Terms: = Pancreatic cancer AND CDK4, PSK-J3, 1019, ENSG00000135446, MGC14458, CMM3, P11802
230 results:
1. cdk4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma.
Cheng K; Zhou Z; Chen Q; Chen Z; Cai Y; Cai H; Wu S; Gao P; Cai Y; Zhou J; Wang X; Wu Z; Peng B
Sci Rep; 2024 Apr; 14(1):8389. PubMed ID: 38600093
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2. PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation.
Palanivel C; Madduri LSV; Hein AL; Jenkins CB; Graff BT; Camero AL; Zhou S; Enke CA; Ouellette MM; Yan Y
Aging (Albany NY); 2024 Mar; 16(5):4116-4137. PubMed ID: 38441530
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3. ER-positive and BRCA2-mutated breast cancer: a literature review.
Li PC; Zhu YF; Cao WM; Li B
Eur J Med Res; 2024 Jan; 29(1):30. PubMed ID: 38184581
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4. SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma.
Man KF; Zhou L; Yu H; Lam KH; Cheng W; Yu J; Lee TK; Yun JP; Guan XY; Liu M; Ma S
Nat Commun; 2023 Nov; 14(1):7863. PubMed ID: 38030644
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5. Characterization of Potential Melanoma Predisposition Genes in High-Risk Brazilian Patients.
Soares de Sá BC; Moredo LF; Torrezan GT; Fidalgo F; de Araújo ÉSS; Formiga MN; Duprat JP; Carraro DM
Int J Mol Sci; 2023 Oct; 24(21):. PubMed ID: 37958811
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6. Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer.
Kang HW; Kim JH; Lee DE; Lee YS; Kim MJ; Kim HS; Fang S; Lee BE; Lee KJ; Yoo J; Kim HJ; Park JS
Cancer Biol Ther; 2023 Dec; 24(1):2272334. PubMed ID: 37917550
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7. The SGK3-Catalase antioxidant signaling axis drives cervical cancer growth and therapy resistance.
Wang M; Liu J; Liao X; Yi Y; Xue Y; Yang L; Cheng H; Liu P
Redox Biol; 2023 Nov; 67():102931. PubMed ID: 37866161
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8. A real-world analysis of trametinib in combination with hydroxychloroquine or cdk4/6 inhibitor as third- or later-line therapy in metastatic pancreatic adenocarcinoma.
Tang H; Ge Y; You T; Li X; Wang Y; Cheng Y; Bai C
BMC Cancer; 2023 Oct; 23(1):958. PubMed ID: 37817078
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9. Targeted inhibition of mTOR by BML-275 induces mitochondrial-mediated apoptosis and autophagy in prostate cancer.
Li W; Li D; Ma Q; Chen Y; Hu Z; Bai Y; Xie L
Eur J Pharmacol; 2023 Oct; 957():176035. PubMed ID: 37657741
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10. High- and intermediate-risk susceptibility variants in melanoma families from the Mediterranean area: A multicentre cohort from the MelaNostrum Consortium.
Pellegrini C; Cardelli L; Ghiorzo P; Pastorino L; Potrony M; García-Casado Z; Elefanti L; Stefanaki I; Mastrangelo M; Necozione S; Aguilera P; Rodríguez-Hernández A; Di Nardo L; Rocco T; Del Regno L; Badenas C; Carrera C; Malvehy J; Requena C; Bañuls J; Stratigos AJ; Peris K; Menin C; Calista D; Nagore E; Puig S; Landi MT; Fargnoli MC
J Eur Acad Dermatol Venereol; 2023 Dec; 37(12):2498-2508. PubMed ID: 37611275
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11. E3 ligase MG53 suppresses tumor growth by degrading cyclin D1.
Fang M; Wu HK; Pei Y; Zhang Y; Gao X; He Y; Chen G; Lv F; Jiang P; Li Y; Li W; Jiang P; Wang L; Ji J; Hu X; Xiao RP
Signal Transduct Target Ther; 2023 Jul; 8(1):263. PubMed ID: 37414783
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12. CDKN2A/cdk4 status in Brazilian patients meeting clinical criteria for hereditary melanoma: a cross-sectional descriptive trial.
Arnaut JRMB; Guimarães IDS; Dos Santos ACE; Rodrigues EM; Machado JRDS; de Melo AC
Int J Dermatol; 2023 Aug; 62(8):1060-1066. PubMed ID: 37322831
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13. Molecular and Functional Heterogeneity of Primary pancreatic Neuroendocrine Tumors and Metastases.
Guo Y; Tian C; Cheng Z; Chen R; Li Y; Su F; Shi Y; Tan H
Neuroendocrinology; 2023; 113(9):943-956. PubMed ID: 37232011
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14. Clonal evolution during metastatic spread in high-risk neuroblastoma.
Gundem G; Levine MF; Roberts SS; Cheung IY; Medina-Martínez JS; Feng Y; Arango-Ossa JE; Chadoutaud L; Rita M; Asimomitis G; Zhou J; You D; Bouvier N; Spitzer B; Solit DB; Dela Cruz F; LaQuaglia MP; Kushner BH; Modak S; Shukla N; Iacobuzio-Donahue CA; Kung AL; Cheung NV; Papaemmanuil E
Nat Genet; 2023 Jun; 55(6):1022-1033. PubMed ID: 37169874
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15. Inhibiting cdk4/6 in pancreatic ductal adenocarcinoma via microRNA-21.
Mortoglou M; Miralles F; Mould RR; Sengupta D; Uysal-Onganer P
Eur J Cell Biol; 2023 Jun; 102(2):151318. PubMed ID: 37105116
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16. A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas.
Hidalgo M; Garcia-Carbonero R; Lim KH; Messersmith WA; Garrido-Laguna I; Borazanci E; Lowy AM; Medina Rodriguez L; Laheru D; Salvador-Barbero B; Malumbres M; Shields DJ; Grossman JE; Huang X; Tammaro M; Martini JF; Yu Y; Kern K; Macarulla T
Cancer Res Commun; 2022 Nov; 2(11):1326-1333. PubMed ID: 36970055
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17. First diagnosed invasive lobular carcinoma of the breast combined with gastric metastasis and bone metastasis: a case report and review of the literature.
Sun L; Liu J; Guo M; Xu J; Wang D
BMC Womens Health; 2023 Mar; 23(1):133. PubMed ID: 36966290
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18. MYC-mediated resistance to trametinib and HCQ in PDAC is overcome by cdk4/6 and lysosomal inhibition.
Silvis MR; Silva D; Rohweder R; Schuman S; Gudipaty S; Truong A; Yap J; Affolter K; McMahon M; Kinsey C
J Exp Med; 2023 Mar; 220(3):. PubMed ID: 36719686
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19. Tumor-suppressive role of microfibrillar associated protein 4 and its clinical significance as prognostic factor and diagnostic biomarker in hepatocellular carcinoma.
Li J; Wang J; Liu Z; Guo H; Wei X; Wei Q; Zheng S; Xu X
J Cancer Res Ther; 2022 Dec; 18(7):1919-1925. PubMed ID: 36647950
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20. Combined inhibition of ACLY and cdk4/6 reduces cancer cell growth and invasion.
Velez BC; Petrella CP; DiSalvo KH; Cheng K; Kravtsov R; Krasniqi D; Krucher NA
Oncol Rep; 2023 Feb; 49(2):. PubMed ID: 36562384
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