BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND CDKN1B, CDKN4, 1027, ENSG00000111276, MEN4, P27KIP1, P46527, MEN1B, KIP1 AND Treatment
44 results:

  • 1. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
    Bildik G; Gray JP; Mao W; Yang H; Ozyurt R; Orellana VR; De Wever O; Carey MS; Bast RC; Lu Z
    Autophagy; 2024 Mar; 20(3):675-691. PubMed ID: 38169324
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Integrative Pan-cancer Genomic and Transcriptomic Analyses of Refractory Metastatic cancer.
    Pradat Y; Viot J; Yurchenko AA; Gunbin K; Cerbone L; Deloger M; Grisay G; Verlingue L; Scott V; Padioleau I; Panunzi L; Michiels S; Hollebecque A; Jules-Clément G; Mezquita L; Lainé A; Loriot Y; Besse B; Friboulet L; André F; Cournède PH; Gautheret D; Nikolaev SI
    Cancer Discov; 2023 May; 13(5):1116-1143. PubMed ID: 36862804
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. FOLFIRINOX or gemcitabine/nab-paclitaxel in advanced pancreatic adenocarcinoma: A novel validated prognostic score to facilitate treatment decision-making in real-world.
    Marschner N; Hegewisch-Becker S; Reiser M; von der Heyde E; Bertram M; Hollerbach SH; Kreher S; Wolf T; Binninger A; Chiabudini M; Kaiser-Osterhues A; Jänicke M;
    Int J Cancer; 2023 Feb; 152(3):458-469. PubMed ID: 36053905
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies.
    Ruggeri RM; Benevento E; De Cicco F; Fazzalari B; Guadagno E; Hasballa I; Tarsitano MG; Isidori AM; Colao A; Faggiano A;
    J Endocrinol Invest; 2023 Feb; 46(2):213-234. PubMed ID: 36038743
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Functional assessment of miR‑1291 in colon cancer cells.
    Wang J; Yokoyama Y; Hirose H; Shimomura Y; Bonkobara S; Itakura H; Kouda S; Morimoto Y; Minami K; Takahashi H; Shibata S; Kobayashi S; Uemura M; Tanaka S; Wu X; Tanaka S; Mori M; Yamamoto H
    Int J Oncol; 2022 Feb; 60(2):. PubMed ID: 34981812
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets.
    van Riet J; van de Werken HJG; Cuppen E; Eskens FALM; Tesselaar M; van Veenendaal LM; Klümpen HJ; Dercksen MW; Valk GD; Lolkema MP; Sleijfer S; Mostert B
    Nat Commun; 2021 Jul; 12(1):4612. PubMed ID: 34326338
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Pitavastatin and metformin synergistically activate apoptosis and autophagy in pancreatic cancer cells.
    Chen YH; Huang YC; Yang SF; Yen HH; Tsai HD; Hsieh MC; Hsiao YH
    Environ Toxicol; 2021 Aug; 36(8):1491-1503. PubMed ID: 33886150
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Clinical Application of Trans-Arterial Radioembolization in Hepatic Malignancies in Europe: First Results from the Prospective Multicentre Observational Study CIRSE Registry for SIR-Spheres Therapy (CIRT).
    Helmberger T; Golfieri R; Pech M; Pfammatter T; Arnold D; Cianni R; Maleux G; Munneke G; Pellerin O; Peynircioglu B; Sangro B; Schaefer N; de Jong N; Bilbao JI; ;
    Cardiovasc Intervent Radiol; 2021 Jan; 44(1):21-35. PubMed ID: 32959085
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Agonists of growth hormone-releasing hormone (GHRH) inhibit human experimental cancers in vivo by down-regulating receptors for GHRH.
    Schally AV; Wang H; He J; Cai R; Sha W; Popovics P; Perez R; Vidaurre I; Zhang X
    Proc Natl Acad Sci U S A; 2018 Nov; 115(47):12028-12033. PubMed ID: 30373845
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Tetrandrine inhibits deregulated cell cycle in pancreatic cancer cells: Differential regulation of p21
    Singh K; Dong Q; TimiriShanmugam PS; Koul S; Koul HK
    Cancer Lett; 2018 Jul; 425():164-173. PubMed ID: 29605511
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. pancreaticoduodenectomy is justified in a subset of elderly patients with pancreatic ductal adenocarcinoma: A population-based retrospective cohort study of 4,283 patients.
    Lu L; Zhang X; Tang G; Shang Y; Liu P; Wei Y; Gong P; Ma L
    Int J Surg; 2018 May; 53():262-268. PubMed ID: 29604352
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. [Multiple Endocrine Neoplasia I (Wermers Syndrome), Forms of Clinical Manifestation, 5 Case Studies].
    Drbalová K; Herdová K; Krejčí P; Nývltová M; Solař S; Vedralová L; Záruba P; Netuka D; Bavor P
    Vnitr Lek; 2016; 62(9 Suppl 3):140-149. PubMed ID: 27734708
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression.
    Li GQ; Guo WZ; Zhang Y; Seng JJ; Zhang HP; Ma XX; Zhang G; Li J; Yan B; Tang HW; Li SS; Wang LD; Zhang SJ
    Oncotarget; 2016 Jan; 7(3):2462-74. PubMed ID: 26575167
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway.
    Zhao Z; Li C; Xi H; Gao Y; Xu D
    Mol Med Rep; 2015 Oct; 12(4):5415-22. PubMed ID: 26166196
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F; Wang Q; Zhou ZW; Yu SN; Pan ST; He ZX; Zhang X; Wang D; Yang YX; Yang T; Sun T; Li M; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():537-60. PubMed ID: 25632222
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Pancreas-preserving duodenectomy is a safe alternative to high-risk pancreatoduodenectomy for premalignant duodenal lesions.
    Rangelova E; Blomberg J; Ansorge C; Lundell L; Segersvärd R; Del Chiaro M
    J Gastrointest Surg; 2015 Mar; 19(3):492-7. PubMed ID: 25564323
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Differences in respiratory-induced pancreatic tumor motion between 4D treatment planning CT and daily cone beam CT, measured using intratumoral fiducials.
    Lens E; van der Horst A; Kroon PS; van Hooft JE; Dávila Fajardo R; Fockens P; van Tienhoven G; Bel A
    Acta Oncol; 2014 Sep; 53(9):1257-64. PubMed ID: 24758251
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. MicroRNA-221 mediates the effects of PDGF-BB on migration, proliferation, and the epithelial-mesenchymal transition in pancreatic cancer cells.
    Su A; He S; Tian B; Hu W; Zhang Z
    PLoS One; 2013; 8(8):e71309. PubMed ID: 23967190
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer.
    Venkannagari S; Fiskus W; Peth K; Atadja P; Hidalgo M; Maitra A; Bhalla KN
    Oncotarget; 2012 Nov; 3(11):1416-27. PubMed ID: 23232026
    [TBL] [Abstract] [Full Text] [Related]  


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