BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND BRD4, O60885, 23476, ENSG00000141867, HUNKI, CAP, MCAP AND Treatment
80 results:

  • 1. Inhibition of Bromodomain Proteins Enhances Oncolytic HAdVC5 Replication and Efficacy in pancreatic Ductal Adenocarcinoma (PDAC) Models.
    Miao T; Symonds A; Hickman OJ; Wu D; Wang P; Lemoine N; Wang Y; Linardopoulos S; Halldén G
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38279262
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Radiosensitizing Favors Response to Peptide Receptor Radionuclide Therapy in Patients With Highly Proliferative Neuroendocrine Malignancies: Preliminary Evidence From a Clinical Pilot Study.
    Trautwein NF; Hinterleitner C; Kiefer LS; Singer S; Mattern S; Schwenck J; Reischl G; Sipos B; Lauer UM; Dittmann H; Zender L; la Fougère C; Hinterleitner M
    Clin Nucl Med; 2024 Mar; 49(3):207-214. PubMed ID: 38271237
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The Usefulness of Elastin Staining to Detect Vascular Invasion in cancer.
    Gonzalez J; Bahmad HF; Ocejo S; Abreu A; Popp M; Gogola S; Fernandez V; Recine M; Poppiti R
    Int J Mol Sci; 2023 Oct; 24(20):. PubMed ID: 37894944
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Targeted delivery of PROTAC-based prodrug activated by bond-cleavage bioorthogonal chemistry for microneedle-assisted cancer therapy.
    Huang J; Yao Z; Li B; Ping Y
    J Control Release; 2023 Sep; 361():270-279. PubMed ID: 37541594
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. First-in-human Study of AZD5153, A Small-molecule Inhibitor of Bromodomain Protein 4, in Patients with Relapsed/Refractory Malignant Solid Tumors and Lymphoma.
    Hamilton EP; Wang JS; Oza AM; Patel MR; Ulahannan SV; Bauer T; Karlix JL; Zeron-Medina J; Fabbri G; Marco-Casanova P; Moorthy G; Hattersley MM; Littlewood GM; Mitchell P; Saeh J; Pouliot GP; Moore KN
    Mol Cancer Ther; 2023 Oct; 22(10):1154-1165. PubMed ID: 37486983
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Arterial events in cancer patients treated with apixaban for venous thrombosis.
    Larsen TL; Svalastoga M; Brekke J; Enden T; Frøen H; Garresori H; Jacobsen EM; Paulsen PQ; Porojnicu AC; Ree AH; Torfoss D; Velle EO; Wik HS; Ghanima W; Sandset PM; Dahm AEA
    Thromb Res; 2023 Aug; 228():128-133. PubMed ID: 37327527
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Acid sphingomyelinase expression is associated with survival in resectable pancreatic ductal adenocarcinoma.
    Wilson GC; Patel SH; Wang J; Xu K; Turner KM; Becker KA; Carpinteiro A; Szabo I; Ahmad SA; Gulbins E
    J Mol Med (Berl); 2023 Jul; 101(7):891-903. PubMed ID: 37246980
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Pathologic Tumor Regression is Associated With Improved Survival in pancreatic cancer.
    Nicolais LM; Caron M; Verdini N; Fitzgerald TL
    Am Surg; 2023 Sep; 89(9):3778-3783. PubMed ID: 37227766
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Prognostic value of major pathological response following neoadjuvant therapy for non resectable pancreatic ductal adenocarcinoma.
    Bao QR; Frigerio I; Tripepi M; Marletta S; Martignoni G; Giardino A; Regi P; Scopelliti F; Allegrini V; Girelli R; Pucciarelli S; Spolverato G; Butturini G
    Pancreatology; 2023 Apr; 23(3):266-274. PubMed ID: 36841686
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Design, Synthesis, and Biological Evaluation of a Potent Dual EZH2-brd4 Inhibitor for the treatment of Some Solid Tumors.
    Huang N; Liao P; Zuo Y; Zhang L; Jiang R
    J Med Chem; 2023 Feb; 66(4):2646-2662. PubMed ID: 36774555
    [TBL] [Abstract] [Full Text] [Related]  

