging of Pelvic cancer in Women Without Symptomatic Pulmonary Lymphangioleiomyomatosis or Tuberous Sclerosis Complex.
    Rabban JT; Firetag B; Sangoi AR; Post MD; Zaloudek CJ
    Am J Surg Pathol; 2015 Aug; 39(8):1015-25. PubMed ID: 25786086
    [TBL] [Abstract] [Full Text] [Related]  


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