  • 11.
    Darabi S; Braxton DR; Xiu J; Carneiro BA; Swensen J; Antonarakis ES; Liu SV; McKay RR; Spetzler D; El-Deiry WS; Demeure MJ
    Medicina (Kaunas); 2022 Dec; 58(12):. PubMed ID: 36557020
    [No Abstract]    [Full Text] [Related]  

  • 12. Histopathological tumour response scoring in resected pancreatic cancer following neoadjuvant therapy: international interobserver study (ISGPP-1).
    Janssen BV; van Roessel S; van Dieren S; de Boer O; Adsay V; Basturk O; Brosens L; Campbell F; Chatterjee D; Chou A; Doglioni C; Esposito I; Feakins R; Fuchs TL; Fukushima N; Gill AJ; Hong SM; Hruban RH; Kaplan J; Krasinkas A; Luchini C; Shi C; Singhi A; Thompson E; Velthuysen MF; Besselink MG; Verheij J; Wang H; Verbeke C; Fariña A;
    Br J Surg; 2022 Dec; 110(1):67-75. PubMed ID: 36331867
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Critical issues in pathologic evaluation of pancreatic ductal adenocarcinoma resected after neoadjuvant treatment: a narrative review.
    Taherian M; Wang H
    Chin Clin Oncol; 2022 Jun; 11(3):21. PubMed ID: 35726190
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Design and Synthesis of Dual EZH2/brd4 Inhibitors to Target Solid Tumors.
    Guo Z; Sun Y; Liang L; Lu W; Luo B; Wu Z; Huo B; Hu Y; Huang P; Wu Q; Wen S
    J Med Chem; 2022 May; 65(9):6573-6592. PubMed ID: 35500243
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The optimal duration of capecitabine plus temozolomide in patients with well-differentiated pancreatic NETs with or without maintenance therapy.
    Gao H; Dong J; Zhang W; Xu H; Ye L; Li H; Wang W; Liu L; Yu X
    J Neuroendocrinol; 2022 Jun; 34(6):e13112. PubMed ID: 35380016
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Cold Atmospheric Plasma Does Not Affect Stellate Cells Phenotype in pancreatic cancer Tissue in Ovo.
    Privat-Maldonado A; Verloy R; Cardenas Delahoz E; Lin A; Vanlanduit S; Smits E; Bogaerts A
    Int J Mol Sci; 2022 Feb; 23(4):. PubMed ID: 35216069
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Design, synthesis and mechanism studies of novel dual PARP1/brd4 inhibitors against pancreatic cancer.
    Huang SH; Cao R; Lin QW; Wu SQ; Gao LL; Sun Q; Zhu QH; Zou Y; Xu YG; Wang SP
    Eur J Med Chem; 2022 Feb; 230():114116. PubMed ID: 35091172
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Chromatin Remodeling Induced by ARID1A Loss in Lung cancer Promotes Glycolysis and Confers JQ1 Vulnerability.
    Liu X; Li Z; Wang Z; Liu F; Zhang L; Ke J; Xu X; Zhang Y; Yuan Y; Wei T; Shan Q; Chen Y; Huang W; Gao J; Wu N; Chen F; Sun L; Qiu Z; Deng Y; Wang X
    Cancer Res; 2022 Mar; 82(5):791-804. PubMed ID: 34987057
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Discovery of Potent and Novel Dual PARP/brd4 Inhibitors for Efficient treatment of pancreatic cancer.
    Wang SP; Li Y; Huang SH; Wu SQ; Gao LL; Sun Q; Lin QW; Huang L; Meng LQ; Zou Y; Zhu QH; Xu YG
    J Med Chem; 2021 Dec; 64(23):17413-17435. PubMed ID: 34813314
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Bromodomain-containing protein 4 inhibitor JQ1 promotes melanoma cell apoptosis by regulating mitochondrial dynamics.
    Li L; Meng Y; Wu X; Li J; Sun Y
    Cancer Sci; 2021 Oct; 112(10):4013-4025. PubMed ID: 34252226
    [TBL] [Abstract] [Full Text] [Related]  


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